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Vascular Pathology

Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain

Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain

... acute vascular pathology 24–72 h after blast exposure ...of vascular-associated GFAP recover in Western blots to control levels at 8 months post-exposure, we do not know whether this reflects ...

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A Novel Cytomegalovirus Induced Regulatory Type T Cell Subset Increases in Size During Older Life and Links Virus Specific Immunity to Vascular Pathology

A Novel Cytomegalovirus Induced Regulatory Type T Cell Subset Increases in Size During Older Life and Links Virus Specific Immunity to Vascular Pathology

... Interestingly, the marked changes of the immune system in terms of composition and function, previously termed “ immune risk phenotype, ” include large CD8 + T-cell expan- sions that are believed to be CMV specific to ...

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Searching for transcriptional regulators of Ang II–induced vascular pathology

Searching for transcriptional regulators of Ang II–induced vascular pathology

... in vascular pathobiology, including inflammation and ...induces vascular cellular transcriptional activation and gene expression, but the mechanisms explaining its long-term tissue effects in vivo are ...

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Pathological Reacting To Meteorological Changes as a Risk-Factor of Cardio-Vascular Pathology in the North

Pathological Reacting To Meteorological Changes as a Risk-Factor of Cardio-Vascular Pathology in the North

... Cardio-vascular pathology is widespread in the ...cardio-vascular pathology in the ...cardio- vascular pathology (arterial hypertension I, II and coronary artery disease, stable ...

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Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review

Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review

... While autopsy studies minimize errors in diagnosis, neuropathological data may be limited in many important ways. Neuropathological data are themselves cross-sectional (that is, can only be collected once); it is diffi ...

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CT angiography versus Digital Subtraction angiography for intracranial vascular pathology in a clinical setting

CT angiography versus Digital Subtraction angiography for intracranial vascular pathology in a clinical setting

... structures/heavy vascular calcification (Patient 3 and 6) and lack of/inadequate VRT/MIP/bone subtracted images (Patient 4), prevented accurate diagnosis, even on further retrospective ...intracranial ...

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Contribution of blood platelets to vascular pathology in Alzheimer's disease

Contribution of blood platelets to vascular pathology in Alzheimer's disease

... Abstract: Cerebral amyloid angiopathy (CAA) is a critical factor in the pathogenesis of Alzheimer’s disease (AD). In the clinical setting, nearly 98% AD patients have CAA, and 75% of these patients are rated as severe ...

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Understanding the role of MasR in vascular pathology

Understanding the role of MasR in vascular pathology

... 10 derived vasoconstrictors are increased (12, 13) . The formation of lesions promoted by both early and late mechanisms of atherosclerosis, including increased chemokine secretion and leukocyte adherence, enhanced ...

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S Nitrosothiols signal hypoxia mimetic vascular pathology

S Nitrosothiols signal hypoxia mimetic vascular pathology

... Last, NAC-derived SNOAC is hypoxia-mimetic at the cellular level, whereas NAC itself opposes cellular effects associated with hypoxia (31, 32). SNOAC increases S-nitrosothiol levels in pri- mary pulmonary vascular ...

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Beyond mild cognitive impairment: vascular cognitive impairment, no dementia (VCIND)

Beyond mild cognitive impairment: vascular cognitive impairment, no dementia (VCIND)

... morbid vascular disease has been compared with that of individuals with MCI and no vascular disease, group differences have been reported in some [58,59], but not all [60], ...MCI vascular group ...

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“Urustambha” – Aortoiliac occlusion with Metabolic syndrome?

“Urustambha” – Aortoiliac occlusion with Metabolic syndrome?

... indicates vascular pathology like “aortoiliac occlusion” with an underlying “MS” whereas Sushruta’s version of Urustambha indicates inflammatory pathology of spinal cord like “ATM” or “inflammatory ...

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Autopsy study of sudden unexpected deaths

Autopsy study of sudden unexpected deaths

... Seven years retrospective study was done in pathology department in tertiary care center in which 150 cases were studied. After performing autopsy, organs were grossly examined, representative sections were taken, ...

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Severe Pulmonary Hypertension Caused by Smoldering Plasma Cell Myeloma: An Autopsy Case of POEMS Syndrome

Severe Pulmonary Hypertension Caused by Smoldering Plasma Cell Myeloma: An Autopsy Case of POEMS Syndrome

... pulmonary vascular pathology featuring plasma cell proliferation and provides clues to understanding the mechanism of PH in PCDs, a condi- tion whose pathogenesis should be considered heteroge- ...

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The overlap between vascular disease and Alzheimer’s disease - lessons from pathology

The overlap between vascular disease and Alzheimer’s disease - lessons from pathology

... AD pathology, were free of essential vascular pathology except for minor to moder- ate CAA (50%) and without CVLs, compared to ...similar vascular lesions [157]. Minor and moderate ...

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White matter hyperintensities are related to pain intensity in an outpatient memory clinic population: preliminary findings

<p>White matter hyperintensities are related to pain intensity in an outpatient memory clinic population: preliminary findings</p>

... A recent study in outpatient memory clinics has shown that older patients with Alzheimer ’ s disease (AD) and mixed dementia (MD; AD and vascular pathology) are less likely to report pain than older ...

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Age-associated changes in the blood brain barrier: Comparative studies in human and mouse

Age-associated changes in the blood brain barrier: Comparative studies in human and mouse

... While vascular pathology is a common feature of a range of neurodegenerative diseases, we hypothe- sized that vascular changes occur in association with normal ...lation), vascular ...

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Adipose stromal vascular fraction attenuates TH1 cell-mediated pathology in a model of multiple sclerosis

Adipose stromal vascular fraction attenuates TH1 cell-mediated pathology in a model of multiple sclerosis

... both SVF and ASC treatments. Furthermore, the microglia and macrophage populations were collectively increased in CNS tissues after ASC treatment, and the alternative activa- tion phenotype was most enhanced compared to ...

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MicroRNA 140 5p and SMURF1 regulate pulmonary arterial hypertension

MicroRNA 140 5p and SMURF1 regulate pulmonary arterial hypertension

... miR-140-5p regulates key mediators of PAH pathogenesis. Path- way analysis of miR-140-5p targets identified overrepresentation in pathways related to PAH pathology (Supplemental Table 6). To refine potential ...

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Inguinoscrotal pathology

Inguinoscrotal pathology

... tend not to vary in size, but may increase in volume over time. Usually, they are tense and the underlying testis is not easily palpated. Since such hydroceles may be secondary to underlying testicular pathology ...

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The Pathology of addiction

The Pathology of addiction

... In summation, a brain with a nucleus accumbens hypersensitive to dopamine as a result of the glucocorticoids released because of chronic inescapable stress, in conjunction with low basel[r] ...

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