tumor-bearing rats
Liver cytochrome P450-hydroxylation system of tumor-bearing rats under the influence of ω-3 polyunsaturated fatty acids and vitamin D(3)
... of tumor cells, reducing proliferation, metasta- sis formation and increasing the apoptotic death of transformed cells [18], it was advisable to test their separate and combined effects in the liver of ...
9
Free radical oxidation in liver mitochondria of tumor-bearing rats and its correction by essential lipophilic nutrients
... to rats with transplanted Guerin’s carcinoma was ...intensive tumor growth (14 days) the increase of superoxide radical generation and the content of primary (triene conjugates, tc), secondary (ketodienes ...
8
Changes in oxidative stress intensity in blood of tumor-bearing rats following different modes of administration of rhenium-platinum system
... in tumor growth inhibition: the adminis tration of liposomal forms or solution re- sulted in less tumor inhibition compared to adminis- tration of solid nanoparticles loaded with ...to ...
11
The concentration of ceruloplasmin in blood of tumor-bearing rats after administration of a dirhenium(III) compound and cisplatin
... with tumor-containing animals upon cytostatics administration is topical and has great ...of tumor-bearing rats with ordinary (t8) and resistant to cisplatin (t8*) Guerin’s carcinoma upon ...
7
Diffusion-weighted magnetic resonance imaging using a preclinical 1 T PET/MRI in healthy and tumor-bearing rats
... Histopathologic findings in our study revealed varying levels of inflammation in the liver parenchyma of tumor bearing rats. As histomorphology is better preserved in formalin-fixed tissues, ...
11
Generation of superoxide anion-radical in the liver monooxygenase system of preliminary radiation-exposed tumor-bearing rats
... It is shown that the increased NADPH-cyto- chrome P-450 reductase activity is accompanied with the intensification of superoxide anion-radical generation in liver microsomal fraction of prelimi- nary radiation-exposed ...
8
Suppression of acute and chronic inflammation in tumor bearing rats
... Data shown in Table animals with malignant tumors there is a broad defect VII indicate that the presence of serum from seven in expression of the inflammatory response, involving normal [r] ...
11
Normalization of hypercalcemia associated with a decrease in renal calcium reabsorption in Leydig cell tumor bearing rats treated with WR 2721
... associated with a marked increase in urinary Ca excretion, indicating an inhibition of TRCa. The elevated urine cyclic AMP of LCT-bearing rats, however, was not altered by WR-2721 treatment. These results ...
5
The effect of intranasally administered TLR3 agonist larifan on metabolic profile of microglial cells in rat with C6 glioma
... c6-glioma bearing rats after treat- ment with ...and tumor-suppressive) microglia activation [38, ...by tumor-derived factors [35, ...glioma-bearing rats in comparison with ...
10
EVALUATION OF THE ANTICARCINOGENIC EFFECT OF SOME PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR LIGANDS ON DIMETHYLBENZ (α) ANTHRACENE INDUCED MAMMARY TUMOR IN FEMALE RATS
... mammary tumor-bearing rats with fenofibrate, pioglitazone or omega-3, significantly decreased the steep increase of tumor growth rate as compared to the untreated mammary ...
22
Asn-Gly-Arg-modified polydopamine-coated nanoparticles for dual-targeting therapy of brain glioma in rats
... for tumor growth, progression, and invasion and are established hallmarks of the malignancy degree of gliomas ...Numerous tumor cells depend on endothelial cells for their survival and ...the tumor ...
16
<p>Efficacy and safety of intraperitoneally administered resveratrol against rat orthotopic ovarian cancers</p>
... Untreated tumor-bearing rats showed weight loss and a full abdomen in comparison with their healthy ...in rats of the two treatment groups but the degrees were less signi fi ...average ...
12
Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation
... on tumor cellular metabolism, penetrating across the blood–brain barrier, as well as having potential antitumor activity on brain tumors, the purpose of this study is to investigate the antitumor activity of DCA ...
10
Checkpoint blockade in solid tumors and B-cell malignancies, with special consideration of the role of CD200
... Abstract: In the ontogeny of a normal immune response, a series of checkpoints must be overcome to ensure that unwanted and/or harmful self-directed activation responses are avoided. Many of the molecules now known to be ...
9
The Effects of WW2/WW3 Domains of Smurf2 Molecule on CD4+CD25+/CD4+ Proportion in Spleen of 4T1 Tumor Bearing BALB/c Mice
... in tumor microenvironment and is the reason for the aberrant number of Tregs in tumor-bearing ...the tumor-bearing mice that received WW2/WW3 protein treatment and those of the control ...
6
Original Article The construction of EpCAM/vimentin-PLGA/lipid immunomagnetic microspheres and the isolation of circulating tumor cells from lung cancer
... the 15 patients with lung cancer were statisti- cally analyzed, and the results revealed that the positive rate of combined application of the two kinds of magnetic spheres was 95%, signifi- cantly higher than that of ...
10
Renal Clearable Ru-based Coordination Polymer Nanodots for Photoacoustic Imaging Guided Cancer Therapy
... Ru-Phen CPNs show strong NIR absorbance with an extremely high photothermal conversion efficiency measured to be ~ 60.69 %, which is the highest record among the previously reported photothermal agents. As the results, ...
11
Biochemical studies on the effects of tumor-bearing in the host rat
... (Table 2) or in animals lacking in s u lin (Manjeshwar z t a Z ., 1965). Therefore, by comparison o f the enzyme a c t i v i t y changes observed in starved ra ts (Table 2) and the changes demonstrated in host tissue s o ...
253
IN VITRO AND IN VIVO ANTI CANCER ACTIVITY OF METHANOLIC EXTRACT OF TECOMA STANS FLOWERS
... EAC tumor bearing mice was assessed by the parameters such as tumor volume, tumor weight, viable and non viable cell count, mean survival time and % increase of life span, average increase in ...
6
Chemo-immunotherapy induces tumor regression in a mouse model of spontaneous mammary carcinogenesis
... regressing tumor masses undergoing CTX + ACT/ IS but not in resilient tumors receiving single treatments, strongly suggests that the immune-enhancing effect of CTX pretreatment followed by ACT/IS may be explained, ...
12