Tumor Progression
Chemokines in tumor progression and metastasis
... of tumor progression. Chemokines and their receptors facilitate tumor growth by promoting EMT as well as ...in tumor progression and ...mediate tumor progression and ...
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Role of DKK4 in Tumorigenesis and Tumor Progression
... Studies of DKK4 expression identified that binding of TR to nucleotides 1645-1629 of promoter of DKK4 gene is related to T3-dependent DKK4 transcription. Triiodothyronine (T3) and TR up- regulate the level of DKK4 to ...
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Remodeling of calcium signaling in tumor progression
... in tumor progression in vivo has been revealed in breast and cervical cancer ...in tumor growth and angiogenesis in vivo ...for tumor metastasis [70]. Through these vessels, tumor cells ...
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TGF- Sustains Tumor Progression Through
... cells like cancer associated fibroblasts to inhibit tumor progression and metastasis at early stages of 53.. disease ( 13 ).[r] ...
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TRIM28 is overexpressed in glioma and associated with tumor progression
... Many studies have investigated the correlation between TRIM28 and tumor malignance and progression. Several studies demonstrated that TRIM28 overexpression was always associated with clinicopathological ...
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Role of Urokinase Receptor in Tumor Progression and Development
... Many tumor-promoting effects of uPAR occur independently from the proteolytic ...vivo tumor development by suppressing Notch 1-pertinent gene expression and signaling events ...promote tumor ...
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Neutrophils drive accelerated tumor progression in the collagen dense mammary tumor microenvironment
... a tumor-associated neutrophil (TAN) population analo- gous to ...of tumor growth are more cytotoxic to tumor cells by either directly killing tumor cells or by secreting reactive oxygen ...
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Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma
... This study was approved by the institutional review board of Mie University Hospital, and written informed consent was obtained from all patients. We also acquired a written informed consent from a parent or a legal ...
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CKAP4 is a Dickkopf1 receptor and is involved in tumor progression
... dependent AKT activity, migration, and proliferation ability of S2-CP8, A549, SUIT-2, and HepG2 cells in vitro. The anti-CKAP4 antibody also suppressed xenograft tumor formation by S2-CP8 and A549 cells. In ...
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CD44 is overexpressed and correlated with tumor progression in gallbladder cancer
... To further evaluate the relationship between CD44 expression and clinicopathological characteristics in GBC, we found that upregulated CD44 was significantly correlated to GBC TNM stage (III and IV vs I and II, P = ...
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A role for pre-mNK cells in tumor progression
... present tumor antigens [3, ...hibit tumor immunity through adaptive resistance mecha- nisms [29, 30] as well as to be involved in controlling chronic infections and autoimmunity ...in tumor-bearing ...
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Proposal of a hybrid approach for tumor progression and tumor-induced angiogenesis
... towards tumor, how is diffused from vessels to tumor, how tumor cells may control blood flow and oxygen delivery, among ...from tumor cells may enhance tube formation capac- ity of that ...
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Tumor-associated macrophages: an accomplice in solid tumor progression
... primary tumor to create a metastatic colony ...of tumor cells depends on the ...facilitate tumor cell invasion and migration by secreting matrix metalloproteinases, serine proteases, and cathepsins ...
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Cancer Progression Related with Tumor associated Macrophages
... cancer progression. Tumor cell-derived factors highjack the regular functions of macrophages and induce M2 macrophage phenotype that are known as ...in tumor promotion, and commonly known as ...the ...
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<p>Clinical Applications of Cerebrospinal Fluid Circulating Tumor DNA as a Liquid Biopsy for Central Nervous System Tumors</p>
... the progression of CNS lesions, but histopathology results of the resected lesions revealed that all the changes might have been in fl ammatory effects rather than true tumor ...true progression of ...
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A cytokine mediated link between innate immunity, inflammation, and cancer
... microenvironment that is an indispensable participant in the neoplastic process. The mechanisms that link infection, innate immunity, inflammation, and cancer are being unraveled at a fast pace. Important components in ...
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Effects of hyperglycemia on the progression of tumor diseases
... activate tumor cells’ response to anticancer drugs ...and tumor cell apoptosis ...and tumor suppressor genes in humans are mutually restricted in controlling cell growth, but when mutated or ...
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The roles of mesenchymal stem cells in tumor inflammatory microenvironment
... by tumor cells. Studies have demonstrated that a variety of non-tumor cells in the tumor microenvironment affect tumor behavior; thus, a new focus of cancer research has been the development ...
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Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles
... advanced tumor stage (Figure ...malignant progression and the intensity of its expression was inversely related to tumor grade, possibly suggesting that alterations in L3 expression promote ...
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Comparative evaluation of a novel, moderately hypofractionated radiation protocol in 56 dogs with symptomatic intracranial neoplasia
... Attempts to shorten radiation protocols for intracranial tumors in dogs by reducing fraction number drastically, while maintaining an adequate total dose, have been made but hypofractionated treat- ments have not reached ...
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