vasculogenic mimicry
Vasculogenic Mimicry in Primary Breast Carcinoma - a Potential Antiangiogenic Target: Frequency and Morphological Characteristics
... Angiogenesis is a process essential for tumor progression [1]. Presently several different mechanisms of tumor vascularisation including sprouting angiogenesis, intussusceptive angiogenesis, recruitment of endothelial ...
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Vasculogenic mimicry contributes to lymph node metastasis of laryngeal squamous cell carcinoma
... results. Vasculogenic mimicry is one example of the remarkable plasticity demonstrated by aggressive melanoma cells and suggests that these cells have acquired an embryonic-like ...
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<p>Advances and Prospects of Vasculogenic Mimicry in Glioma: A Potential New Therapeutic Target?</p>
... VM, vasculogenic mimicry; ECs, endothelial cells; GCs, glioma cells; PAS, Periodic Acid-Schiff; 3D, three- dimensional; GSCs, glioma stem cells; VEGF, vascular endothelial growth factor; VEGFR-2, vascular ...
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CD133 cancer stem-like cells promote migration and invasion of salivary adenoid cystic carcinoma by inducing vasculogenic mimicry formation
... CD133+ cancer stem-like cells promote migration and invasion of salivary adenoid cystic carcinoma by inducing vasculogenic mimicry formation Sha-sha Wang1, Xiao-lei Gao1, Xin Liu1, Shi-y[r] ...
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Original Article The expressions of CD133, ALDH1, and vasculogenic mimicry in osteosarcoma and their clinical significance
... Abstract: Background and purpose: Osteosarcoma is an aggressive malignant bone tumor in children and adoles- cents, which is more likely to recur and metastasize at the early stages. Cancer stem cells (CSC, CD133 is a ...
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Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome
... In this context, much attention has recently focused on vasculogenic mimicry (VM), the formation of vascular networks directly by tumor cells [3, 4]. In VM, hollow channels and narrow conduits within tumors ...
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Original Article Expression of LGR5 in oral squamous cell carcinoma and its correlation to vasculogenic mimicry
... cancers. Vasculogenic mimicry (VM) which defines the formation of fluid-conducting tubes by highly progressive and genetically dysregulated cancer cells has been considered as useful biomarker for ...
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Glioblastoma vasculogenic mimicry: signaling pathways progression and potential anti-angiogenesis targets
... Glioblastoma (GBM) is a highly angiogenic malignancy that is resistant to standard therapy; neo-formed vessels of this aggressive malignancy are thought to arise by sprouting of pre-existing brain capillaries. However, ...
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Original Article The correlation of KAI1, Slug and vasculogenic mimicry in the prediction of metastasis and prognosis in colorectal carcinoma
... Abstract: KAI1 and the epithelial-mesenchymal transition regulator Slug, as well as vasculogenic mimicry (VM), play a significant role in the process of metastasis and prognosis in many human cancers. This ...
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Dual effects of collagenase-3 on melanoma: metastasis promotion and disruption of vasculogenic mimicry
... Vasculogenic mimicry (VM) is a functional microcirculation formed by tumor cells. Matrix metalloproteinases (MMPs), especially MMP-2 and MMP-9, promote VM formation. Another specific MMP, collagenase-3 ...
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Destruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain glioma
... Abstract: The efficacy of chemotherapy for brain glioma is restricted by the blood–brain barrier (BBB), and surgery or radiotherapy cannot eliminate the glioma cells because of their unique location. Residual brain ...
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Original Article Correlation of KAI1, CD133 and vasculogenic mimicry with the prediction of metastasis and prognosis in hepatocellular carcinoma
... Vasculogenic mimicry (VM) is a new blood sup- ply phenomenon. It is a vascular channel struc- ture produced by some highly aggressive tumor cells that are present in malignant tumors, such as prostatic ...
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Claudin-4 is required for vasculogenic mimicry formation in human breast cancer cells
... Vasculogenic mimicry (VM) refers to the unique capability of aggressive tumor cells to mimic the pattern of embryonic vasculogenic networks. Claudins are aberrantly expressed in aggressive breast ...
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Zoledronic acid inhibits vasculogenic mimicry in murine osteosarcoma cell line in vitro
... and vasculogenic mimicry are ...a vasculogenic mimicry network, an in vivo or ex-vivo model should be established in future ...affecting vasculogenic mimicry ...
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Original Article Association of Notch1 with vasculogenic mimicry in human hepatocellular carcinoma cell lines
... tumor cells in tumor tissues exhibited endothe- lial features, cell sorting was not necessary before tube formation assay as in the case of the cell lines BEL-7402 and HCCLM6 [26]. First of all, we assumed that since the ...
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Original Article Erythropoietin and erythropoietin receptor in hepatocellular carcinoma: correlation with vasculogenic mimicry and poor prognosis
... and vasculogenic mimicry (VM) were reported to participate in tumor blood supply [7, ...of vasculogenic mimicry decreased and the number of endothelial-dependent ves- sels increased during ...
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Original Article Role of Bcl-2 and its associated miRNAs in vasculogenic mimicry of hepatocellular carcinoma
... in vasculogenic mimicry (VM) in hepatocellular ...with vasculogenic mimicry were ...of vasculogenic mimicry (VM) related molecules VEGF and HIF1A, which were target genes of the ...
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Evaluation of the correlation of vasculogenic mimicry, ALDH1, KiSS-1, and MACC1 in the prediction of metastasis and prognosis in ovarian carcinoma
... (EOC). Vasculogenic mimicry (VM; blood supply development often seen in highly aggressive cancers), aldehyde dehydrogenase 1 (ALDH1, cancer stem cell biomarker), KiSS-1 (suppressor of tumor metastasis), and ...
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Function of AURKA protein kinase in the formation of vasculogenic mimicry in triple-negative breast cancer stem cells
... cell vasculogenic mimicry (VM), a newly defined pattern of tumor blood supply, signifies the functional plasticity of aggressive cancer cells forming vascular ...cells, vasculogenic mimicry, ...
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Evaluation of the correlation of vasculogenic mimicry, ALDH1, KAI1 and microvessel density in the prediction of metastasis and prognosis in colorectal carcinoma
... reported vasculogenic mimicry (VM) [18], a new blood supply is a vascular channel-like struc- ture that is lining of cancer ...and vasculogenic-like channel to the host microcirculation system [19 – ...
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