Uukuniemi virus
Reverse Genetics System for Uukuniemi Virus (Bunyaviridae): RNA Polymerase I-Catalyzed Expression of Chimeric Viral RNAs
... phlebovirus Uukuniemi virus, a member of the Bunyaviridae family, by using RNA polymerase I (pol I)-mediated ...the Uukuniemi virus sense or complementary RNA derived from the medium-sized (M) ...
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Immunocytochemical analysis of Uukuniemi virus budding compartments: role of the intermediate compartment and the Golgi stack in virus maturation.
... a virus have to reach a critical concentration in the budding ...of Uukuniemi virus the concentra- tion of properly folded glycoproteins in the ER may be too low to promote virus ...Toro ...
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Characterization of the Uukuniemi Virus Group (Phlebovirus: Bunyaviridae): Evidence for Seven Distinct Species
... the Uukuniemi virus group be assigned to five different species as follows: Uukuniemi virus, EgAn 1825-61 virus, Fin V707 virus, Chizé virus, and Zaliv Terpenia ...
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Targeting of a Short Peptide Derived from the Cytoplasmic Tail of the G1 Membrane Glycoprotein of Uukuniemi Virus (Bunyaviridae) to the Golgi Complex
... Our present and previous (2) results do not support a role for the TMD in retaining G1 of Uukuniemi virus in the Golgi complex. Central to this conclusion is the question of how the TMD of G1 is defined. A ...
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Generation and Analysis of Infectious Virus-Like Particles of Uukuniemi Virus (Bunyaviridae): a Useful System for Studying Bunyaviral Packaging and Budding
... Hantaan virus requires coexpression of both the N protein and the viral gly- coproteins ...vaccinia virus) were used, and VLPs were observed in the supernatant in the vaccinia virus ...Vaccinia ...
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Mutational Analysis of the Uukuniemi Virus (Bunyaviridae Family) Promoter Reveals Two Elements of Functional Importance
... phlebovirus Uukuniemi (UUK), a member of the Bunyaviridae ...UUK virus-sense RNA (vRNA) derived from the medium-sized (M) RNA ...UUK virus helper ...
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Functional Analysis of the Noncoding Regions of the Uukuniemi Virus (Bunyaviridae) RNA Segments
... UUK virus minigenomes did not follow the same kinetics. All UUK virus minigenomes showed a strong increase of reporter gene activity between 10 and 22 h post- ...BUN virus (Orthobunyavirus ...
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Processing and membrane topology of the spike proteins G1 and G2 of Uukuniemi virus.
... The membrane glycoproteins G1 and G2 of the members of the Bunyaviridae family are synthesized as a precursor from a single open reading frame. Here, we have analyzed the processing and membrane insertion of G1 and G2 of ...
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Uukuniemi Phlebovirus Assembly and Secretion Leave a Functional Imprint on the Virion Glycome
... Uukuniemi virus (UUKV) was first isolated in 1960 from ticks in southeast Finland (16) and has been adopted as a prototype for studying phlebovirus ultrastructure (17, 18) and pathobiology ...
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The Glycoprotein Cytoplasmic Tail of Uukuniemi Virus (Bunyaviridae) Interacts with Ribonucleoproteins and Is Critical for Genome Packaging
... of virus particles, as shown, e.g., for Semliki Forest virus (40), simian virus 5 (38), murine leukemia virus (27), and Ebola virus ...of virus particles, as demonstrated, ...
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The Cytoplasmic Tails of Uukuniemi Virus (Bunyaviridae) GN and GC Glycoproteins Are Important for Intracellular Targeting and the Budding of Virus-Like Particles
... UUK virus (30), a member of the Phlebovirus genus, one of five genera in the Bunyaviridae family, and a model virus for this family of viruses ...UUK virus (30) and are therefore a useful system for ...
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Uukuniemi Virus as a Tick-Borne Virus Model
... of virus stocks produced in mammalian ...including Uukuniemi virus (UUKV), a phlebovirus originally isolated from the tick Ixodes ricinus in the 1960s ...late-penetrating virus, belonging to a ...
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Discovery and Evolution of Bunyavirids in Arctic Phantom Midges and Ancient Bunyavirid-Like Sequences in Insect Genomes
... phantom virus (NOMV), and four phleboviruses (Jacunda virus [JANV] [included because this is the closest BLASTp match to KIGV Gn-Gc], sandfly fever Naples virus [SFNV], Rift Valley fever virus ...
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Characterization of the Golgi Retention Motif of Rift Valley Fever Virus GN Glycoprotein
... RVF virus glycoproteins, either model could be employed to explain our ...RVF virus oli- gomerize (unpublished ...RVF virus glycoproteins, experiments are under way to address this ...
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The Cytoplasmic Tail of Infectious Bronchitis Virus E Protein Directs Golgi Targeting
... We have previously shown that the E protein of the coronavirus infectious bronchitis virus (IBV) is localized to the Golgi complex when expressed exogenously from cDNA. Here, we report that neither the ...
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Isolation, Genetic Characterization, and Seroprevalence of Adana Virus, a Novel Phlebovirus Belonging to the Salehabad Virus Complex, in Turkey
... Sand fly trapping. Sand fly trapping campaigns were conducted from August 2012 to September 2012 in Adana (Mediterranean region, Turkey) using CDC miniature light traps as previously reported (29). Live sand flies were ...
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Mutational Analyses of the Nonconserved Sequences in the Bunyamwera Orthobunyavirus S Segment Untranslated Regions
... recombinant virus followed the same pattern as S mRNA lev- els, indicating that effects on N protein synthesis were likely the direct result of effects on ...
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