Vascular smooth muscle cell (VSMC)
MiR-93 regulates vascular smooth muscle cell proliferation, and neointimal formation through targeting Mfn2
... Background/Aims: Vascular smooth muscle cell (VSMC) hyperplasia plays important roles in the pathogenesis of many vascular diseases, such as atherosclerosis and ...rat ...
12
Rapamycin inhibits vascular smooth muscle cell migration
... Abnormal vascular smooth muscle cell (SMC) proliferation and migration contribute to the development of restenosis after percutaneous transluminal coronary angioplasty and accelerated ...
8
Interleukin-32α Inhibits Endothelial Inflammation, Vascular Smooth Muscle Cell Activation, and Atherosclerosis by Upregulating Timp3 and Reck through suppressing microRNA-205 Biogenesis
... Since IL-32α was unable to affect the biological functions of miR-205, we speculated that it might inhibit miR-205 expression by regulating miRNA biogenesis. Thus, we first investigated whether IL-32α affected the ...
18
MicroRNA-186-5p serves as a diagnostic biomarker in atherosclerosis and regulates vascular smooth muscle cell proliferation and migration
... Results: Serum expression of miR-186-5p was significantly higher in atherosclerosis patients than in the control group. The serum miR-186-5p level showed a positive correlation with CIMT and could be used to distinguish ...
9
Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By Extracellular Matrix Stiffness
... and cell types, and that stiffness significantly dictates VSMC transcriptional identity over contributions from embryologic ...stiffness-dependent VSMC proliferation and ...the VSMC ...
157
Original Article MicroRNA-1 promotes apoptosis of cerebral vascular smooth muscle cells in intracranial aneurysm through targeting Bcl-2
... cerebral vascular smooth muscle cell (VSMC) through inhibiting Bcl-2 in the pathogenesis of intracranial aneurysm ...Bcl-2. Cell proliferation was determined through using CCK-8 ...
8
A role for focal adhesion kinase in vascular smooth muscle cell proliferation, migration and differentiation
... cardiac muscle cells, SMC do not terminally differentiate and retain the genetic plasticity that enables them to transition from a highly contractile phenotype to synthetic ...various vascular pathologies, ...
203
Angiotensin (1-7) and Alamandine: Similarities and differences
... (NO, nitric oxide; VSMC, vascular smooth muscle cell; Red line, blocking effect; Green line, activation). 240[r] ...
19
A complex role for the progesterone receptor in the response to vascular injury
... in vascular biology has not been studied in ...greater vascular medial hypertrophy and vascular smooth muscle cell (VSMC) proliferation in response to vascular ...
9
The extracellular signal regulated kinase (ERK) pathway: a potential therapeutic target in hypertension
... of vascular smooth muscle cells, which can lead to a thickening of the smooth muscle layer of the blood vessels and a reduction in lumen ...increased vascular smooth ...
7
The angiotensin AT2 receptor mediates inhibition of cell proliferation in coronary endothelial cells
... for vascular smooth muscle cells and fibroblasts but little is known about its influence on growth in endothelial ...rat vascular smooth muscle cells (VSMC) was determined ...
8
Patent ductus arteriosus in mice with smooth muscle specific Jag1 deletion
... for smooth muscle cells (orange, anti-SM22a antibody) and endothelial cells (green, anti- PECAM1 antibody) revealed reduced vascular smooth muscle cell differentiation in the ...
9
Protective Effect of Pyrogallol-phloroglucinol-6,6-bieckol from Ecklonia cava on Monocyte-Associated Vascular Dysfunction
... associated vascular smooth muscle cell proliferation and migration by decreasing the 25.. phosphorylations of ERK and AKT.[r] ...
11
Electrospinning of poly (ester amide) fibres for mesenchymal progenitor cell differentiation
... primary vascular smooth muscle cells (VSMC) and endothelial cells (ECs) due to their increased proliferative capacity compared to differentiated primary cells, their ability to differentiate ...
121
Interaction of Vascular Smooth Muscle Cells with Collagen Impregnated Embolization Coils Studied with a Novel Quantitative in Vitro Model
... of VSMC adhe- sion to the device and that cell adhesion preferentially occurs in areas of exposed ...potent VSMC chemotaxin and that fibrillar type I col- lagen strongly promotes the adhesion of ...
8
Immune interferon inhibits proliferation and induces 2' 5' oligoadenylate synthetase gene expression in human vascular smooth muscle cells
... stimulated with the well-defined mitogens IL 1 (from 15.3 +/- 0.7 to 6.2 +/- 0.7 dpm X 10(- 3)/24 h) or platelet-derived growth factor (PDGF) (from 18.5 +/- 1.0 to 7.3 +/- 0.7 dpm X 10(- 3)/24 h). Kinetic and nuclear ...
10
Evaluation of the anti angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit
... several cell types such as endothelial cells (ECs), vascular smooth muscle cells (VSMCs), macrophages, which should be activated, pro- liferate and migrate to invade the extracellular matrix ...
10
Insulin and insulin like growth factor I differentially induce alpha1 adrenergic receptor subtype expression in rat vascular smooth muscle cells
... T2, cell culture medium, insulin and recombinant human IGF-I, Optim-MEM medium, lipofectamine and newborn bovine serum from Gibco/BRL (Grand Island, NY); collagenase (CLS-IV) from Worthington Biochemical ...
10
Phosphorylation of PRH/HHEX by Protein Kinase CK2 Regulates Cell Proliferation and Cell Migration in Diverse Cell Types
... control cell proliferation and cell migration results in multiple disease states including cancer and ...controls cell proliferation and cell migration in a variety of tissues in the adult and ...
21
Identification of the mechanism for the inhibition of Na+,K(+) adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2
... enzymatic activity were inhibited by the PKC inhibitor GFX. In contrast, elevation of glucose levels decreased Na+,K(+)-ATPase activity as measured by ouabain-sensitive 86Rb uptake by twofold in rat VSMC. ...
9