vascular disruption
Prenatal Cocaine Exposure and Fetal Vascular Disruption
... some time, and that 5 million use cocaine regularly.1 It has been suggested in previous studies that ma- ternal cocaine use during pregnancy may result in fetal vascular disruption of th[r] ...
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Improving Nanoparticle Penetration in Tumors by Vascular Disruption with Acoustic Droplet Vaporization
... via vascular disrup- tion by various mechanical forces from oscillation, expansion, and collapse of microbubbles ...the vascular per- fusion and entraps drugs in tumor vessels ...of vascular ...
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A polymeric colchicinoid prodrug with reduced toxicity and improved efficacy for vascular disruption in cancer therapy
... promising vascular disrupting agents (VDAs) in cancer therapy, their dose-limiting toxicity has prevented any clinical application for this ...novel vascular disrupting ...and vascular disrupting ...
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Exogenous sickle erythrocytes combined with vascular disruption trigger disseminated tumor vaso-occlusion and lung tumor regression
... degree of vaso-occlusion and pimidazole-reactive hypoxic cells in the treated groups (Figure 2C). We next examined the effect of SR to the tumor alone or together with CA-4 or SSRBCs on tumor vaso-occlusion and hypoxia. ...
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Congenital Microcephaly Due to Vascular Disruption: In Utero Documentation
... Top right, US scan at 21 weeks’ gestation showing normal brain structures in surviving twin. Bot-[r] ...
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Enhancing Nanoparticle Accumulation and Retention in Desmoplastic Tumors via Vascular Disruption for Internal Radiation Therapy
... alongside vascular hemorrhage in the tumor, and it makes sense that if blood cells can enter the tumor center, the much smaller nanoparticles also slowly flowing through the broken vasculature would not be kept at ...
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Congenital Hydranencephaly/Porencephaly Due to Vascular Disruption in Monozygotic Twins
... The additional finding that 75% of cases were associated with a deceased co-twin may be important in understanding the relationship be- tween monozygotic twins and hydranencephaly/ poren[r] ...
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Vascular disruption and blood–brain barrier dysfunction in intracerebral hemorrhage
... In cerebral ischemia and other neurological conditions such as multiple sclerosis, there has been in depth in- vestigation of the mechanisms involved in leukocyte trans- migration into brain [50,102,103]. Transmigration ...
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Single low-dose lipopolysaccharide preconditioning: neuroprotective against axonal injury and modulates glial cells
... closed-head model of diffuse axonal injury. LPS preconditioning has previously been shown to be protective in penetrating models, but there was significant vascular disruption in these models and they were ...
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An Ongoing Epidemic of Birth Defects
... a vascular mechanism since miso- prostol has a major effect on ...to vascular constriction at a critical time in neuronal ...with vascular disruption defects ...
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Correlation of Prenatal and Postnatal MRI Findings in Schizencephaly
... has not been verified in further studies.6 The common pathophysiology of injury is frequently ascribed to a vascular disruption, hypoxia-ischemia, and/or prenatal infection at critical t[r] ...
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Computational and Experimental Investigation of Biofilm Disruption Dynamics Induced by High Velocity Gas Jet Impingement
... The ripple dynamics produced by turbulent flow over biofilms has been previously related to the viscoelastic nature of biofilms (5, 7, 38), suggesting that the biofilm mechanical response is dominated by the EPS matrix ...
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Myocardial necrosis due to vitamin D3 overdose - scanning electron microscopic observations
... significant disruption of the structural integrity of the myocardium linked to fragmentation of the cardiac muscle bundles and a visible disruption of the extracellular matrix (ECM) ...
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Managing supply chain disruptions: role of firm resilience and strategic focus on innovation
... chain disruption orientation and firm resilience in such ...chain disruption orientation and risk management infrastructure have a synergistic effect on firm ...chain disruption oriented firms ...
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Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation
... Recent studies in low-density lipoprotein receptor– deficient mice, which are hyperglycemic but exhibit no marked dyslipidemia when compared with nondiabetic controls, showed that diabetes in the absence of diabetes- ...
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Vascular estrogen receptors and endothelium derived nitric oxide production in the mouse aorta Gender difference and effect of estrogen receptor gene disruption
... of vascular tone in mouse aorta The present study shows that similar to blood vessels isolated from a variety of other species (30–34) the endothelium of the mouse aorta produces a vascular smooth muscle ...
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The Complete Makeover of Cloud Computing in the Next Decade, Will You Survive?: A Prophetic Approach
... Therefore, Forrester decided to focus instead on the major disruption in the IT industry that cloud computing is bringing about — disruption based not on technology but on the business m[r] ...
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Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice
... barrier disruption with acetone results in a 72% increase in epidermal TNF ...barrier disruption that avoids application of potentially toxic chemicals, TNF mRNA was elevated fivefold over controls at ...
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Disruption of Glycolysis by Nutritional Immunity Activates a Two Component System That Coordinates a Metabolic and Antihost Response by Staphylococcus aureus
... Successful pathogens have developed strategies that enable them to overcome host-imposed Mn limitation (28). These adaptations include expression of Mn-sensing regulators and high-affinity Mn transporters, altering ...
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A Novel Small Molecule, 1,3-di-m-tolyl-urea, Inhibits and Disrupts Multispecies Oral Biofilms
... nucleatum (Figure S2). Selective disruption of the biomass of the bridge colonizer F. nucleatum may explain the effects on multispecies biofilms. To confirm if disruption of[r] ...
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