tumour cells
Improved methods using the reverse transcriptase polymerase chain reaction to detect tumour cells
... circulating tumour cells, though the clinical benefit remains ...of tumour cells after four commonly used different methods of sample ...one tumour cell spiked in 2 ml of whole blood ...
7
Adenovirus-Mediated Gene Transduction of Pancreatic Tumour Cells Lines
... pancreatic tumour cells: PSN-1, ASPC-1, Panc-1 and Capan-1 were obtained from ECACC, Salisbury, UK and recently-established human pancreatic tumour cells NP18 [18] were obtained from Dr Ramon ...
5
Both tumour cells and infiltrating T-cells in equine sarcoids express FOXP3 associated with an immune-supressed cytokine microenvironment
... the tumour, infiltrating between the fibro- blasts (Figure 1A), at higher power the T-cells had an activated blast morphology with the presence of distinct membrane staining surrounding an area of cytoplasm ...
14
A gene expression profile for detection of sufficient tumour cells in breast tumour tissue: microarray diagnosis eligibility
... the tumour sample con- tains sufficient tumour cells for ...of tumour cells to define the suitability of the ...sufficient tumour tissue will shorten the processing time for ...
8
Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells
... ZR-75.1 tumour cells correlates to the other results related to high glucose oxidation and AEC ...in tumour cells in vivo is not exclusively derived from actual glycolytic flux ...
10
Mesenchymal Stem Cells Inhibit Proliferation of Lymphoid Origin Haematopoietic Tumour Cells by Inducing Cell Cycle Arrest
... stem cells (MSC) inhibit tumour cell proliferation, thus promising a novel therapy for treating ...Jurkat tumour cells, the proliferation of tumour cells were profoundly ...
6
Gene expression of circulating tumour cells in breast cancer patients
... Materials and Methods: We performed realtime-PCR and multiplex-PCR analyses following immunomag- netic separation of CTC. Peripheral blood (PB) sam- ples of 63 patients with breast cancer of various stages were analyzed ...
7
Novel approaches in the detection and characterisation of circulating and micrometastatic tumour cells in epithelial malignancies
... defined conditions of amplification reagents were all of particular importance. However, it is now becoming clear that many of these targets may not have the requisite specificity to distinguish epithelial tumour ...
323
Heterogeneous expression of EPCAM in human circulating tumour cells from patient-derived xenografts
... circulating tumour cells in the peripheral blood and has the potential to identify novel CTC markers using PDX ...used. Tumour DNA content is more stable than RNA content, thus in principle this ...
9
Patatin like PLA2 with cytotoxicity against mammalian and plant tumour cells
... against tumour cells. One of the main differences between tumour and healthy animal cells lies in the fact that their lipid compositions and distributions are ...of tumour cells, ...
16
Circulating tumour cells in patients with urothelial tumours: Enrichment and in vitro culture
... lating tumour cells (CTCs) are frequently detected in patients with urothelial ...of tumour progression or recurrence before the onset of clinically detected ...
6
Enrichment of circulating head and neck tumour cells using spiral microfluidic technology
... Whilst locoregional control of head and neck cancers (HNCs) has improved over the last four decades, long-term survival has remained largely unchanged. A possible reason for this is that the rate of distant metastasis ...
10
Impact of label-free technologies in head and neck cancer circulating tumour cells
... circulating tumour cells, determine whether HPV-infection plays a pivotal role, and provide threshold CTC counts for HNSCC patients in order to determine patient ...
12
Demonstration of anti-tumour bystander killing with prodrug-preloaded suicide gene-engineered tumour cells: a potential improvement for cancer therapeutics
... TK+ve tumour cells would be exposed to GCV in vitro, in order to pre-load the tumour cells with GCV, wash the excess GCV away and then inject the cells for study of their in vivo ...
11
Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo
... mammary tumour progression, we initially interbred the MMTV- activated ErbB2 strain (NDL2-5) [20] with separate strains of mice bearing MMTV-Cre and conditional FAK alleles ...mammary tumour onset was ...
14
Short term ex vivo expansion of circulating head and neck tumour cells
... circulating tumour cells (CTCs) in the peripheral blood of ...circulating tumour cells through negative selection and cultured in 2D and 3D culture environments under hypoxic conditions (2% O ...
9
Modelling the interactions between tumour cells and a blood vessel in a microenvironment within a vascular tumour
... a tumour consists of a mixture of live and dead tumour cells, macrophages, extracellular water and endothelial cells (forming the tumour vasculature) embedded in a tissue ...live ...
29
Phenotypic diversity of circulating tumour cells in patients with metastatic castration-resistant prostate cancer.
... requires cells to contain a 4 0 ,6-diamidino-2-phenylindole positive (DAPI)-intact nucleus, lack expression of the haematopoietic marker CD45, express epithelial cell adhesion molecule (EpCAM) and cytokeratin ...
15
Circulating tumour cells in regionally metastatic cutaneous squamous cell carcinoma: A pilot study
... circulating tumour cells (CTCs) that are shed from the primary tumour ...space, tumour cells have the opportunity to metastasize to distant sites (Mesenchymal Epithelial ...
5
The role of glycosaminoglycans in the adhesion of tumour cells to endothelium
... the tumour cell surface, suggesting that proteins expressed by the tumour cells are involved in recognition of the endothelial ...mediate tumour cell binding to HUVEC is supported by ...
227