Type II membrane protein
Role of Pseudorabies Virus Us9, a Type II Membrane Protein, in Infection of Tissue Culture Cells and the Rat Nervous System
... The protein product of the pseudorabies virus (PRV) Us9 gene is a phosphorylated, type II membrane protein that is inserted into virion envelopes and accumulates in the trans-Golgi ...
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The Us9 Gene Product of Pseudorabies Virus, an Alphaherpesvirus, Is a Phosphorylated, Tail-Anchored Type II Membrane Protein
... chimeric protein was digested ...Us9 protein, and the only Us9 immunoreactive polypeptide was the Us9-EGFP fusion protein itself ...fusion protein during isolation and manipulation of the ...
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Golgi phosphoprotein 2 in physiology and in diseases
... kDa protein is coded by the gene GOLM1 located on human chromosome ...secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins using a ...
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Structural Determinants for Nuclear Envelope Localization and Function of Pseudorabies Virus pUL34
... nuclear membrane (INM) which is necessary for efficient nuclear ...a type II membrane protein of 262 amino acids ...functional protein despite continuing pUL31 binding, pointing ...
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Defective assembly and intracellular transport of mutant paramyxovirus hemagglutinin-neuraminidase proteins containing altered cytoplasmic domains.
... To determine whether the Nterminal cytoplasmic domain of a type II integral membrane protein plays a role in its intracellular assembly and transport, cDNA clones encoding mutant HN prot[r] ...
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Autographa californica Nucleopolyhedrovirus Ac76: a Dimeric Type II Integral Membrane Protein That Contains an Inner Nuclear Membrane-Sorting Motif
... plasma membrane of a cell allow the plasma membrane to be selectively permeabilized by low concentrations of digitonin, leaving the ER/nuclear envelope intact (8, ...chimeric protein containing the ...
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Molecular Basis of Cytotoxicity of Epstein-Barr Virus (EBV) Latent Membrane Protein 1 (LMP1) in EBV Latency III B Cells: LMP1 Induces Type II Ligand-Independent Autoactivation of CD95/Fas with Caspase 8-Mediated Apoptosis
... ing tBID) and its relocalization at the mitochondrial level, where tBID mediates opening of mitochondrial voltage-depen- dent anion channels, resulting in ⌬⌿ loss. Western blot results showed a marked decrease in ...
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Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen Occupied Vacuole via a Semipermeable Membrane
... vacuolar membrane is only semipermeable and is not grossly dam- aged or ...translocated protein appeared to increase from 8 to 10 h for ProA (see ...plasma membrane during phagocytosis and the LCV ...
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Immunostimulatory Activity of Major Membrane Protein II from Mycobacterium tuberculosis
... and M. tuberculosis (Rv1876) is only 90.6% at the amino acid level. Therefore, we assessed the immunostimulatory activity of M. tuberculosis-derived MMP and its fusion with BCG- derived HSP70 by using MMP-ML and ...
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The Complete Genome Sequence of J Virus Reveals a Unique Genome Structure in the Family Paramyxoviridae
... SH protein is poorly conserved between different paramyxoviruses and that the SH protein sequences of different MuV strains can differ from one another by as much as 23% ...are type II ...
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Review Article GP73 expression and its significance in the diagnosis of hepatocellular carcinoma: a review
... Golgi type II transmembrane protein, with a single, N-terminal transmembrane domain and an extensive, C-terminal coiled-coil domain located on the luminal surface of the Golgi apparatus ...Golgi ...
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Lang, Christina (2016): Transmembrane protein 106B, a risk factor in frontotemporal lobar degeneration, is a lysosomal type II transmembrane protein and affects autophagy. Dissertation, LMU München: Medizinische Fakultät
... lysosome-associated membrane protein 1 (LAMP1) and lysosome-associated membrane pro- tein 2 (LAMP2), two lysosomal marker proteins, increased concomitantly supporting a lysosomal involvement of GRN ...
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The Transmembrane Domain of the Respiratory Syncytial Virus F Protein Is an Orientation-Independent Apical Plasma Membrane Sorting Sequence
... cell membrane (29). The fusion (F) protein of RSV is a type I single-pass integral mem- brane protein embedded in the cell membrane of infected cells and in the viral envelope after ...
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Rho-Associated Coiled-Coil Kinase (ROCK) in Molecular Regulation of Angiogenesis
... monophosphate-activated protein kinase; Ang II: angiotensin II; AT1R: Ang II type 1 receptor; AT2R: Ang II type 2 receptor; CCM2: cerebral cavernous malformations 2; EC: ...
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Membrane binding of human immunodeficiency virus type 1 matrix protein in vivo supports a conformational myristyl switch mechanism.
... plasma membrane in a manner which is reversible upon phosphorylation of the mol- ecule (1, ...tate-mediated membrane binding which is regulated by the binding of GTP ...calcium-binding protein which ...
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Spinacia oleracea extract attenuates disease progression and sub chondral bone changes in monosodium iodoacetate induced osteoarthritis in rats
... Results: In vitro cell free and cell based assays indicated that SOE acts as a strong anti-oxidant and an anti- inflammatory agent. Histological analysis of knee joints at the end of the experiment by safranin-o and ...
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Localization of Human Immunodeficiency Virus Type 1 Gag and Env at the Plasma Membrane by Confocal Imaging
... represent membrane-dissociated protein produced during cell lysis or subcellular ...plasma membrane in HIV-1-infected cells (9), and with biochemical studies showing that the presence of membranes ...
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Inhibition of the Multiplication of Mycobacterium leprae by Vaccination with a Recombinant M. bovis BCG Strain That Secretes Major Membrane Protein II in Mice
... The BCG vaccine has been used for the prevention of tu- berculosis, although its role in the prevention of leprosy is still being debated. The protective efficacy of BCG against leprosy has been tested in several trials, ...
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Role of membrane environment and membrane spanning protein regions in assembly and function of the Class II Major Histocompatibility complex
... in Ii, likely through direct protein-protein interactions, between the -chain and ...of Ii and MHC-II molecules (either individually or as the preformed heterodimer) contribute to ...
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Spontaneous fusions to prv43 can suppress the export defect of pseudorabies virus gIII signal peptide mutants.
... Because the putative Prv43 protein is predicted to be a type III membrane protein containing six or more spanning domains, it appears that the export defect associated with the gIII sign[r] ...
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