tumor growth factor-β
Study the Expression of Tumor Growth Factor β (TGF β) in Mice Organs after Exposure to Aflatoxin B1 using Immunohistochemistry Technique
... Because of the high toxicity and carcinogenicity to human and animals, many countries and regulatory agencies impose strict limits on aflatoxins [1, 2]. TGF-β was originally named because of its ability to ...
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A gene therapy induced emphysema model and the protective role of stem cells
... endothelial growth factor receptor 2 and tumor growth factor β-1, and down-regulating inflammatory response, cell apoptosis and excessive pro- tease expression ...
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Original Article The overexpression of PDGF-BB and its receptor is correlated with lymphatic metastasis in patients with non-small cell lung cancer
... promoted tumor cell proliferation and metastasis but also secreted cytokines such as PDGF to facilitate lymphangiogenesis and lymphatic ...Malignant tumor tissues could activate PLTs and induce thrombotic ...
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Transforming Growth Factor – β and Glioma
... the tumor suppressive effects mentioned above one might speculate that this will help prevent the formation of more malignant cancer cells, however this not so true due to the fact that most of the more malignant ...
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Transforming growth factor β and breast cancer: Transforming growth factor β/SMAD signaling defects and cancer
... several tumor cell lines derived from neuroblastoma, melanoma and prostate cancer ...TGF- β signaling warrants closer investiga- tion of this ...TGF- β in breast ...
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Transforming growth factor β stimulates nerve growth factor production in osteoarthritic synovium
... Nerve growth factor (NGF) is a neurotrophin that modulates ...including tumor necrosis factor (TNF)-α and interleukin (IL)-1β, in mouse and human articular chondrocytes, synovial fi- ...
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Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition
... Transforming growth factor-β (TGF-β) is a key regulatory cytokine that has proinvasive and stemness-maintaining autocrine properties in glioblastoma and confers immunosuppression to the ...
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Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial to mesenchymal transition
... the tumor micro- environment ...transforming growth factor (TGF)-β) primary tumor cells may undergo epithelial-to-mesenchymal transition (EMT), a process where cells suppress E-cadherin ...
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TGF-β in pancreatic cancer initiation and progression: two sides of the same coin
... the tumor burden, abdominal metastases, and improves survival of metastatic pancreatic cancer in a murine model ...hepatocyte growth factor produced by ...
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Transforming growth factor beta and breast cancer: Tumor promoting effects of transforming growth factor β
... TGF- β production in vivo may enhance migration of tumor cells and metastatic ...independent growth in vitro, as well as increased metastases in vivo, all of which can be blocked with neutralizing ...
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The uncertain role of unmodified mesenchymal stem cells in tumor progression: what master switch?
... (FBS). Growth factors such as basic fi broblast growth factor (bFGF) are some- times added to keep the MSCs undiff ...recombinant growth factors such as platelet-derived growth ...
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Pro-inflammatory activity of Astronium fraxinifolium Schott on Lipopolysaccharide-stimulated RAW 264.7 cells
... (NO), tumor necrosis factor alpha (TNF-α), and transforming growth factor beta (TGF-β) levels were determined in supernatants from LPS-stimulated RAW ...
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Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies
... consequently tumor cell proliferation and angiogenesis ...and tumor growth in vitro and in vivo ...inhibits tumor progression of bladder carcinoma and multiple myeloma xenografts in mice by ...
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Original Article Effects of insulin-like growth factor 2 and its receptor expressions on corneal repair
... Real-time PCR was used to describe cytokine expressions in various corneal tissues at differ- ent time points (0, 3, 6, 12, 24 hours after sur- gery). As shown in Figure 2, expressions of EGF, FGF-β, KGF, HGF, ...
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Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats
... Results: In rats treated with BL, levels of transforming growth factor-b1 (TGF-b1) and tumor necrosis factor-a (TNF- a) were significantly elevated (P = 0.05 and P = 0.005). Hydroxyproline was ...
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The Role of Cytokine Interleukin 2, Transcription Factor of FoxP3 in the Immunological Regulation of Allergic Rhinitis
... The biological activity of IL-2 is to grow, maintain survival, and as a differen- tiation factor of T cells that play an important role in responding and controlling the immune response. Because of this, IL-2 is ...
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The multi-faceted functioning portrait of LRF/ZBTB7A
... oncosuppressive factor by affecting specific cell processes (proliferation, apoptosis, invasion, migration, metastasis, etc) in opposed ways, depending on cancer type and molecular ...
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Tumor-induced osteomalacia due to a recurrent mesenchymal tumor overexpressing several growth factor receptors
... derived growth factor type A; PDGFRB, platelet-derived growth factor receptor type B, VEGFR3, vascular endothelial growth factor receptor 3; PBMCs, peripheral blood ...
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Fat extract promotes angiogenesis in a murine model of limb ischemia: a novel cell-free therapeutic strategy
... Over the past decade, efforts in using adipose tissue-mediated regenerative therapies have focused on ADSCs. Mechanistic studies of ADSC-based therapy have shown that paracrine secretion is responsible for its thera- ...
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Genetic analysis of female infertility with the effect of human bmp15 and gdf9 genes: a review
... related β) super family: growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) originates from oocytes are played a very ollicle growth and these two genes ...
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