vascular smooth muscle
Vascular smooth muscle cell (VSMC) proliferation has
... human vascular smooth muscle cells (VSMCs) are affected by the expression of simian virus 40 (SV40) large T antigen (LT antigen), which binds to cell cycle regulators such as the tumor suppressor ...
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Stretching Vascular Smooth Muscle Cells on Micropatterned Surfaces
... artery smooth muscle cells, ...24] Vascular smooth muscle cells produce their own reticular network of ECM protein fibers, including elastin and collagen types I and III 26 ...
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Emerging regulators of vascular smooth muscle cell migration
... Abstract Vascular smooth muscle cells (VSMCs) are the predominant cell type in the blood vessel wall and normally adopt a quiescent, contractile ...
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Abnormal vascular smooth muscle cell (VSMC) proliferation
... 31. Derman MP, Cunha MJ, Barros EJG, Nigam SK, Cantley LG. HGF- mediated chemotaxis and tubulogenesis require activation of the phos- phatidylinositol 3-kinase. Am J Physiol. 1995;37:F1211–F1217. 32. Bilato C, Pauly RR, ...
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Rapamycin inhibits vascular smooth muscle cell migration
... Abnormal vascular smooth muscle cell (SMC) proliferation and migration contribute to the development of restenosis after percutaneous transluminal coronary angioplasty and accelerated arteriopathy ...
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The Role of Cellular Architecture in Vascular Smooth Muscle Function and Mechanics
... of vascular smooth muscle architecture in the function of healthy and dysfunctional vessels is poorly ...between vascular smooth muscle architecture and contractile output using ...
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IP3 receptors regulate vascular smooth muscle contractility and hypertension
... regulating vascular smooth muscle cell (VSMC) contraction for ...a smooth muscle–specific IP 3 R triple-knockout (smTKO) mouse model using a tamoxifen-inducible ...aortic ...
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-induced injury of human vascular smooth muscle cells (HVSMCs)
... Received October 11, 2017; Accepted October 30, 2017; Epub December 1, 2017; Published December 15, 2017 Abstract: Thoracic aortic dissection is a catastrophic acute aortic disease with a high postoperative mortality. ...
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The regulation of myocardin factor dependent transcription in vascular smooth muscle
... NTRODUCTION Vascular smooth muscle cells (SMC) play a critical role in vasculogenesis and angiogenesis, and provide mature vessels with the capacity for contraction necessary for proper maintenance ...
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A novel vascular smooth muscle chymase is upregulated in hypertensive rats
... rat vascular smooth muscle ...rat vascular chymase is encoded by a separate ...artery smooth muscle cells from sponta- neously hypertensive than in corresponding tissues from ...
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A novel vascular smooth muscle chymase is upregulated in hypertensive rats
... rat vascular smooth muscle ...rat vascular chymase is encoded by a separate ...artery smooth muscle cells from sponta- neously hypertensive than in corresponding tissues from ...
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Hypotension Due to Kir6.1 Gain-of-Function in Vascular Smooth Muscle
... artery smooth muscle cells from the GD and GD-QR DTG offspring of CX1 transgenic mice and SMMHC-Cre-ER ...targeted vascular tissue, quantitative real time PCR shows the copy number of transgene in ...
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Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells
... . Vascular calcification is an active process, promoted by vascular smooth muscle cells (VSMCs) 6 ...ameliorates vascular calcification 11 ...of vascular calcification 1 . The ...
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The Influence of Caldesmon Suppression on Proliferation and Motilities of Vascular Smooth Muscle Cells
... of vascular smooth muscle cells (VSMCs) from the media to intima constitutes a critical step in the development of proliferative vascular ...
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Spatial Distribution of Cytoskeletal Mechanical Properties in Vascular Smooth Muscle Cells
... This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract The mechanical properties on a whole basis of cell are extensively studied ...
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Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia
... Troglitazone Inhibits Vascular Smooth Muscle Cell Growth and Intimal Hyperplasia Ronald E. Law,* Woerner P. Meehan,* Xiao-Ping Xi,* Kristof Graf,* i Daniel A. Wuthrich, § William Coats, ‡ David ...
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Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells
... Treatment of quiescent RASMCs with 1 mM homocysteine or 2% calf serum for 36 h increased cyclin A mRNA levels by 8- and 14-fold, respectively, whereas homocysteine plus serum increased cyclin A mRNA levels by 40-fold, ...
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Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells
... proliferative effect of 1% and 5% serum as measured by 3H-thymidine incorporation and cell number, confirming ANP as an antimitogenic factor. In quiescent RASM cells, ANP (10(-7), 10(-6) M) significantly suppressed the ...
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NOX4 downregulation leads to senescence of human vascular smooth muscle cells
... as well as detrimental effect, depending on the cell context and stimuli that influence its activity. The aim of these studies was to investigate the role of NOX4 in the senescence of human vascular smooth ...
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Specific binding of endothelin on human vascular smooth muscle cells in culture
... human vascular smooth muscle cells obtained from umbilical ...per smooth muscle ...vein smooth muscle cells possess specific binding sites for endothelin, and that human ...
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