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Tumor Relapse

miR-181c associates with tumor relapse of high grade osteosarcoma

miR-181c associates with tumor relapse of high grade osteosarcoma

... and tumor cell proliferation and is associated with high grade osteosarcoma [9, 36, 42-45] ...the tumor relapse, can be partially explained considering that among its putative targets figure genes ...

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Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma

Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma

... of tumor relapse, following chemotherapeutic treatment is very difficult, especially because of inter- and intra-tumoral ...differentiated tumor, suggesting a loss of the EMT and favoring the ...

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EMT, CTCs and CSCs in tumor relapse and drug-resistance

EMT, CTCs and CSCs in tumor relapse and drug-resistance

... Tumor relapse and metastasis are the primary causes of poor survival rates in patients with advanced cancer despite successful resection or chemotherapeutic ...of relapse and metastasis is the ...

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Expression of ALDH1 in breast invasive ductal carcinoma: an independent predictor of early tumor relapse

Expression of ALDH1 in breast invasive ductal carcinoma: an independent predictor of early tumor relapse

... some tumor suppressors ...and tumor stem cell differentiation, and invasion and me- tastasis in breast cancer are mediated by a cellular subcomponent with stem cell characteristics expressing ALDH1 ...play ...

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Radiation induced acid ceramidase confers prostate cancer resistance and tumor relapse

Radiation induced acid ceramidase confers prostate cancer resistance and tumor relapse

... and relapse of a proportion of radiotherapy ...earlier relapse compared with IR-treated mice with no AC induction, suggesting a significant contribution to therapy ...

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Clinical significance of Nectin-4 expression in metastasis and angiogenesis for tumor relapse

Clinical significance of Nectin-4 expression in metastasis and angiogenesis for tumor relapse

... Tumor and normal tissue samples were lysed by modified RIPA lysis buffer using tissue homogenizer. Following lysis, western blot analysis was performed as described in our earlier studies (38). Briefly, 60 µg of ...

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Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumors

Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumors

... with tumor relapse (15–20%); in these cases, overall survival decreases to 50–60% ...and relapse rates, differing only in the classification of risk ...on tumor stage and histology and is used ...

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A STUDY ON IMMUNOTHERAPY IN CANCER TREATMENT

A STUDY ON IMMUNOTHERAPY IN CANCER TREATMENT

... sustained tumor dismissal ...multivalent tumor related antigens (TAA), notwithstanding, is as yet a ...metastatic tumor relapse in a creature ...

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Accelerated whole breast irradiation in early breast cancer patients with adverse prognostic features

Accelerated whole breast irradiation in early breast cancer patients with adverse prognostic features

... The tumor-, treatment-, and toxicity-related variables were compared between the AWBI and CWBI groups using the chi-squared test, t-test, and Fisher’s exact ...breast tumor relapse (IBTR) was defined ...

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Original Article Clinicopathological features and prognosis of gastric mixed adenoneuroendocrine carcinoma

Original Article Clinicopathological features and prognosis of gastric mixed adenoneuroendocrine carcinoma

... the tumor sites showed no influ- ence on the ...stage, tumor relapse status, and dis- tant metastasis status significantly influence 1-year survival rate, while patient’s age shows no ...

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Interactive Effects of PD-L1 Expression in Tumor and Immune Cells on Prognosis of Esophageal Squamous Cell Carcinoma: A One-Center Retrospective Cohort Study

<p>Interactive Effects of PD-L1 Expression in Tumor and Immune Cells on Prognosis of Esophageal Squamous Cell Carcinoma: A One-Center Retrospective Cohort Study</p>

... Similarly, the PD-L1 expression in IC did not have an association with the lymph node metastasis, tumor stage, neural invasion or blood vessel invasion. 10,16 The PD-L1 expression in TC and IC had no relevance ...

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Delineation of radiation therapy target volumes for patients with postoperative glioblastoma: a review

Delineation of radiation therapy target volumes for patients with postoperative glioblastoma: a review

... residual tumor and cavity volumes plus 2 cm margins result in smaller volumes of normal brain receiving high-dose irradiation, compared to calculations that include expanded ...

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P53-positive expression in dysplastic surgical margins is a predictor of tumor recurrence in patients with early oral squamous cell carcinoma

<p>P53-positive expression in dysplastic surgical margins is a predictor of tumor recurrence in patients with early oral squamous cell carcinoma</p>

... the tumor biopsy specimens were diagnosed as invasive OSCC; 3) all the patients had at least an initial frozen-section dysplastic margin: mild 45, moder- ate 17, severe 10; 4) no radiotherapy or chemotherapy was ...

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Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer

Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer

... primary tumor and dis- section of the hilar and mediastinal lymph ...resected tumor tissue and lymph nodes were processed for routine histopatho- logical assessment, and the histological subtypes were clas- ...

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Expression of p-AKT characterizes adenoid cystic carcinomas of head and neck with a higher risk for tumor relapses

Expression of p-AKT characterizes adenoid cystic carcinomas of head and neck with a higher risk for tumor relapses

... Immunohistochemical staining with commercially avail- able antibodies were done in standard technique follow- ing manufacturer's protocols. Positive controls were used in accordance with manufacturer's recommendations or ...

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Host genotype and tumor phenotype of chemokine decoy receptors integrally affect breast cancer relapse

Host genotype and tumor phenotype of chemokine decoy receptors integrally affect breast cancer relapse

... of tumor specimens was carried out in the Department of Pathology in our hospital; (iii), with operable tumor and without any evidence of metastasis at diagnosis; (iv), not receiving neoadjuvant systemic ...

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Original Article Clinical efficacy and toxicity of PEG-asparaginase in patients with solid tumor and ALL: a meta-analysis

Original Article Clinical efficacy and toxicity of PEG-asparaginase in patients with solid tumor and ALL: a meta-analysis

... In conclusion, based on our results of this study, we found that PEG-asparaginase had a higher response rate and lower common side effect rate in patients with ALL compared to those in patients with solid tumor. ...

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The cost of relapse and the predictors of relapse in the treatment of schizophrenia

The cost of relapse and the predictors of relapse in the treatment of schizophrenia

... previous relapse improves the ability to predict subse- quent treatment costs over and above potential associa- tions with patients’ current level of functioning and symptomatology, we have conducted a sensitivity ...

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STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma

... each tumor type was determined by the response of the irinotecan arm; once the mice in the irinotecan arm no longer had palpable tumor, the dosing for all groups was ...while relapse in the ...

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Increased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy

<p>Increased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy</p>

... primary tumor and CTC ...metastatic relapse, whereas the detection of CTCs after NAC was signi fi cantly associated with a higher rate of metastatic ...

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