type II collagen
Passive Transfer by Cells of Type II Collagen Induced Arthritis in Rats
... with type I collagen in ...solubilized type II collagen to unsensitized cells at the time of transfer or injection of heat-killed sensitized cells also did not cause arthritis in a ...
9
Humoral and Cellular Sensitivity to Collagen in Type II Collagen Induced Arthritis in Rats
... developed type-specific cellular as well as humoral ...was type II. The latter collagen induced brisk cellular and humoral responses that were equivalent whether complete Freund's adjuvant or ...
9
Nature and specificity of the immune response to collagen in type II collagen induced arthritis in mice
... native type II molecule although some reactivity with denatured collagen was ...denatured collagen primarily recognized covalent structural ...native type II collagen was ...
12
Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice
... towards type II collagen (CII) are detected in patients with rheumatoid arthritis (RA) and in non-human primates and rodents with collagen induced arthritis ...
10
Patella Alta and Trochlea Dysplasia Is Associated with Abnormal Type II Collagen and Matrix Accumulation in Chondrocytes
... in type II collagen, transmitted in an autosomal dominant manner from the mother to son and ...abnormal type II collagen heterofibrils and the putatively inherited dysplastic ...
11
Evidence for altered synthesis of type II collagen in patients with osteoarthritis
... with collagen fibrils (10). It represents a potential marker of type II procollagen synthe- sis in vivo as well as in ...of type II procollagen has been developed (11) and used to study ...
12
Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis
... to type II colla- gen (CII), an abundant molecule in articular cartilage, is implicated in pathogenesis because the immunization of susceptible strains of rats, mice and nonhuman primates using native CII ...
7
Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage
... of type II collagen in human articular cartilage in OA ...I, II, and III collagens can occur both in nonhelical sites (8) and through a triple helical ...helical collagen at neutral pH. ...
13
Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading
... of collagen type II, collagen type I and YKL40 expression, which persisted throughout the ...elevated collagen type II, collagen type I and YKL40 mRNA ...
10
Adoptive transfer of suppression of arthritis in the mouse model of collagen induced arthritis Evidence for a type II collagen specific suppressor T cell
... of collagen-induced ...native type II collagen 3 d before immunization with native type II collagen emulsified in complete Freund's adjuvant resulted in animals with ...
10
Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reaction
... five collagen genes (type I collagen, alpha 2 chain [COL1A2], type II collagen alpha 1 chain [COL2A1], type III collagen alpha 1 chain [COL3A1], type V ...
9
Sintered dicalcium pyrophosphate treatment attenuates estrogen deficiency-associated disc degeneration in ovariectomized rats
... Background: Estrogen deficiency is associated with musculoskeletal disorders. Sintered dicalcium pyrophosphate (SDCP) is a novel antiosteoporotic agent. In this study, we examined its use for restoration of bone quality ...
9
The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX II, is unique compared with other markers of collagen turnover
... other type II collagen degradation markers, such as Helix-II, which corresponds to a fragment originating from the helicoidal part of type II collagen ...different ...
12
Delayed union of femoral fractures in older rats:decreased gene expression
... tion (PCR, GeneAmp RNA PCR kit, N808-0143, Perkin Elmer, Foster City, CA), with primers (Table 1) designed for osteocalcin, type I collagen α 1, type II collagen, BMP- 2, BMP-4, ...
8
Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reaction
... five collagen genes (type I collagen, alpha 2 chain [COL1A2], type II collagen alpha 1 chain [COL2A1], type III collagen alpha 1 chain [COL3A1], type V ...
9
Hearing Loss in Patients with Spondyloepiphyseal Dysplasia Congenita and Tarda
... II collagen is associated with cartilage, however it is also found in other connective Ishibe and Yoo performed an extensive study of type II collagen within the temporal bone ...of ...
8
VDIPEN, a metalloproteinase generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis
... Abbreviations used in this paper: AC, articular cartilage; CII, type II collagen; CIA, type H collagen-induced arthritis; CLN, collagenase; ECM, extracellular matrix; GLN-A, gelatinase A[r] ...
10
Repair of a chondral defect using a cell free scaffold in a young patient - a case report of successful scaffold transformation and colonisation
... cell-free type I collagen matrix and reconstruction of the medial patellofemoral ligament, the patient was again treated arthroscopically for a tear of the medial meniscus of the same ...for type ...
7
Modulation of collagen induced arthritis by adenovirus mediated intra articular expression of modified collagen type II
... with type II collagen/complete Freund's adjuvant either three (square, triangle) or seven (circle, diamond) days after the injection and all mice were observed for the development of ...
9
The Effectiveness of Specific Collagen Peptides on Osteoarthritis in Dogs Impact on Metabolic Processes in Canine Chondrocytes
... (type II collagen, aggrecan and elastin), the RNA profile of inflammatory cy- tokines and degenerative matrix molecules was ...specific collagen peptides reduced catabolic processes, as ...
13