Tumor necrosis factor (TNFα)
Increased serum levels of tumor necrosis factor α and interluekin 6 in adult Bahraini sickle cell disease patients with Hypovitaminosis d and low bone mineral density
... inhibiting tumor necrosis factor-α (TNF-α)-induced NF-κB activation, as well as TNF-α-induced VCAM-1 expression (Kudo et ...control TNFα-induced synovial inflammation (van Hamburg et ...
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Tumor necrosis factor can induce fever in rats without activating protein breakdown in muscle or lipolysis in adipose tissue
... Tumor necrosis factor (TNF, cachectin) is a macrophage product that has been suggested to signal the loss of body weight, the decrease in adipose tissue and muscle mass, and anorexia during ...
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The impact of metallothionein II on microglial response to tumor necrosis factor alpha (TNFα) and downstream effects on neuronal regeneration
... of tumor necrosis factor (TNF)-α-treated microglia via the LRP1 receptor and that this action of MTII upon microglia causes them to become a more permissive substrate to sup- port axonal outgrowth in ...
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Tumor necrosis factor-alpha and Fas/Fas ligand signaling pathways in chronic spontaneous urticaria
... for Tumor Necrosis Factor alpha (TNF- α)—Quantikine ELISA Human TNF-α kit, for Fas— Quantikine ELISA Human Fas/TNFRSF6 kit, for Fas Ligand (FasL)—Quantikine ELISA Human Fas Ligand/ TNFSF6 kit, for ...
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Cachectin/Tumor Necrosis Factor
... synthesized tumor necrosis factor, agonist peptide TNF (70-80) and demonstrated that it enhanced the human PMN-mediated killing of plasmodium falciparum in vitro and reduced the plasmodium chabaudi ...
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Effect of Tumor Necrosis Factor on Body Systems
... Tumor necrosis factor-alpha (TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase ...
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Treatment with recombinant human tumor necrosis factor alpha protects rats against the lethality, hypotension, and hypothermia of gram negative sepsis
... Treatment with recombinant human tumor necrosis factor-alpha protects rats against the lethality, hypotension, and hypothermia of gram-negative sepsis.. Tumor necrosis factor TNF is a pe[r] ...
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Cellular Responses to Tumor Necrosis Factor
... Tumor necrosis factor α (TNF) is a proinflammatory cytokine produced mainly by activated macrophages or monocytes and plays an important role in diverse cellular events, such as the production of ...
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Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin 25 Mediated Protection from Amebic Colitis
... ABSTRACT The parasite Entamoeba histolytica is a cause of diarrhea in infants in low-income countries. Previously, it was shown that tumor necrosis factor alpha (TNF- ␣ ) production was associated ...
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Tumor necrosis factor alpha inhibits stem cell factor induced proliferation of human bone marrow progenitor cells in vitro Role of p55 and p75 tumor necrosis factor receptors
... interactions between TNF-alpha and SCF. Here, we demonstrate that TNF-alpha potently and directly inhibits SCF-stimulated proliferation of CD34+ hematopoietic progenitor cells. Furthermore, TNF-alpha blocked all colony ...
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Acute and probable chronic Q fever during anti TNFα and anti B cell immunotherapy: a case report
... Case presentation: A 71-year-old Caucasian male was diagnosed with symptomatic acute Q fever (based on positive C. burnetii PCR followed by seroconversion) while using anti-tumor necrosis factor- α ...
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Targeting tumor-necrosis factor receptor pathways for tumor immunotherapy
... Subsequent to CTLA-4, PD-1 was also shown to regulate the immune response. PD-1 interacts with B7-homolog 1 (B7-H1 or programmed death receptor-1 ligand1 [PD-L1]) and B7-DC (PD-L2) on APCs and tumor cells. ...
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Prolonged mechanical ventilation–induced neuroinflammation affects postoperative memory dysfunction in surgical mice
... Many studies have been focused on the lung–brain axis with the purpose of determining which factors im- plicated in acute lung injury [5] and in its ventilatory management can give rise to the appearance of cognitive ...
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Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet activating factor
... necrosis of the gastrointestinal tract. The morphological changes of TNF-induced bowel lesions are indistinguishable from those caused by PAF. The mechanism of TNF-induced bowel necrosis is unclear. In the ...
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Comparative effectiveness and safety of rituximab versus subsequent anti–tumor necrosis factor therapy in patients with rheumatoid arthritis with prior exposure to anti–tumor necrosis factor therapies in the United States Corrona registry
... (rheumatoid factor (RF) seroposi- tivity, duration of RA, American Rheumatism Associ- ation functional class, tender and swollen joint counts, patient and provider global assessments, patient pain and functional ...
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Characterization in vitro of a human tumor necrosis factor binding protein A soluble form of a tumor necrosis factor receptor
... Results from biosynthetic labeling of cells with 35S-cysteine followed by immunoprecipitation with anti-TNF-BP indicated that TNF-BP is formed and released at the cell surface by cleavag[r] ...
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Targeting Mycobacterium tuberculosis Tumor Necrosis Factor Alpha Downregulating Genes for the Development of Antituberculous Vaccines
... TNF is arguably the best-established antimycobacterial immuno- logical factor in humans, as reflected by the enhanced susceptibil- ity to M. tuberculosis infection of individuals treated with TNF blockade therapy ...
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The role of progranulin in diabetes and kidney disease
... TNFR: tumor necrosis factor receptor; TNFα: tumor necrosis factor-α; BMI: body mass index; MCP-1: monocyte chemoattractant protein-1; CRP: C-reactive protein; IL-6: ...
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Inhibition of IRE1 modifies effect of glucose deprivation on the expression of TNFα-related genes in U87 glioma cells
... transcription factor that stimulates the expression of numerous UPR-specific genes, namely other key transcription factors [14, ...by tumor necrosis factor (TNF) and its receptors signaling, ...
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Surfactant gene polymorphisms and interstitial lung diseases
... Pantelidis P, Fanning GC, Wells AU, Welsh KI, du Bois RM: Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymor- phisms[r] ...
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