Tumor necrosis factor-alpha production
Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production
... IFN production could also explain the differences seen in viral replication between THP-1-derived M and MDM, as type I IFN production was almost absent in THP-1- derived M ... production in ...
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African Swine Fever Virus Infection Induces Tumor Necrosis Factor Alpha Production: Implications in Pathogenesis
... the production of tumor necrosis factor alpha (TNF- a ) induced by in vitro infection with African swine fever (ASF) virus (ASFV) and the systemic and local release of this inflammatory ...
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Regulation of Interleukin-8 by Interleukin-10 and Transforming Growth Factor β in Human Monocytes Infected with Mycobacterium bovis
... including tumor necrosis factor alpha, interleukin 1 (IL-1), and ...chemotactic factor for neutrophils (11, 12, ...growth factor  ...cytokine production by li- ...
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Relevance of Gamma Interferon, Tumor Necrosis Factor Alpha, and Interleukin-10 Gene Polymorphisms to Susceptibility to Mediterranean Spotted Fever
... cytokine production patterns, clearly indicating their role in the immunomodulation of the response against the microorganism, and the differences in cytokine production seem to influence the extent and ...
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In vitro cytokine production by normal human peripheral blood mononuclear cells as a measure of immunocompetence or the state of activation.
... In the present study, normal ranges for the in vitro production by PBMCs of interleukin-1l (IL-1i), tumor necrosis factor alpha (TNF-o), IL-2, and gamma interferon (IFN--y) were establis[r] ...
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The role of tumor necrosis factor alpha in systemic lupus erythematosus
... diminished production of TNF, a defect stemming from the otherwise healthy NZW parent, and proved that NZB/W disease was at least partly reversible by administration of recombinant TNF early in ...
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Racial differences in tumor necrosis factor-α-induced endothelial microparticles and interleukin-6 production
... HUVECs were purchased from Lonza Inc (Walkersville, MD), who harvested ECs from umbilical cord donors (AA, n = 3; Caucasian, n = 3). Cryopreserved HUVECs were then shipped by Lonza as frozen primaries. The HUVECs were ...
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Natural Killer Cells and Antifungal Host Response
... ing factor) and RANTES (regulated upon activation, normal T-cell expressed, and secreted; chemokine ligand 5), which augment the immune response by phagocytes and T cells, re- spectively (45, 46, ...upregulate ...
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The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infection
... IL-10 production and low level of IL-12 ...IL-10 production as well as transi- ent expression of tumor necrosis factor alpha (TNF-α) ...
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TUMOR NECROSIS FACTOR ALPHA AND INTERLEUKIN 6 IN ESSENTIAL HYPERTENSION
... Increased production of tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) which might play an important role in the initiation and progression of hypertension by a variety of ...
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Pattern of cytokines and pharmacomodulation in sepsis induced by cecal ligation and puncture compared with that induced by endotoxin.
... The production of tumor necrosis factor alpha (TNF- a ), interleukin-1 b (IL-1 b ), and IL-6 and their phar- macomodulation were evaluated in a model of polymicrobial sepsis induced in ...
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Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells Cytokine mRNA and protein kinetics, and cellular distribution
... tophaceous material from a patient with gout contained significant levels of TNF alpha and cells cultured from the tophus produced TNF alpha in vitro. In rheumatoid synovial cells, spontaneous release of ...
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Tumor Necrosis Factor-alpha (-308 G/A) is a Predictor for Development of Gestational Diabetes Mellitus in Saudi Pregnant Women
... The production of TNFα is monitoring and is affecting by a polymorphism, −G308A, and also, the TNFα gene is position within the grade III area of the main histocompatibility complex on the little arm of chromosome ...
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Tumor necrosis factor alpha upregulates human microglial cell production of interleukin-10 in vitro.
... 11). Production of TNF-a by activated microglia plays a key role in the generation of nitric oxide, a free radical with neurotoxic activity (10, ...a production by somatic mac- rophages (3, 18), endogenous ...
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Contribution of tumor necrosis factor alpha to the pathogenesis of stroke
... TNF- alpha has been found both in the astrocyte end-feet and in ependymal cells which suggests the involve- ment of this cytokine in the blood-brain barrier dam- age mechanism ...TNF- alpha expression in ...
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The effect of the pro inflammatory cytokine tumor necrosis factor alpha on human joint capsule myofibroblasts
... The antiproliferative impact of TNF-Į in human HSCs, the MFs of the liver, was previously described to be medi- ated by increased formation of nuclear factor-kappa-B (NF- țB) DNA-binding complexes [29]. ...
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Participation of the cytokines interleukin 6, tumor necrosis factor alpha, and interleukin 1 beta secreted by acute myelogenous leukemia blasts in autocrine and paracrine leukemia growth control
... autocrine production of colony-stimulating factors ...IL-6, tumor necrosis factor (TNF)-alpha, and IL-1, products of cells of the myeloid lineage, are known to be involved in growth ...
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Targeting Mycobacterium tuberculosis Tumor Necrosis Factor Alpha Downregulating Genes for the Development of Antituberculous Vaccines
... TNF production and that this can lead to modulation of virulence (14, ...the production of anomalous mycolic acid species as well as in aberrant cell colony morphology and envelope architecture ...
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Epinephrine inhibits tumor necrosis factor alpha and potentiates interleukin 10 production during human endotoxemia
... Whole blood stimulation. On day 1 (0, 4, and 8 h) and day 2 ( 2 3 and 0 h), blood was drawn to assess the effect of various durations of epinephrine infusion on endotoxin responsiveness in human whole blood. Blood was ...
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Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin 25 Mediated Protection from Amebic Colitis
... ABSTRACT The parasite Entamoeba histolytica is a cause of diarrhea in infants in low-income countries. Previously, it was shown that tumor necrosis factor alpha (TNF- ␣ ) production was ...
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