tumor formation
Gangliosides shed by tumor cells enhance tumor formation in mice
... of tumor cell membrane gangliosides in tumor formation was probed using a series of cloned murine AKR lymphoma cell ...lines. Tumor formation was directly related to high expression and ...
5
ADAM17 in tumor associated leukocytes regulates inflammatory mediators and promotes mammary tumor formation
... stage tumor formation, suggest the importance of the Cox-2 pathway during early stages of tumor ...the formation of early stage hyperplasias [28, ...of tumor formation and that ...
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MATHEMATICAL MODEL ON DNA MUTATION AND TUMOR FORMATION
... At the early stage of the replication error without repair, it is easy to see that the change in the cell population is minimal, but gets flying so high subsequently. The higher the error during cell division, the ...
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Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation
... study found that the incidence of tumors in oophorectomized mice at 4 months post-surgery was much lower than that in sham controls. However, pre-administration of tamoxifen, which is a well-known anticancer drug used to ...
14
Cissus quadrangularis inhibits tumor formation during 7, 12-dimethylbenz (a) anthracene induced oral carcinogenesis
... the tumor preventive potential of the ethanolic extract of Cissus quadrangularis leaves (CqELet) in 7,12-dimethylbenza(a)nthracene (DMBA) induced hamster buccal pouch ...The tumor preventive efficacy of ...
5
Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis
... control tumors had typical expression of K5 (a marker of basal/myoepithelial cells) restricted to the periphery of the epithelium, whereas cKO tumors had K5 positive cells in the stroma surrounding the tumors (Figure ...
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DNA MUTATION AND TUMOR FORMATION II: ANALYSIS OF FORMULATED MODEL
... this tumor growth enhancing factors in our system at all times although many of these can be ...of tumor but do not have the power to stop its ...which tumor may develop in an ...
13
overexpression in transgenic mice and amelioration of tumor formation by miR-16
... The primary cause of pulmonary cancer consists of gene mutations induced by carcinogens contained in items, such as the cigarette smoke inhaled by long-term addicts or environmentally polluted air. The number of the gene ...
17
The role of Hes genes in intestinal development, homeostasis and tumor formation
... reduce tumor cell proliferation and induce the differentiation of tumor cells into all types of intestinal epithelial ...induce tumor cell ...
12
THE Ah LOCUS: BIOCHEMICAL BASIS FOR GENETIC DIFFERENCES IN BRAIN TUMOR FORMATION IN MICE
... Studies with B6, D2 and C3H inbred strains, and offspring from the appropri- ate genetic crosses thereof, have shown that allelic differences at the Ah locus are associated with MC[r] ...
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Stability of polyoma DNA sequences and virus-coded proteins during tumor formation.
... persistence of Py virus large T Ag during passage in vivo is emphasized by the finding that even cell lines established from tumors induced by the inoculation of weanling rats with eithe[r] ...
7
Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer- associated fibroblast accumulation
... that tumor formation was significantly reduced in CCR5-deficient mice compared with WT mice when colon 26 cells were injected into the cecal wall ...the tumor sites by quantitative reverse ...
11
The role of TGF-β/SMAD4 signaling in cancer
... initiate tumor formation, but can promote tumor progression initiated by other genes, such as KRAS activation in pancreatic duct adenocarcinoma and APC inactivation in colorectal ...
13
Functions and therapeutic roles of exosomes in cancer
... including Tumor suppressor gene 101 (Tsg101), Heat-shock protein 70 (Hsp70), and the tetraspanins CD9, CD63, and CD81, while others seem to be specific to cell and tissue ...in tumor formation. ...
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FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21
... Results: The expression of FBXO22 in HCC tissues was significantly higher than in normal liver tissues. The overall survival rate and disease-free survival time of patients with high expression of FBXO22 were ...
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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
... favor tumor formation (promotion ...oncogenes, tumor suppressor genes, and other key regulators of cell proliferation), the promo- tion stage, in which many cell types interact via secreted factors, ...
11
Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells
... Human endogenous retrovirus type K (HERV-K) Env protein was previously demonstrated to be overexpressed in human breast cancer (BC) cells and tissues. However, the molecular pathways driving the specific alterations are ...
25
HDAC9 promotes glioblastoma growth via TAZ-mediated EGFR pathway activation
... and tumor formation in ...promotes tumor formation of glioblastoma via TAZ-mediated EGFR pathway activation, and provide the evidence for promising target for the treatment of ...
13
Inhibition of nuclear factor-κB signaling suppresses Spint1 deletion-induced tumor susceptibility in the Apc Min/+ model
... accelerated tumor formation both in an inflammation-associated mice colon carcinogenesis model and in a mutant Apc model ...increased tumor formation in HAI-1-deficient mice is still ...
9
Primary acantholytic squamous cell carcinoma of the cecum: a case report
... in tumor formation and especially suspected was Lynch ...of tumor- infiltrating lymphocytes and especially presence of intraepithelial T-lymphocytes could identify the majority of colorectal cancers ...
5