vascular endothelium
Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1
... components by cultured human vascular endothelium. Conditioned media collected from IL- 1-treated (5 U/ml, 24 h) monolayers exhibited decreased tissue-type plasminogen activator (tPA) activity and increased ...
6
Role of the vascular endothelium and plaque in acute ischemic stroke
... either directly to a stroke through occlusion of a cerebral artery or indirectly by the production of a distal thromboembolism. The list of risk factors for both atherosclerosis and stroke reads like a litany of modern ...
6
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
... To determine incorporation of SP cells into endothe- lial cells, approximately 100 vessel profiles were ana- lyzed per tissue section. Three to 11 tissue sections were counted per animal. As in the cardiac tissue, a ...
9
Shear Forces Enhance Toxoplasma gondii Tachyzoite Motility on Vascular Endothelium
... ABSTRACT Toxoplasma gondii is a highly successful parasite that infects approximately one-third of the human population and can cause fatal disease in immunocompromised individuals. Systemic parasite dissemination to ...
12
Vascular endothelium is critically involved in the hypotensive and hypovolemic actions of atrial natriuretic peptide
... in vascular endothelium, but the functional relevance of this is ...the endothelium-mediated actions of ANP in vivo, we inactivated the GC-A gene selectively in endothelial cells by homologous ...
10
Pressure-dependent regulation of Ca2+ signaling in the vascular endothelium
... The vascular endothelium is a one-cell-thick layer that directs the formation of new blood vessels (angiogenesis), prevents blood clotting, regulates vascular permeability, controls arterial tone and ...
23
PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis
... vascular endothelium. We chose to investigate Ang II, an important vascular mediator which acti- vates PKC1 in cardiomyocytes 23 and up-regulates HO-1 in ...
11
Active roles of dysfunctional vascular endothelium in fibrosis and cancer
... the endothelium has traditionally been regarded as a passive player in the pathogenic process, or even as a barrier since it provides a physical divide between the circulating immune cells and the inflamed ...
12
Gene silencing of E selectin block recruitment of endothelial progenitor cell to vascular endothelium under flow
... cubation with IL-1β induces adhesion of HL60 cells to HUVEC under flow; 2) 4 h of incubation with IL-1β induces expression of E-selectin and ICAM-1 in HU- VEC; 3) 4 h of incubation with IL-1β induces adhesion of EPCs to ...
6
Transport of Gold Nanoparticles by Vascular Endothelium from Different Human Tissues
... human vascular endothelia. Kidney endothelium (ciGENC) showed higher uptake of these nanoparticles than brain endothelium (hCMEC/D3), reflecting their biodistribution in ...kidney endothelium ...
17
The chemokine SDF 1 stimulates integrin mediated arrest of CD34+ cells on vascular endothelium under shear flow
... the vascular endothelium that lines the bone marrow (BM) ...on vascular endothelium of murine BM ...BM endothelium in the absence of endothelial selectins ...BM endothelium is ...
14
Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages
... and vascular cell adhesion molecule-1 (VCAM-1), and the production of the proinflammatory cytokine interleukin-6 (IL- ...human vascular cell functions relevant to athero- genesis and lesional ...
8
Specific binding of endocrine transforming growth factor beta 1 to vascular endothelium
... The presentation of recombinant biologically active 125I-TGF-beta 1 via the bloodstream to potential target cells in mice and rats was evaluated by quantitative light and electron microscope radioautography. Specificity ...
17
The Vascular Endothelium and Human Diseases
... The endothelium plays a crucial role in provid- ing the proper haemostatic ...the vascular wall that helps to maintain blood ...upon vascular injury and limit clot formation to the areas where ...
13
HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium
... containing HDL; HDL -ApoM : ApoM-lacking HDL; HUVEC: Human umbilical vein endothelial cells; S1P: Sphingosine 1-phosphate; S1PR: S1P receptor.. Acknowledgements.[r] ...
12
Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle
... in vascular cells and multiple agents have diverse actions which contribute to our understanding of their actions ...the vascular response to the anti-hyperglycaemic action of GKAs, and studies examining ...
15
Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia
... NO exerts its vasodilating effect in at least two ways: via previously described direct effects on the baseline tone of vascular smooth muscle; and, according to our findings, indirectly[r] ...
7
Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study
... Background: Macrophages may concentrate ultrasound contrast agents and exhibit selective adhesion to activated endothelium. The present study investigates in mice the potential of perfluorohexane (PFH) loaded ...
8
Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro
... Endotoxemia is frequently associated clinically with disseminated intravascular coagulation (DIC); however, the mechanism of endotoxin action in vivo is unclear. Modulation of tissue factor (TF) and thrombomodulin (TM) ...
8
Rolling and adhesion of human tumor cells on vascular endothelium under physiological flow conditions
... activated endothelial cells with a monoclonal antibody against E-selectin inhibited rolling and adhesion of HT-29M, but had no effect on the adhesion of A375M cells; monoclonal antibody against vascular cell ...
8