vascular endothelial growth factor A
Role of vascular endothelial growth factor-A in collateral growth and development
... The signaling pathways that direct remodeling of pre-existing collaterals in ischemia remain unclear. 25 Few studies have addressed whether endogenous VEGF mediates collateral growth. Supportive evidence exists in ...
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Circulating protein biomarkers in systemic sclerosis related pulmonary arterial hypertension: a review of published data
... soluble vascular endothelial growth factor receptor 1; PlGF, placenta growth factor; VEGF-A, vascular endothelial growth factor A; GDF-15, ...
8
Effects of Interferon Alpha 2b on VEGFR 2, VEGFA, MAPK 1 and ERK 1 Gene Expression in Corneal Neovascularization Models
... on vascular endothelial growth factor receptor-2 (VEGFR-2), vascular endothelial growth factor-A (VEGFA), mitogen activated protein kinase-1 (MAPK-1) and ...
9
Association of the +936 C/T Single Nucleotide Polymorphism of the VEGF-A Gene with Renal Cell Cancer in an Eastern Indian Population
... the Vascular Endothelial Growth Factor, a protein which plays a major role in ...tumor growth and metastasis, as the newly formed blood vessels facilitate the transfer of the cancer ...
7
Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy
... VEGF-A; Vascular endothelial growth factor-A, VEGFR1; Vascular endothelial growth factor receptor 1, VEGFR2; Vascular endothelial growth ...
11
Vascular endothelial growth factor expression and vascular densi-ty in oral squamous cell carcinoma (OSCC): A study on clinical and histopathologic significance
... progression. Vascular density affects the clinical outcome and prognosis of malignant ...the Vascular Endothelial Growth Factor (VEGF) expression and vascular density with the ...
6
Emerging role of insulin-like growth factor-binding protein 7 in hepatocellular carcinoma
... of a triple-negative breast-cancer cell line (MDA-MB-231) with recombinant IGFBP7 protein induced G 1 cell-cycle arrest and senescence, as indicated by cell-cycle analysis and β -galactosidase staining, respectively. The ...
11
Comparative effectiveness of aflibercept for the treatment of patients with neovascular age-related macular degeneration
... anti-vascular endothelial growth factor (VEGF) therapies are now considered the standard of ...vessel growth, leading to vision ...multiple growth factors, is promising not only ...
7
Nintedanib: evidence for its therapeutic potential in idiopathic pulmonary fibrosis
... platelet-derived growth factor (PDGF)/PDGF receptor pathway is thought to play a critical role in fibrogenesis of the ...Other growth factors, including fibroblast growth factor and ...
10
VEGF 936C>T is predictive of threshold retinopathy of prematurity in Japanese infants with a 30-week gestational age or less
... Abstract: Vascular endothelial growth factor (VEGF) contributes to the development of retinopathy of prematurity (ROP). We investigated the association of ROP with VEGF genetic polymorphisms ...
7
Neovascular age-related macular degeneration: intraocular inflammatory cytokines in the poor responder to ranibizumab treatment
... Patients and methods: This is an observational, prospective study. Thirty-two eyes from 30 patients were included in the study: 11 patients who responded poorly to ranibizumab and were switched to aflibercept (AF group), ...
9
Soluble Vascular Endothelial Growth Factor Receptor 1 in Tracheal Aspirate Fluid of Preterm Neonates at Birth May Be Predictive of Bronchopulmonary Dysplasia/Chronic Lung Disease
... All of the infants with a birth weight of ⱕ 1500 g or born at ⬍ 30 weeks’ gestation, who were intubated within 24 hours because of respiratory failure, and who under- went assisted mechanical ventilation, were enrolled ...
9
Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential
... or vascular endothelial cells [53] and plays an important role in the amplification and mobilization of progenitor ...recruit endothelial progenitor cells at the site of tissue ...
12
Turmeric (Curcuma longa) Decoctum Had no Effect on Vascular Endothelial Growth Factor (VEGF) and Vascular Endothelial Cadherin (VE-cadherin) Expression in the Chick Embryo
... of endothelial cells, interrupt the formation of tubes and the vascular lumen, and disrupt vascular permeability, resulting in vascularization defects that interfere with embryo organogenesis ...
9
Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells
... Vascular endothelial growth factor (VEGF) is a mitogen with a specificity for endothelial cells in vitro and an angiogenic inducer in ...a growth advantage in ...
12
The autotaxin-lysophosphatidic acid–lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiforme
... most vascular human ...of vascular endothelial growth factor (VEGF)) was established, sufficient results have not been obtained because of the increased invasiveness triggered by ...
9
Caries Induced FGF 2 Expression in Human Dental Pulp
... regulatory factor in the control of vascular permeability and angiogenesis (Ferrara et ...enhance vascular permeability is estimated to be 50,000 times higher than histamine (Ferrara et ...2003). ...
89
Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy
... Willebrand factor; MCAO: middle cerebral artery occlusion; ET: endothelin; TNF: tumor necrosis factor; TIMP-1: tissue inhibitor of matrix metalloproteinases-1; EPO: erythropoietin; ACE2: angiotensin- ...
17
Effects of nicotine administration in rats on MMP2 and VEGF levels in periodontal membrane
... various growth factors de- pends on the expression of corresponding ...within vascular endothelial cells, neutrophils, plasma cells, and junctional, pocket and gingival epithelium ...and ...
7
New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management
... Long years of basic and clinical research have resulted in a switch from this repetitious iatrogenic intoxication of patients and their tumors to more targeted antineo- plastic “snipers”, which eliminate tumor cell ...
11