vaccine development
Recent advances in canine leptospirosis: focus on vaccine development
... As long as no novel efficacious and broadly protecting leptospirosis vaccines have been developed, multivalent bac- terins such as the tetravalent vaccines in the US and Europe will aid in the battle against canine ...
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Adenoviral Vectors in Veterinary Vaccine Development: Potential for Further Development
... the vaccine candidate in animal models and field ...veterinary vaccine would involve obtaining permission from veterinary au- thorities to allow the vaccine to be made available to the relevant ...
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Adjuvants in malaria vaccine development strategies: a review
... malarial antigens or co-expressed on a separate vector and co-injected with the vaccine [49] . This method provides adjuvant activity at the site of antigen production with long-lasting effect from transfected ...
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Advances and challenges in malaria vaccine development
... malaria vaccine would be a valuable tool to reduce the disease burden and could contribute to elimination of malaria in some regions of the ...malaria vaccine candidates are directed against human and ...
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ILEOSTOMY CARE IN TYPHOID PERFORATION PERITONITIS AND VACCINE DEVELOPMENT
... The present study "Ileostomy care in typhoid perforation peritonitis and vaccine development was carried out in Department of Environmental Biology A.P.S University Rewa (M.P). The diagnosis of typhoid ...
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Hepatitis C Virus and Vaccine Development
... experience (6). However, toxicity is very important in any experimental therapeutic agent (7). The chronic stage of infection is mainly related to HCV pathogenicity, hence there is a need to improve the ability of a ...
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Targeting and exploiting cytomegalovirus for vaccine development
... the vaccine development ...of vaccine efficacy, which will apply to many infections and not be limited to chronic ...designing vaccine vectors or synthetic ...
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Systems vaccinology and big data in the vaccine development chain
... monitor vaccine safety and efficacy in larger popula- tions ...the vaccine life cycle, cor- relates of protection, or surrogates thereof, are sometimes known, however the mechanism of action is often under- ...
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<p>Immunoinformatics and Vaccine Development: An Overview</p>
... potential vaccine design advance, immune-related concerns (as seen with speci fi c vulnerable populations, cases of emerging/re- emerging infectious disease, pathogens with complex lifecycle and antigenic ...
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Nanoparticles in Vaccine Development
... Since the invention and introduction of vaccines by Edward Jenner in 1796 [1], vaccination has had a significant role in societies public health. Some diseases that were nightmares for human one day and used to cause ...
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Phage display as a promising approach for vaccine development
... as vaccine delivery ...optimal vaccine delivery systems is their imunostimulatory characteristics and potent adjuvant ...enables vaccine researchers to find potential mimotopes with high antigenicity ...
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Bacterial infectious disease control by vaccine development
... Shigella vaccine that is sufficiently attenuated to be nonreactogenic yet ade- quately invasive to be highly immunogenic has been attempted for over 30 ...most vaccine development work has been with ...
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Unique Model of Dormant Infection for Tuberculosis Vaccine Development
... In vitro growth and survival of M. tuberculosis strain 18b. Unique strain 18b was isolated in 1955 by Hashimoto (10) from a patient with pulmonary tuberculosis caused by a streptomy- cin-“resistant” strain of M. ...
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Immune Responses and Vaccine Development for Cytomegalovirus Infections
... attenuated vaccine strain of canary pox virus, which replicates productively in avian species but abortively in mammalian ...the development of these vectors for various vaccine applications ...gB ...
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Prime boost strategies for malaria vaccine development
... the development of DNA vaccines has been the emergence of recombinant viral vectors, such as poxviruses and adenoviruses, as vaccine delivery ...smallpox vaccine in 120·000 people in the 1970s, ...
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The Importance of Animal Models in Tuberculosis Vaccine Development
... TB vaccine research and development tend to be multicentred and use challenge models with ...the vaccine candidate has intrinsic complexities due to the slow growth of the microorganism, the length ...
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Targeting antigens to dendritic cell receptors for vaccine development
... Furthermore, both oxidized and reduced mannan stimulated bone marrow derived DCs, showed enhanced allogeneic T- cell proliferation, and enhanced OTI/OTII peptide specific T-cell responses in vitro. Mice injected with ...
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Update on vaccine development for renal cell cancer
... We have come far in the past decade in developing a better understanding of how the immune system recognizes RCC and how the optimal function of protective anti-RCC T-cell-mediated immunity may be altered in chronic dis- ...
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Perspectives for therapeutic HPV vaccine development
... DNA vaccine on CIN 2/3 lesions in a randomized, double- blind, placebo-controlled study ...new vaccine formulation INO-3112, incorp- orating the proprietary immune activator expressing IL- 12 (INO-9012) ...
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A Single-Dose Influenza A (H5N1) Vaccine Safe and Immunogenic in Adult and Elderly Patients: an Approach to Pandemic Vaccine Development
... H5N1 vaccine in adult and elderly ...the vaccine or one dose of 6 or 12 ...present vaccine is safe and immunogenic in healthy adult and elderly subjects and requires low doses and, unlike any other ...
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