U87MG cells
Optical Imaging of Tumors with Copper-Labeled Rhodamine Derivatives by Targeting Mitochondria
... cultured U87MG glioma cells were pretreated with carbonylcyanide-m- chlorophenylhydrazone (CCCP) at 0, 50, 100 and 150 ...the U87MG glioma cells were washed with the phenol red-free Minimum ...
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Dendrosomal curcumin nanoformulation downregulates pluripotency genes via <em>miR-145</em> activation in U87MG glioblastoma cells
... of U87MG cells, a cellular model of glioblastoma, was evaluated by considering master genes of pluripotency and regulatory miRNA (microribonucleic ...suppresses U87MG cells growth with no ...
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The effects of ponatinib, a multi-targeted tyrosine kinase inhibitor, against human U87 malignant glioblastoma cells
... of U87MG cells, cell viability assay was performed after cells were treated with different concentrations of ponatinib for 72 ...on U87MG cells, we treated cells with 20 nM ...
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A novel diblock copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells
... cancer cells (Figure ...after cells were stained with ...mPEG-OA, U87MG cells were treated with concentrations close to the IC 50 (22 μ M) determined by the MTT ...for U87MG ...
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Modulation of MDR/MRP by wild type and mutant p53
... control cells from ...LN-308 cells but increased PGP expression in U87MG cells, (b) reduced MRP expression in four of the five (LN-18, U87MG, T98G, and LN-308) and MRP activity in two ...
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Inhibition of BMK1 pathway suppresses cancer stem cells through BNIP3 and BNIP3L
... stem cells. Proteins from A549, U87MG, iPS, ...A549 cells were serum starved overnight followed by treatment with/without 2 μmol/L XMD8-92 for 1 ...these cells were treated with EGF for 15 ...
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Role of miR-613 as a tumor suppressor in glioma cells by targeting SOX9
... (lacking the 3 ′ -UTR) and then subjected to a series of functional assays. Western blot analysis revealed that co-transfection with the SOX9 overexpression vector had successfully mitigated the miR-613 ...
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Cytotoxicity and apoptotic activities of alpha , gamma and delta tocotrienol isomers on human cancer cells
... evidences have revealed that each vitamin E isomer has its own pharmacodynamic profile [24,25]. The precise reason why certain isomers are more effective than the others as antitumor agents is still unclear; but undoubt- ...
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Human Immunodeficiency Virus-Restricted Replication in Astrocytes and the Ability of Gamma Interferon To Modulate This Restriction Are Regulated by a Downstream Effector of the Wnt Signaling Pathway
... untreated/non-cytokine-primed U87MG cells and primary ...49). U87MG cells and primary HFA were trans- fected with a TCF-4 dominant-negative mutant or GFP-encod- ing ...posttransfection, ...
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Polarized cell migration induces cancer type-specific CD133/ integrin/Src/Akt/GSK3 -catenin signaling required for mainte nance of cancer stem cell properties
... in cells expression each of four extracellular- and intracellular- domain CD133 deletion ...in U87MG cells but not NCI-N87 cells (Figure 7D and ...(in cells cultured on collagen- or ...
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Controlled release strategy of paclitaxel by conjugating to matrix metalloproteinases-2 sensitive peptide
... As known, MMP2 plays a critical role in tumour progression, tumour angiogenesis and metastasis; thus a cellular scratch assay was performed for investigating the metastasis inhibition of conjugate. In Figure 3, ...
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Different requirements for membrane fusion mediated by the envelopes of human immunodeficiency virus types 1 and 2.
... CD4independent fusion was not observed for the HIV-1 envelope or in cell lines permissive for CD4-dependent fusion mediated by the HIV-2 envelope, such as HeLa or U87MG cells 8, and prob[r] ...
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Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification
... with U87MG cells pre-incubated with αvβ3 standard ligand c(RGDyK). No fluorescence signal was observed indicating that c(RGDyK) occupied the receptors mediating the uptake of RWr and RWrNM. This suggested ...
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The histone demethylase JMJD2A promotes glioma cell growth via targeting Akt-mTOR signaling
... in U87MG glioma cells. U87MG cells were infected with lentivirus expressing sh-Ctrl or sh-JMJD2A for 48 ...in U87MG glioma cells. U87MG cells were infected with ...
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Suppression of miR-221 inhibits glioma cells proliferation and invasion via targeting SEMA3B
... level was detected using western blot. We found that although miR-221 inhibitor could upregulate the protein level of SEMA3B, and miR-221 mimic could downregulate expression of SEMA3B both in the NHA cells and in ...
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Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide
... the U87MG cell line to determine non-toxic levels of the LNCs to avoid cell ...the U87MG cells with the chitosan-transacylated LNCs/ anti-EGFR siRNA complex resulted in a reduction of EGFR expression ...
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CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1.
... HeLa cells and HeLa clones expressing different levels of CD4 were maintained in Dulbecco’s modified Eagle’s medium (DMEM) with 10% fetal bovine ...CV-1 cells and human astroglioma U87MG cells ...
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The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells
... glioma cells, but is involved in the pathophysiology of tumour-associated epilepsy ...both U87MG and U251MG glioma ...both U87MG and U251MG cells at a concentration of ≥ 30 μM pioglitazone (p ...
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Synergistic Apoptotic Effects of Tocotrienol Isomers and Acalypha wilkesiana on A549 and U87MG Cancer Cells
... towards U87MG cells with IC 50 values of ...9EA-treated U87MG cells with IC 50 value below the 20 µg/ml potency level for plant extract as established by the national cancer institute (NCI) ...
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NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells
... the U87MG cell line, displayed higher NRF2 mRNA ...between cells lines and TMZ-induction of NRF2 were confirmed for protein expression, by western blot ...U138MG cells in comparison to U87MG ...
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