Vaccinia viruses
Expression of functional Bunyamwera virus L protein by recombinant vaccinia viruses.
... The N protein was detected in cells expressing L protein from vaccinia viruses and transfected with Bunyamwera virus nucleocapsids lanes 2 and 3 but not in cells infected with vTF7-3 alo[r] ...
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Vaccination with recombinant vaccinia viruses expressing ICP27 induces protective immunity against herpes simplex virus through CD4+ Th1+ T cells.
... This study was designed to evaluate the efficacy and mechanisms of protection mediated by recombinant vaccinia viruses encoding immediate-early (IE) proteins of herpes simplex virus type 2 (HSV-2). Three ...
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Control of Viremia and Prevention of Simian-Human Immunodeficiency Virus-Induced Disease in Rhesus Macaques Immunized with Recombinant Vaccinia Viruses plus Inactivated Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 1 Particles
... rhesus macaque animal model system (26, 37) to evaluate a vaccine regimen, which presents the HIV-1 envelope in its most native form, i.e., as a component of intact virions. Aldri- thiol-2 (AT-2)-inactivated particles ...
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Characterization of Hepatitis E Virus Recombinant ORF2 Proteins Expressed by Vaccinia Viruses
... study, vaccinia viruses have been used to express recombinant HEV ORF2 proteins, allowing the study of their glycosylation patterns and subcellular ...
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Genome Scale Patterns of Recombination between Coinfecting Vaccinia Viruses
... SFV-reactivated vaccinia viruses. A third small collection of recombinant viruses was also produced using Shope fibroma virus-mediated DNA reactivation assays and DNAs extracted from DPP17 and ...
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Rift Valley fever virus M segment: use of recombinant vaccinia viruses to study Phlebovirus gene expression.
... By manipulation of RVFV sequences present in the recombinant vaccinia viruses and use of specific antibody reagents, it was found that the 78-kDa protein initiated at the first initiatio[r] ...
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Protection of mice from respiratory Sendai virus infections by recombinant vaccinia viruses.
... recombinant vaccinia viruses and that replication of the vaccinia virus in the respiratory mucosal layer is required for induction of the efficient mucosal immunity, which is accomplished only by ...
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Response of dairy calves to vaccinia viruses that express foreign genes
... Repeated intradermal inoculations of calves with wild-type vaccinia virus and recombinant vaccinia viruses expressing human hepatitis B virus surface antigen and herpes simplex virus, ty[r] ...
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Myxoma and Vaccinia Viruses Bind Differentially to Human Leukocytes
... attachment vaccinia vi- rion proteins have also been identified to date, including A26, A27, D8, H3, and L1 (24–28, ...of vaccinia virus IMV with soluble heparin or laminin had an inhibitory effect on the ...
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Pathogeneses of respiratory infections with virulent and attenuated vaccinia viruses
... piratory viruses, such as influenza and SARS viruses, rap- idly replicate in the lung after intranasal infection and the virus titers reached a peak at 1–2 days post-infection [32- ...various viruses ...
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Isolation and characterization of cidofovir resistant vaccinia viruses
... confers cross protection to other orthopoxviruses includ- ing those that infect humans, e.g. monkeypox and cowpox viruses. Although cidofovir (CDV) has been approved under an investigational new drug application ...
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The membrane-associated and secreted forms of the respiratory syncytial virus attachment glycoprotein G are synthesized from alternative initiation codons.
... Analysis of the proteins synthesized from these cDNAs, either by translation of transcripts in a cell-free system or in cells infected with recombinant vaccinia viruses containing either[r] ...
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Polyvalent Envelope Glycoprotein Vaccine Elicits a Broader Neutralizing Antibody Response but Is Unable To Provide Sterilizing Protection against Heterologous Simian/Human Immunodeficiency Virus Infection in Pigtailed Macaques
... second vaccinia virus immunization in the other vaccine ...second vaccinia virus im- munization and reached titers over 1:100,000 following the first protein ...recombinant vaccinia viruses in ...
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Human immunodeficiency virus-like, nonreplicating, gag-env particles assemble in a recombinant vaccinia virus expression system.
... DISCUSSION We have shown in this study that coexpression of the HIV-1 core and envelope proteins in mammalian cells infected with recombinant vaccinia viruses resulted in the assembly an[r] ...
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T-cell responses to highly conserved CD4 and CD8 epitopes on the outer membrane protein of bovine leukemia virus: relevance to vaccine development.
... Protection of sheep against bovine leukemia virus BLV infection by vaccination with recombinant vaccinia viruses expressing BLV envelope glycoproteins: correlation of protection with CD4[r] ...
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Identification of gp120 Regions Targeted by a Highly Potent Neutralizing Antiserum Elicited in a Chimpanzee Inoculated with a Primary Human Immunodeficiency Virus Type 1 Isolate
... a control experiment for this and other gp120 immunoprecipi- tations, the direct analysis of the two parental and nine chi- meric gp120s produced in HeLa cells following infection with recombinant vaccinia ...
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Comprehensive Screening for Human Immunodeficiency Virus Type 1 Subtype-Specific CD8 Cytotoxic T Lymphocytes and Definition of Degenerate Epitopes Restricted by HLA-A0207 and -CW0304 Alleles
... recombinant vaccinia viruses expressing the HIV-1 gag, env, and nef gene products from the principal subtypes of the virus representing the global pandemic and an Elispot format assay allow rapid ...
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Identification of a Dynein Interacting Domain in the Papillomavirus Minor Capsid Protein L2
... The L2 protein contains at least two nuclear localization signals (NLSs) and an additional signal for association with PML bodies (2). Nuclear translocation of L2 synthesized in the cytoplasm is rapid and requires the ...
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Role of conserved glycosylation sites in maturation and transport of influenza A virus hemagglutinin.
... Expression of the altered HA proteins in eukaryotic cells by a panel of recombinant vaccinia viruses revealed that rates and efficiency of intracellular transport of HA are dependent upo[r] ...
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Structure and genetic variability of envelope glycoproteins of two antigenic variants of caprine arthritis-encephalitis lentivirus.
... Immunoprecipitation of native CAEV antigens with sera from goats immunized with recombinant vaccinia viruses demonstrated that antibody responses induced by the recombinant products enco[r] ...
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