tumor necrosis factor-α
The activation of EGFR promotes myocardial tumor necrosis factor-α production and cardiac failure in endotoxemia
... as tumor necrosis factor-α (TNF-α), interleukin (IL)-1, IL-6, and IL-8 ...major factor responsible for myocardial depression during endotoxemia and cardiomyocytes are the major ...
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Efficacy and Safety of Anti-Tumor Necrosis Factor-Α Biosimilars in Rheumatological Practice and Their Registration, Patenting
... anti-tumor necrosis factor-α biosimilars, as well as their registration and ...anti-tumor necrosis factor-α biosimilars may be more accessible to the general ...
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Tofacitinib for the treatment of tumor necrosis factor α inhibitor refractory esophageal Crohn’s disease: a case report
... and tumor necrosis factor-α (TNF-α) inhibitors if the disease is more refrac- tory; both options have been described in several case series with success [2, 6, ...
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Serum Leptin, Adiponectin and Tumor Necrosis Factor-α in Hyperlipidemic Rats with/without Concomitant Diabetes Mellitus
... and tumor necrosis factor-α (TNF-α) levels are different in di- abetic and obese individuals compared with nondiabetic, nonobese ...
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The protective or damaging effect of Tumor necrosis factor-α in acute liver injury is concentration-dependent
... as tumor necrosis factor-α (TNF-α), which mediate inflammation and repair in physiologi- cal conditions ...[12]. Tumor necrosis factor-α is a mul- ...
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Tumor necrosis factor α sensitizes spinal cord TRPV1 receptors to the endogenous agonist N-oleoyldopamine
... Coexpression of mRNA for TNFR1 and TRPV1 recep- tors [17] and colocalization of TNFR1 and TRPV1 immunoreactivity [29] in DRG neurons has been reported. Long-term application of TNF a (48 h) increases the number of TRPV1 ...
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Influence of depression symptoms on serum tumor necrosis factor α of patients with chronic low back pain
... Introduction: Patients with chronic low back pain (cLBP) have high rates of comorbid psychiatric disorders, mainly depression. Recent evidence suggests that depressive symptoms and pain, as interacting factors, have an ...
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Tumor necrosis factor α induced adipose related protein expression in experimental arthritis and in rheumatoid arthritis
... of tumor necrosis factor-induced adipose-related protein in splenocytes of arthritic mice To explore TNF-related genes in GPI-induced arthritis, we per- formed GeneChip analysis using arthritic ...
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Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patients
... 9. Lowes MA, Chamian F, Abello MV, Fuentes-Duculan J, Lin SL, Nussbaum R, Novitskaya I, Carbonaro H, Cardinale I, Kikuchi T, Gilleaudeau P, Sullivan- Whalen M, Wittkowski KM, Papp K, Garovoy M, Dummer W, Steinman RM, ...
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A role for tumor necrosis factor-α in ischemia and ischemic preconditioning
... growth factor) and vascular endothelial growth factor (VEGF) induced neuroprotection against glucose deprivation, NMDA excitotoxicity and oxygen glucose deprivation and that these effects required the ...
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Incidences of Serious Infections and Tuberculosis among Patients Receiving Anti Tumor Necrosis Factor α Therapy
... Purpose: Anti-tumor necrosis factor-alpha (TNF-α) medications represent a major advancement in the management of chronic inflammatory diseases. However, these agents are associated with ...
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Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease
... ymorphism, a tendency for a difference in genotype fre- quency between COPD patients and controls was observed (p = 0.019), which was due to enhanced GA fre- quency in the patient group. No differences were obtained for ...
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Functional Analysis of a Human Tumor Necrosis Factor α (TNF-α) Promoter Polymorphism Related to Joint Damage in Rheumatoid Arthritis
... (1997) Scarring trachoma is associated with polymor- phism in the tumor necrosis factor alpha (TNF-a) gene promoter and with elevated TNF-a levels in tear fluid. Grove J, Daly AK, Bassen[r] ...
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Invasive Salmonellosis by the Very Rare Salmonella choleraesuis in a Returning Traveler on a Tumor Necrosis Factor-α Inhibitor
... This case report describes the somewhat unusual clinical presentation of Salmonella choleraesuis when compared to other nontyphoidal salmonellosis. Whereas most other non- typhoidal salmonellae cause self-limited ...
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Association between tumor necrosis factor-α gene polymorphisms and hepatitis B virus infection in Iraqi Patients
... patients were firstly diagnosed and none of them was under therapy. In addition to patients, 24 apparently healthy Iraqi Arab subjects were included as a control sample in the study (6 males and 18 females), and their ...
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Expression of tumor necrosis factor-α and interleukin-1β genes in the cochlea and inferior colliculus in salicylate-induced tinnitus
... Linear regression analysis showed that tinnitus scores were positively associated with gene expression level of NR2B and with gene expression levels of TNF-a and IL-1b in cochlea and IC [r] ...
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Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure
... Because 60% (39/65) of mice with LPS/D-GalN-induced ALF died within 12 h and displayed serum biochemical markers and liver morphology consistent with liver failure, we chose a 12-h time point to assess the effect of ...
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Successful Treatment of Bronchiolitis Obliterans in a Bone Marrow Transplant Patient With Tumor Necrosis Factor-α Blockade
... these, tumor necrosis factor- ␣ (TNF- ␣ ), a mesenchymal growth factor that is known to partic- ipate in matrix remodeling, has been shown to be elevated in the early stage of BO in human and ...
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Matrix metalloproteinase 7–dependent release of tumor necrosis factor α in a model of herniated disc resorption
... effect of MMP-7 was specific for the release and not the synthesis of TNF-α, because there was no significant effect of MMP-7 on the levels of cell-surface TNF-α in the presence or absence of a protein ...
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THE EFFECT OF OPHIOCEPHALUS STRIATUS EXTRACTS ON TUMOR NECROSIS FACTOR-α (TNF-α) SERUM IN CANCER CACHEXIA PATIENTS
... Ophiocephalus striatus extract. Before treatment, TNF-α average plasma level was 7.83 pg/mL and decreased to 3.82 pg/mL after treatment. Wilcoxon test used in this study showed highly significant decrease in ...
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