Type IV Collagen
Alport familial nephritis Absence of 28 kilodalton non collagenous monomers of type IV collagen in glomerular basement membrane
... Immunochemical and biochemical analyses of the non-collagenous NC1 domain of type IV collagen isolated from the glomerular basement membranes GBM of three males with this disease demonst[r] ...
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Expression and immunohistochemical localization of laminin and type IV collagen in developing human fetal tracheal glands
... Int, J De\' BioI 37 491 495 (1993) 491 Short Contribution Expression and immunohistochemical localization of laminin and type IV collagen in developing human fetal tracheal glands AUDE V LALLEMAND, SA[.] ...
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Type IV collagen drives alveolar epithelial–endothelial association and the morphogenetic movements of septation
... that type IV collagen directs myofibroblast pro- liferation and migration, and the formation of septal-like formations in ...vitro. Type IV collagen appears to control the ...
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Production and Characterization of Recombinant Rat Non Collagen Domain of α3 Chain of Type IV Collagen α3 (IV) NC1 Antigen
... NC1 collagen domain. The type IV collagen inserted the plasmid pcBFT that encoded a BM40 protein secretion-signal peptide, a hexahistidine tag, sequence of enterokinase cleavage and ...
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The Increased Expressions of Type IV Collagen in Cochlear Fibroblasts of Diabetic Rat Models Caused by Curcumin Therapy
... of type IV collagen reported in our study is supported by previous study on DM that has found the ability of curcumin in inducing the transforming growth factor-β1 (TGF-β1) to stimulate the ...
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Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort
... distinct type IV col- lagen α -chains, namely α 1(IV) through α 6(IV), which are selectively expressed in different membranes at various stages of development and in specific tissues [5, ...of ...
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Benign familial hematuria due to mutation of the type IV collagen alpha4 gene
... the type IV collagen a4 chain is likely to be the pathogenic mutation in the BFH ...the type IV col- lagen a4 chain ...lagens, type IV collagen triple helices ...
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Molecular cloning of the human Goodpasture antigen demonstrates it to be the alpha 3 chain of type IV collagen
... polymerase chain reaction amplifications. The correspondence of the derived amino acid sequence of the new chain with published protein and cDNA sequences shows it to be the alpha 3 chain of type IV ...
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Identification of type IV collagen exposure as a molecular imaging target for early detection of thoracic aortic dissection
... Col-IV: type IV collagen; Col-I: type I collagen; Col-III: type III collagen; CDR: Col-IV-DOTA-Gd-rhodamine B; MRI: magnetic resonance imaging; NSE: ...
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Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen
... deposits. Type IV collagen was specifically identified as being modified by MDA adducts, using a variety of ...of type IV collagen was a site of adduct ...
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Lipocytes from normal rat liver release a neutral metalloproteinase that degrades basement membrane (type IV) collagen
... native type IV (basement membrane) collagen but not interstitial collagen types I or V and exhibits no activity against laminin or ...soluble collagen in vitro, it rapidly degrades ...
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Liver stiffness assessed by Fibrosis-4 index predicts mortality in patients with heart failure
... Concordant with these findings, in the present study, there were significant associations between type IV collagen 7S, PIIIP, hyaluronic acid, BNP and the FIB4 index. Moreover, right and left volume ...
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... [1]. Type IV collagen along with laminin, plays an important role in cell adhesion, migration, differentiation, and ...[2]. Type IV collagen, being the major component of ...
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“Urinary Collagen Type IV Levels in Type II Diabetic Nephropathy Syrian Patients” by Deemah Awwad, Adnan Al-Sabbagh, Faizeh Al-Quobaili, Syria.
... urinary type IV collagen excretion is increased in normoalbuminuric patients more than control group and it is increased with increased urinary albumin excretion, the same results were found in ...
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Tissue remodeling investigation in varicose veins
... strong type III collagen staining. Type III collagen was seen in the media of some varicose vein specimens (15%) but the staining was ...of type III collagen in both the ...
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Original Article Immunohistochemical expression of matrix metalloproteinase-9 and inhibitor of matrix metalloproteinase-1 in prostate adenocarcinoma
... the type IV collagen in the basement membrane of the prostatic glands was evaluated semi-quan- titatively in compliance with the following parameters 0-lack of collagen along the base- ment ...
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Changes in the expression of MMP2, MMP9, and ColIV in stromal cells in oral squamous tongue cell carcinoma: relationships and prognostic implications
... Methods: Here, we observed the changes in morphology and distribution of type IV collagen (ColIV) in the basement membrane (BM) surrounding nests of carcinoma in 48 patients with oral tongue squamous ...
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Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
... of type III collagen [17], C1M is from MMP-degraded type I collagen [25], C3M is from MMP-degraded type III collagen [26], C4M is from MMP-degraded type IV ...
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Isolation and characterisation of human epidermal stem cells
... Kératinocytes were harvested from neonatal foreskin. The cells adherent to type IV collagen within 5 minutes were isolated in 35mm tissue culture dishes (Nunc) as described below. Feeder cells were ...
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Maternal Nicotine Induces Collagen Type IV Changes in the Mice Lung Parenchyma and its Vessels
... Figure1. Microscopic comparison of the lung parenchyma of the experimental and control groups incubated with antibodies against collagen type IV. These figures indicate vascular sections (arrow ...
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