Vaginal mucosa
Transcriptional fingerprints of antigen-presenting cell subsets in the human vaginal mucosa and skin reflect tissue-specific immune microenvironments
... We generated a transcriptional dataset of 87 microarray samples spanning eight APC populations across human va- gina, skin and blood. Complementary transcript and network-level analyses of these data, combined with in ...
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Direct application of plasmid DNA containing type I interferon transgenes to vaginal mucosa inhibits HSV-2 mediated mortality
... In ICR mice, which are highly susceptible to the lethal effects of herpes (35), we previously showed that transfection of mouse corneas with IFN-α1 and –β transgenes, 24 hours prior to HSV-1 infection, enhanced the ...
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Expression of Type III Interferon (IFN) in the Vaginal Mucosa Is Mediated Primarily by Dendritic Cells and Displays Stronger Dependence on NF-κB than Type I IFNs
... Inhibition of the NF- B pathway abrogates expression of type III but not type I IFN in vitro and in vivo. The differential induction of type III IFN by TLR and RLR agonists correlated with activation of NF- B. We ...
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Transcriptomic Analysis of Streptococcus pyogenes Colonizing the Vaginal Mucosa Identifies hupY, an MtsR Regulated Adhesin Involved in Heme Utilization
... the vaginal tract and because of its observed properties as an adhesin, we tested the ability of GAS and GBS ΔhupY mutants to colonize the murine vaginal ...for vaginal colonization, some questions ...
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Tolerability and hydrating effects of an anti aging gynaecological collagen cream in women in menopause
... comfort. Vaginal, perineal and abdominal tolerability of the cream was excellent at both assessment time points according to both dermatologist’s and gynaecologist’s ...evaluation. Vaginal, perineal and ...
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Resistance to Infection, Early and Persistent Suppression of Simian Immunodeficiency Virus SIVmac251 Viremia, and Significant Reduction of Tissue Viral Burden after Mucosal Vaccination in Female Rhesus Macaques
... and vaginal mucosa of the intestinally vaccinated animals than in the other groups (P ⫽ ...rectal mucosa of orally vaccinated animals (P ⫽ 0.01) and in the vaginal mucosa of nasally ...
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Diagnostic test of urine sample, vaginal smear and combination of urine with vaginal smear to identify Neisseria gonorrhoeae with polymerase chain reaction method
... of vaginal smear in our study showed lower results. From this result vaginal smear has a low sensitivity and moderate specificity so that vaginal smears cannot be used as a sample for identifying ...
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Vaginal Memory T Cells Induced by Intranasal Vaccination Are Critical for Protective T Cell Recruitment and Prevention of Genital HSV-2 Disease
... the vaginal epithelium before spreading to the central nervous system and establishing lifelong latency ...the vaginal mucosa are critical gatekeepers for rapid clear- ance of the invading HSV-2 at ...
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NK and NKT Cell-Independent Contribution of Interleukin-15 to Innate Protection against Mucosal Viral Infection
... Innate immunity plays a crucial role in the defense against viral infections (6, 7). This is especially true for mucosal sur- faces, where the vast majority of pathogens initiate infection (18). Indeed, as we and others ...
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Vaginal partitioning with vertical septum—an alternative to colpocleisis
... For the formation of the septum, continuous vertical mattress stitches are taken starting from the apical point (point e in Fig. 8). One end of the suture is used to make stitches on the right side while the other end is ...
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Anal gland adenocarcinoma in situ with pagetoid spread: a case report
... Case presentation: Physical examination in a 75-year-old woman revealed an erythematous, inflamed, perianal skin lesion. Neither colposcopy, cystoscopy, colonoscopy, computed tomography, nor magnetic resonance imaging ...
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Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infection
... the mucosa via the epithelial CD4 ⫹ T cells through CD4 and CCR5 and replicated in these cells ...noninflamed vaginal mucosa, and these lymphocytes were always located in the basal region of the ...
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Replication characteristics of equine herpesvirus 1 and equine herpesvirus 3: comparative analysis using ex vivo tissue cultures
... activated in the vaginal mucosa. EHV-1 infection induces high antiviral interferon-α levels, which is critical in the host innate immune response [32]. Another possible explanation for the difference in ...
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Impedance pattern of vaginal and vestibular mucosa in cyclic goats
... of vaginal mucosa in farm animals has been a two-terminal technique (McCaughey and Patterson, 1981; Ko et ...the vaginal im pe- dan ce by four-terminal ...
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Vaginal Myeloid Dendritic Cells Transmit Founder HIV-1
... and vaginal T cells ...explanted vaginal tissue was taken up by vaginal DCs and transported through the mucosa and trans infected sys- temic and mucosal mononuclear target ...each ...
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The Outpatient Burch Sling Procedure: A Nerve Sparing Method for Correcting Female Urinary Incontinence
... anterior vaginal walls pre- serves the nerves while correcting urinary ...the vaginal nerve from the autonomic nerve division ...the vaginal mucosa and endopelvic ...
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The Quantity of Latent Viral DNA Correlates with the Relative Rates at Which Herpes Simplex Virus Types 1 and 2 Cause Recurrent Genital Herpes Outbreaks
... characteristic appearance of acute disease and the titers of daily vaginal swabs were determined on Vero cell monolayers. Animals infected with HSV-1 developed somewhat milder lo- cal and systemic disease (data ...
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Wirth, Monika (2007): Immunology of the genital tract - a review. Dissertation, LMU München: Medizinische Fakultät
... at vaginal level are totally uncoupled to those occurring at the periphery (310), suggesting either an immunological independence, or compartmentalization of the vaginal mucosa, or a differential ...
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PubMedCentral-PMC5145791.pdf
... against vaginal hygiene ...to vaginal hygiene practices: (i) vaginal hygiene practices, especially those affecting lubrication of vaginal mucosa, could put the individual at increased ...
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Menopausal Problems Among Rural and Urban Women From Eastern India
... The study confirmed rural-urban differences in both menopausal age and reporting of menopausal problems (e.g., vasomotor, psychosomatic, psychological, and urinary problems). The linear regression (stepwise) result ...
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