urothelial carcinoma
Targeting Hsp90 in urothelial carcinoma
... metastatic urothelial carcinomas. Growth factor signaling is increased in urothelial carcinoma ...in urothelial carcinomas ...some urothelial carcinomas, allowing for uninhibited Ras ...
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Isolated cardiac metastasis from plasmacytoid urothelial carcinoma of the bladder
... A review of hematoxylin and eosin (H&E) stained sec- tions of the biopsied primary tumor demonstrated an invasive urothelial carcinoma with discohesive epithelial cells and plasmacytoid features (Figure ...
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Plasmacytoid urothelial carcinoma (PUC): Imaging features with histopathological correlation
... Fig. 4. 65-year-old male with plasmacytoid urothelial carcinoma (PUC) who underwent staging magnetic resonance imaging. Rectal examination at time of cystoscopy demonstrated pinpoint narrowing of the ...
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High-grade urothelial carcinoma with squamous differentiation metastasizing to the tongue.
... of urothelial carcinoma to the maxillofacial region is exceedingly rare and mostly involves the ...of urothelial carcinoma metastasizing to the ...
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Integrative analysis of the epigenetic basis of muscle-invasive urothelial carcinoma
... Epigenetic changes and modifications are an important part of carcinogenesis and subsequent tumor progres- sion [24, 25]. Of the various epigenetic mechanisms, DNA methylation has been most studied and is classic- ally ...
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Case Report Transition between urothelial carcinoma in situ and non-invasive micropapillary carcinoma as a pivot connection between diverse morphologies of bladder carcinoma: a case report of urothelial carcinoma with villoglandular differentiation
... papillary urothelial car- cinoma (5%), urothelial carcinoma with villo- glandular differentiation (15%), non-invasive micropapillary carcinoma (25%), urothelial car- cinoma in situ ...
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New therapeutic targets in the management of urothelial carcinoma of the bladder
... Abstract: Urothelial carcinoma of the bladder, despite the myriad of treatment approaches and our progressively increasing knowledge into its disease processes, remains one of the most clinically ...
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Urothelial carcinoma: the evolving landscape of immunotherapy for patients with advanced disease
... In this study, two different cohorts of sequential therapy were evaluated for patients with metastatic urothelial carcinoma, with 28 patients included in total. Cohort A consisted of 14 chemotherapy naïve ...
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MCM10 overexpression implicates adverse prognosis in urothelial carcinoma
... to inhibit growth of human colon adenocarcinoma HT29 cells in vitro [35]. Mechanistically, anti-MCM small molecules are most likely to stop the proliferation of cancer cells by blocking replication licensing or ...
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Preliminary evaluation of urinary soluble Met as a Biomarker for urothelial carcinoma of the bladder
... aggressive urothelial tumors [24]; in a limited survey of human urothelial cancer-derived cell lines, we found that Met content correlated directly with disease grade and metastatic potential in mice ...
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Identification of key pathways and genes influencing prognosis in bladder urothelial carcinoma
... RNA urothelial carcinoma associated 1-regulated cell cycle via CREB protein and the PI3K-AKT- dependent pathway in bladder cancer, wherein CREB plays a tumor suppressor role in ...
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Canadian guidelines for postoperative surveillance of upper urinary tract urothelial carcinoma
... 27. Wu CF, Pang ST, Chen CS, et al. The impact factors on prognosis of patients with pT3 upper urinary tract transitional cell carcinoma. J Urol 2007;178:446-50. http://dx.doi.org/10.1016/j.juro.2007.03.115 28. ...
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Trends and disparities in the use of neoadjuvant chemotherapy for muscle invasive urothelial carcinoma
... Introduction: Neoadjuvant chemotherapy (NAC) prior to radical or partial cystectomy is considered the standard of care for eli- gible patients with muscle-invasive urothelial carcinoma. Despite guideline ...
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Trends and disparities in the use of neoadjuvant chemotherapy for muscle invasive urothelial carcinoma
... Introduction: Neoadjuvant chemotherapy (NAC) prior to radical or partial cystectomy is considered the standard of care for eligible patients with muscle-invasive urothelial carcinoma. Despite guideline ...
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Original Article MicroRNA200c suppresses urothelial carcinoma invasiveness by targeting FSCN1
... Abstract: The tumor suppressor miR200c, a metastasis-suppressing miRNA important in epithelial-to-mesenchymal transition (EMT), is down-regulated in many tumor types, including urothelial carcinoma (UC). ...
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Recurrence pattern and TP53 mutation in upper urinary tract urothelial carcinoma
... TP53 mutation patterns are associated with prognosis of various cancers. This study was designed to investigate the association between TP53 mutation patterns and recurrence patterns in upper urinary tract ...
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Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems
... In-silico ChIP-Seq analysis of the promoters revealed a strong enrichment for PPARG binding (40 % bound, p < 10 −6 ), in line with PPARG involvement in lipid metabol- ism [25]. Unsupervised quality threshold ...
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Original Article Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms’ tumor
... cell carcinoma (RCC) is a tumor that recapitulates the phenotypic features of mature renal ...Papillary urothelial carcinoma (PUC) phenotypically recapitulate features of mature urotheliuim [23] and ...
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Critical evaluation of vinflunine in the treatment of refractory metastatic urothelial carcinoma
... Abstract: Urothelial carcinoma (UC) accounts for 5% to 10% of malignancies in men in Europe and the United States. For locally advanced or metastatic disease, there are two standard first- line chemotherapy ...
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Emerging biomarkers for the diagnosis and monitoring of urothelial carcinoma
... tract urothelial carcinoma treated in the last two decades: a retrospective analysis based on a mul- ticenter collaborative ...Tract Urothelial Carcinoma Collaboration ...tract ...
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