Two-component histidine kinase
Genetic Interactions of the E3 Ubiquitin Ligase Component FbxA with Cyclic AMP Metabolism and a Histidine Kinase Signaling Pathway during Dictyostelium discoideum Development
... a two-component histidine kinase-signaling pathway (37, ...various two-compo- nent histidine kinases also function, under particular circum- stances, as protein phosphatases, ...
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Amino acid identity at one position within the alpha1 helix of both the histidine kinase and the response regulator of the WalRK and PhoPR two component systems plays a crucial role in the specificity of phosphotransfer
... interacting surfaces, and of how phosphotransfer is effected, has been established by crystallographic and mutational analysis of many TCSs (Madhusudan et al., 1996; Tzeng & Hoch, 1997; Varughese et al., 1998; Jiang ...
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Microbiology The Essential WalK Histidine Kinase and WalR Regulator Differentially Mediate Autolysis of Staphylococcus aureus RN4220
... The two-component regulatory system, WalR/WalK is necessary for growth of different gram-positive bacteria, including Staphylococcus ...the histidine kinase protein WalK and the response ...
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Histidine Kinase Two-Component Response Regulator Proteins Regulate Reproductive Development, Virulence, and Stress Responses of the Fungal Cereal Pathogens Cochliobolus heterostrophus and Gibberella zeae
... In A. nidulans, the balance between sexual and asexual sporulation is set by light, acting through a VeA complex that includes the global regulator LaeA (10). To the extent that these regulators are conserved in the ...
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DETERMINATION OF THE INSILICO ANTIBACTERIAL ACTIVITY OF AMLODIPINE
... Histidine kinase (HK) receptors are elements of the two-component signal transduction systems(TCST) commonly found in bacteria and lower eukaryotes, where they are crucial for environmental ...
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Insight into the Role of HOG Pathway Components Ssk2p, Pbs2p, and Hog1p in the Opportunistic Yeast Candida lusitaniae
... important component of the Saccharomyces cerevisiae signaling network is the high-osmolarity-glycerol (HOG) mi- togen-activated protein kinase (MAPK) pathway, which re- sponds to osmotic, oxidative, and ...
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Split histidine kinases enable ultrasensitivity and bistability in two component signaling networks
... of kinase and phosphatase activities through free CheA3 is the underpinning mechanism of ultrasensitivity, we considered dynamics in two alternative models where such coupling is missing; (i) a bifunc- ...
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Master and Commander in Fungal Pathogens: the Two-Component System and the HOG Signaling Pathway
... sensor kinase mutants, such as the ...the histidine kinase and receiver domains are commonly found in all hybrid sensor kinases, the signaling or ligand- sensing region must lie in other subdomains ...
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Histidine Phosphotransfer Proteins in Fungal Two-Component Signal Transduction Pathways
... fungal two-component signal transduction pathways has revealed roles for these pathways in osmotic and oxidative stress responses, fungicide sensitivity, phase transition, dimorphism, secondary metabolite ...
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Altered Phosphotransfer in an Activated Mutant of the Saccharomyces cerevisiae Two-Component Osmosensor Sln1p
... SLN1 two-component signaling pathway of Saccha- romyces cerevisiae is a multistep phosphorelay system that responds to changes in osmotic conditions via the HOG1 mitogen-activated protein (MAP) ...
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Role for the Ran Binding Protein, Mog1p, in Saccharomyces cerevisiae SLN1-SKN7 Signal Transduction
... of two signal transduction modules ...(MAP) kinase pathway, is regulated by a second module known as a “two-component” phosphorelay that was first char- acterized in prokaryotes and has since ...
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2018_Knechel.pdf
... into two main domains: a histidine kinase that is part of the BaeS superfamily and a response ...other histidine kinases is whether BaeS is a transmembrane protein or confined to the ...the ...
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Systematic identification of conserved bacterial c-di-AMP receptor proteins.
... sensor histidine kinase that in many bacteria controls, together with its cognate response regulator KdpE, the expression of a second type of potassium uptake ...the two-component system ...
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Two-Component Histidine Phosphotransfer Protein Ypd1 Is Not Essential for Viability in Candida albicans
... putative histidine phosphotrans- fer ...The histidine-contain- ing phosphotransfer (HPt) domain (amino acids 26 to 125) of this protein has the characteristics of a prototypical histidine phos- ...
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Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation
... and histidine kinase/response regulator ...sensor kinase DesK, a two-component system that controls membrane fluidity in Bacillus ...to two distinct exposed surfaces of the ...
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Reversible uptake of molecular oxygen by heteroligand Co(II)–l-α-amino acid–imidazole systems: equilibrium models at full mass balance
... asparagine, histidine) which, when in aqueous solutions, activate and reversibly take up dioxygen, while maintaining the structural scheme of the heme group (imidazole as axial ligand and O 2 uptake at the sixth, ...
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Structure of the NS1 Protein N-Terminal Origin Recognition/Nickase Domain from the Emerging Human Bocavirus
... Model for recognition of HBoV1 Ori by NS1. Replication mechanisms of HBoV have not been well characterized, largely owing to lack of an animal model and difficulty in tissue culture (15). Our structural results indicate ...
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Group III Histidine Kinase Is a Positive Regulator of Hog1-Type Mitogen-Activated Protein Kinase in Filamentous Fungi
... MAP kinase in the wild-type and os-1 mutant of ...putative histidine kinase, which was identical to the NIK1 gene product reported by Alex et ...the histidine kinase Os-1p, we ...
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Cellular transport of l histidine in Hartnup disease
... of histidine from blood were studied in two patients with Hartnup ...dietary histidine in the urine, whereas the fecal loss was ...plasma histidine and no increase in fecal histidine, ...
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The Structures of Biofilm-Controlling Proteins from Acinetobacter baumannii and Bacillus subtilis Reveal Details of DNA-binding Mechanisms and Illuminate Potential Therapeutic Targets
... In this model, SinI integrates into the helical hook of the C-terminal domain and drastically alters the tetrameric interface in two ways in addition to the displacement of a SinR monomer. First, the SinI α2 helix ...
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