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unaffected relatives

Review Article Altered gray matter and brain activity in patients with schizophrenia and their unaffected relatives: a multimodal meta-analysis of voxel-based structural MRI and resting-state fMRI studies

Review Article Altered gray matter and brain activity in patients with schizophrenia and their unaffected relatives: a multimodal meta-analysis of voxel-based structural MRI and resting-state fMRI studies

... their unaffected relatives might be excellent clinical features for examining the association between neurodevelopmental abnor- malities and genetic and environmental risk ...their unaffected ...

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Abnormal Frontoparietal Synaptic Gain Mediating the P300 in Patients with Psychotic Disorder and Their Unaffected Relatives

Abnormal Frontoparietal Synaptic Gain Mediating the P300 in Patients with Psychotic Disorder and Their Unaffected Relatives

... in unaffected relatives at frontal and parietal ...Additionally, relatives show a loss of the normally increased self-inhibition in frontal and parietal areas during target ...in relatives ...

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Abnormalities of localized connectivity in schizophrenia patients and their unaffected relatives: a meta-analysis of  resting-state functional magnetic resonance imaging studies

Abnormalities of localized connectivity in schizophrenia patients and their unaffected relatives: a meta-analysis of resting-state functional magnetic resonance imaging studies

... no consistent region was found to be changed compared with controls, indicating that abnormal localized functional connectivity may be widely and uniquely distributed in schizophrenia patients and their unaffected ...

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Islet cell antibodies predict insulin dependent diabetes in United States school age children as powerfully as in unaffected relatives

Islet cell antibodies predict insulin dependent diabetes in United States school age children as powerfully as in unaffected relatives

... dependent diabetes (IDD) are predictive of the disease, a finding that permits the design of intervention strategies to prevent it. However, 85% or more of patients with new onset IDD have no affected relative. We ...

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Familial testicular germ cell tumor: no associated syndromic pattern identified

Familial testicular germ cell tumor: no associated syndromic pattern identified

... their unaffected relatives, but these differences were not statistically ...clinically unaffected relatives displaying one or more of these traits are unidentified carriers of a familial TGCT ...

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Impaired Prefrontal Synaptic Gain in People with Psychosis and Their Relatives during the Mismatch Negativity

Impaired Prefrontal Synaptic Gain in People with Psychosis and Their Relatives during the Mismatch Negativity

... Our results also suggest that patients show a further increase in excitability in rIFG across task conditions com- pared to unaffected relatives. This may indicate that—at least in prefrontal cortex—there ...

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Temporal discrimination threshold: VBM evidence for an endophenotype in adult onset primary torsion dystonia

Temporal discrimination threshold: VBM evidence for an endophenotype in adult onset primary torsion dystonia

... five unaffected relatives with abnormal TDTs (II:2, II:4, III:6, III:7, III:17) are identified along with six unaffected relatives with normal TDTs who may be included in a genetic ...an ...

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Antioxidant defense system and family environment in adolescents with family history of psychosis

Antioxidant defense system and family environment in adolescents with family history of psychosis

... cost, such as immune function, antioxidant defence and DNA repair processes [14]. The relationship between en- vironmental conditions and oxidative stress has not been examined in healthy humans. In a previous study, we ...

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Colorectal cancer and self-reported tooth agenesis

Colorectal cancer and self-reported tooth agenesis

... The reported association between AXIN2 variants, colorectal cancer, and tooth agenesis suggests that these conditions may be associated. However, no large-scale studies of colorectal cancer (CRC) patients have been ...

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Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms?

Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms?

... found using high angular resolution diffusion imaging (HARDI) with 61 diffusion directions that neuron tracts between frontal cortices and limbic as well as temporal and parietal brain regions are characterized by better ...

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Temporal discrimination thresholds as an endophenotype in adult onset primary torsion dystonia

Temporal discrimination thresholds as an endophenotype in adult onset primary torsion dystonia

... What is the frequency of abnormal temporal discrimination thresholds amongst clinically unaffected relatives of both sporadic and familial adult onset primary torsion dystonia patients..[r] ...

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Temporal discrimination: Mechanisms and relevance to adult onset dystonia

Temporal discrimination: Mechanisms and relevance to adult onset dystonia

... Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired ...

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Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives

Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives

... their unaffected first‑degree relatives and healthy individuals As depicted in ...their unaffected first-degree relatives and ...their unaffected relatives (B = ...between ...

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Optimal Weights in Nonparametric Analysis of Clustered ROC Curve Data

Optimal Weights in Nonparametric Analysis of Clustered ROC Curve Data

... within-cluster unaffected-affected units correlation and the proportion of clusters that contain both unaffected and affected units is small, using either of the two weighting schemes, corresponding to ...

6

Motor imagery of the unaffected hand in children with spastic hemiplegia

Motor imagery of the unaffected hand in children with spastic hemiplegia

... Participants were presented with five individual sheets of laminated paper. Each sheet had an 80mm vertical line, as well as a target box with its closest edge 30mm from the vertical line (see Figure 1). The width of the ...

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Impact of Cystic Fibrosis on Unaffected Siblings: A Systematic Review

Impact of Cystic Fibrosis on Unaffected Siblings: A Systematic Review

... suggested that unaffected siblings lacked understanding of CF, this was expressed as “battling the unknown”. Mothers of children with CF reported feeling responsible for answering difficult questions about ...

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Community differentiation of the cutaneous microbiota in psoriasis

Community differentiation of the cutaneous microbiota in psoriasis

... the unaffected, and control specimens (Figure ...from unaffected sites of psoriasis patients, and that each lesion harbors a more distinct community of microbes compared to other ...and unaffected ...

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Trend of Stock Market and Its Impact on Indian Economy

Trend of Stock Market and Its Impact on Indian Economy

... Most people, who do not own shares, will be largely unaffected by short term movements in the stock market. However, ordinary workers are not completely unaffected by the st[r] ...

8

In Defense of Our Relatives

In Defense of Our Relatives

... to the wounded and ill. Occupying the camp was physically difficult. This was particularly true as the days got shorter, the wind grew stronger, the temperature dropped and violence increased. There was not a lot of ...

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PPP1R15A mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz

PPP1R15A mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz

... We quantified the dependence of eIF2a-P dephosphorylation rates on both the concentration of the regulatory human PPP1R15A subunit EC50 = 7 nM and on the ancillary G-actin subunit EC50 =[r] ...

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