Ventilation-induced lung injury
Effect of intermittent ventilation pretreatment on one-lung ventilation-induced lung injury in radical operation for lung cancer as well as HIF-1α/ HO-1 expression
... one-lung ventilation-induced lung injury by intermittent ventilation pretreatment [13,14] , but the relationship between endoplasmic reticulum stress (ERS) and intermittent ...
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Original Article Role of notch signaling pathway in mechanical ventilation induced lung injury
... mechanical ventilation and its role in mechanical ventilation and lung ...mechanical ventilation at high tidal volume (VT = 20 ml/kg) for 4 hours. Lung injury and inflammatory ...
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Upregulation of the tight junction protein occludin: effects on ventilation-induced lung injury and mechanisms of action
... levels induced by ...ml/kg ventilation for 4 h and with low VT of 7 ml/kg as a ...the lung tissues of rats in the H group showed severe edema, alveo- lar hemorrhage and destroyed pulmonary ...
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Original Article TLR4 contributes to mechanical ventilation induced lung injury in the rabbits
... acute lung injury occurrence and ...ventilator-associated lung injury remains ...the lung tissue subjected to mechanical ventilation and explore the relationship between TLR4 and ...
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Parecoxib reduced ventilation induced lung injury in acute respiratory distress syndrome
... Both inflammation and the oxidative stress response can result in apoptosis, and apoptosis of endothelia and epithelia cells play a pivotal role in VILI [25, 41]. In the current study, we found that apoptosis was ...
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Early biomarkers and potential mediators of ventilation-induced lung injury in very preterm lambs
... 189, Santa Cruz Biotechnology, California, USA) diluted in DAKO antibody diluent (CYR61, diluted 1:150; EGR1 diluted 1:200) for either 90 min at room temperature (CYR61) or overnight at 4°C (EGR1). Sections were then ...
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Original Article Protective effects of low tidal volume mechanical ventilation associated with WISP1 -TRL4 signaling pathway in a sepsis model of mice
... acute lung injury ...decreasing ventilation induced lung injury (VILI) demonstrating protective ...mechanical ventilation and evaluate whether the protective effects of ...
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Cardiorespiratory effects of spontaneous breathing in two different models of experimental lung injury: a randomized controlled trial
... non-aerated lung tissue observed in the spiral CT scans has already been shown by others ...these lung areas by SB contributed to the improvement in oxygenation, regardless of ALI ...dependent lung ...
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Mechanical ventilation using non injurious ventilation settings causes lung injury in the absence of pre existing lung injury in healthy mice
... Mechanical ventilation (MV) may cause ventilator- induced lung injury ...gross lung injury and haemodynamic ...of lung structures and shock, and preventing metabolic ...
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The time-controlled adaptive ventilation protocol: mechanistic approach to reducing ventilator-induced lung injury
... acute lung injury, the method of treating sepsis-induced ARDS, the novel method of assessing alveolar inflation, the method of reducing blood loss associated with cardiopulmonary bypass, minimally ...
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Antenatal and postnatal corticosteroid and resuscitation induced lung injury in preterm sheep
... airway injury seen with initiation of ventilation ...of ventilation. Clearance of lung fluid prior to ventilation in the betamethasone group may have resulted in a more even ...
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The effects of exogenous surfactant administration on ventilation-induced inflammation in mouse models of lung injury
... the injury. Moreover, ex vivo ventilation of perfused lungs did not favor the use of severe lung injury models, due to potential technical failure of the prepar- ...the injury from ...
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Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin
... intestinal injury in VILI-driven ...gut injury in staphylococcal α-toxin induced shock, in polymicrobial sepsis or in gut ischemia and reperfusion ...intestinal injury accompanied by ...
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Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics
... in lung volume could deactivate surfactant by any of the following mechanisms: direct inhibition [16,22], increased surfactant release from type II cells with subsequent removal from the alveolar surface ...
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Hydrogen inhalation ameliorates ventilator induced lung injury
... In our study, hydrogen inhalation ameliorated upregu- lation of the mRNAs for TNFa, IL-1b, Egr-1, and CCL2 after 2 hours of MV, and this may explain the anti- inflammatory mechanisms afforded by hydrogen in this VILI ...
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Budesonide ameliorates lung injury induced by large volume ventilation
... We also found that budesonide decreased the TNF-α, IL- 1β, IL-6, and elastase levels and increased the IL-10 level in VILI. These results are consistent with those of previous stud- ies [16, 29]. It has been shown that ...
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Low tidal volume pressure support versus controlled ventilation in early experimental sepsis in pigs
... mitigate lung injury through sponta- neous ventilation vary between several studies and are not fully elucidated ...lavage-induced lung injury PSV was beneficial only in mild ...
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Low-molecular-weight heparin reduces hyperoxia-augmented ventilator-induced lung injury via serine/threonine kinase-protein kinase B
... tidal-volume ventilation is safer than high-tidal-volume ventilation, these findings have been questioned and the mechanisms of injury and protection need to be further examined ...Heart, Lung ...
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Extra corporeal membrane oxygenation to facilitate lung protective ventilation and prevent ventilator-induced lung injury in severe Pneumocystis pneumonia with pneumomediastinum: a case report and short literature review
... non-invasive ventilation for respiratory ...ultra-protective lung ventilation and prevented progression of pneumomediastinum, maintaining optimal gas ...
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Mechanical ventilation causes diaphragm dysfunction in newborn lambs
... To our knowledge, the question of whether the use of controlled MV triggers the biochemical and physio- logical alterations of VIDD in the neonatal diaphragm has not been addressed. Our investigation is also the first to ...
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