VEGF receptors
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
... Because VEGF is a trophic factor required for the survival of endothelial cells and is abun- dantly expressed in the lung, we hypothesized that chronic blockade of VEGF receptors could induce ...
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Onofri, Chiara (2006): Localization and functional study of VEGF receptors in normal and adenomatous pituitary: evidence for a non-angiogenic role of VEGF. Dissertation, LMU München: Fakultät für Biologie
... metastases, VEGF-C and its receptor expression was also studied in order to obtain a more complete overview of VEGF receptors expression pattern in normal and tumoural human ...confirmed ...
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Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis
... whether VEGF may play a role in angiogenesis, we have determined the spatial and temporal patterns of expression of VEGF and VEGF receptors during natural angiogenic processes taking place ...
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Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia Modulation of gene expression by nitric oxide
... of VEGF and of the VEGF receptors KDR/Flk and ...of VEGF, KDR/Flk, and Flt and the amount of VEGF ...increased VEGF and KDR/flk hybridization signals in lungs from chronically ...
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Polymorphisms of VEGF and VEGF receptors are associated with the occurrence of ovarian hyperstimulation syndrome (OHSS)—a retrospective case–control study
... the VEGF-405 SNP and OHSS development confirms and ex- tends previous findings by Hanevik et ...the VEGF-405 genotype, these findings also open the possibility of a correlation between other fertility- ...
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Palm tocotrienols decrease levels of pro-angiogenic markers in human umbilical vein endothelial cells (HUVEC) and murine mammary cancer cells
... IL-6, VEGF and VEGF receptors were investigated in a cell-based system using human umbilical vein endothelial cells (HUVECs), 4T1 mouse mammary cancer cells as well as in a mouse ...
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Selective stimulation of VEGFR 1 prevents oxygen induced retinal vascular degeneration in retinopathy of prematurity
... of VEGF receptors are separable, it will be pos- sible to devise therapies for newborns that promote retinal capillary survival without inducing vasopro- ...the VEGF-A receptor tyrosine kinases, ...
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Dynamics of soluble vascular endothelial growth factor receptors and their ligands in aqueous humour during ranibizumab for age-related macular degeneration
... a VEGF trapping agent (aflibercept) ...with VEGF. Vitreous fluid levels of soluble VEGF receptor (sVEGFR)-1 and sVEGFR-2 are reported to be elevated in ischemic vitreoretinal diseases [6], and these ...
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Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability
... inhibitor treatment past the 9-hour time point. We also determined that treatment with NRP-1 inhibitor did not alter viral loads when compared to treatment with PBS using quantitative real time (RT)-PCR to detect viral ...
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PREDICTIVE VALUE OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN WOMEN UNDERGOING INTRACYTOPLASMIC SPERM INJECTION WITH HIGH RISK FOR OVARIAN HYPERSTIMULATION SYNDROME
... of VEGF receptors. In some studies, the gap between VEGF and receptors is necessary for developing OHSS, and the VEGFR-2 inhibitor, like the dopamine agonist, can reverse hCG action on ...
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Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion
... (VEGF), VEGF receptors, Endoglin, and Goosecoid, are known to be important in the control of cell proliferation and cell survival and/or the regulation of cell migration and ...
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Virus-Induced Decline in Soluble Vascular Endothelial Growth Receptor 2 Is Associated with Plasma Leakage in Dengue Hemorrhagic Fever
... VEGF receptors and, consequently, changes in vascular per- meability. Although our findings suggest a model in which viral infection of endothelial cells leads to changes in membrane and sVEGFR2 (Fig. 7), ...
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Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels
... that VEGF-C and VEGF-D from both SC and OM correlated negatively with the HOMA index (Figure ...between VEGF-A and HOMA, no correlations was observed in both OM and ...between VEGF isoforms ...
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Effects of hypoxia and hyperoxia on the differential expression of VEGF A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)
... Additional file 4: Figure S3. Expression of VEGF-A receptor and co- receptor mRNA and proteins in response to hypoxia and hyperoxia in normal (NF) and fibrotic (FF) fibroblasts. a) Quantitative RT-PCR of VEGFR1, ...
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Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells
... major VEGF-A isoform present in NSCLC cells, and the expres- sion of VEGF189 mRNA, in NSCLC cells, was 5 to 10 times higher than that of VEGF165 mRNA ...These VEGF isoforms probably have different functions ...
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Treatment failure in neovascular age-related macular degeneration is associated with a complex chemokine receptor profile
... All newly diagnosed patients received a standard treatment regimen of three intravitreal anti-VEGF injec- tions at 1-month intervals (‘loading dose’) followed by a clinical control approximately 2 months after the ...
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Original Article Overexpression of both VEGF-A and VEGF-C in gastric cancer correlates with prognosis, and silencing of both is effective to inhibit cancer growth
... and VEGF-C are two important molecules involv- ing in tumor development and metastasis via angiogenesis and ...of VEGF-A and VEGF-C on the growth of gastric cancer (GC) is not ...of VEGF-A and ...
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Matrix and plasma derived peptides promote tissue specific injury responses and wound healing in diabetic swine
... (VEGFA), VEGF receptor 1 and 2 (VEGFR1/2), and fibroblast growth factor-2 (FGF2), immune and stem cell chemoattractants including stromal cell-derived factor 1α (SDF1α) and chemokine (C-X-C motif) receptor-4 ...
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Recurrent Implantation Failure: The Role of the Endometrium
... The postovulatory rise of progesterone triggers profound changes in the epithelial cells, stromal cells and the matrix and blood vessels of the endo- metrium (47). The process of remodeling trigger- ed and controlled by ...
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The Role of Neurotransmitters in Anesthesia
... It is one of the major inhibitory neurotransmitters in posterior areas of the central nervous system, spinal cord, brainstem, and retina. In the spinal cord and brain stem, glycinergic interneurones provide an inhibitory ...
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