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vesicular trafficking

pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking

pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking

... dynein/dynactin-dependent trafficking of vesicles, such as brain-derived neurotrophic factor (BDNF)-containing vesicles, and of organelles, including reforming and maintenance of the Golgi near the cell ...these ...

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Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism

Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism

... implicated vesicular trafficking of BDNF via secretory vesicles, and both secretory and endosomal trafficking of vesicles containing synaptic proteins, such as neurotransmitter and neurotrophin ...

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Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry

Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry

... intracellular trafficking, like SNX17, which is involved in vesicular trafficking, and DYNLT1 and DYNLT3, components of the dynein motor protein complex ...

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Vesicular Trafficking of Incoming Human Papillomavirus 16 to the Golgi Apparatus and Endoplasmic Reticulum Requires γ Secretase Activity

Vesicular Trafficking of Incoming Human Papillomavirus 16 to the Golgi Apparatus and Endoplasmic Reticulum Requires γ Secretase Activity

... of vesicular compartments—the endosome, the Golgi apparatus, and the ER— during the journey of HPV16 to the ...retrograde vesicular transport of HPV components to the Golgi apparatus (27, 28) and by L2 ...

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Studies of a phosphatidylinositol 3-kinase complex linked to vesicular trafficking in human cells

Studies of a phosphatidylinositol 3-kinase complex linked to vesicular trafficking in human cells

... The expression of pl50(EE) in COS-7 cells however, does not appear to functionally alter the p i 50 protein, since it retains its ability to associate with Ptdlns 3- kina[r] ...

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Nipah Virus-Like Particle Egress Is Modulated by Cytoskeletal and Vesicular Trafficking Pathways: a Validated Particle Proteomics Analysis

Nipah Virus-Like Particle Egress Is Modulated by Cytoskeletal and Vesicular Trafficking Pathways: a Validated Particle Proteomics Analysis

... While recent studies have helped to clarify how Nipah virus assembly and budding occur, many gaps in our understanding remain. While paramyxovirus matrix proteins are generally accepted as crucial for driving particle ...

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Regulation of MTMR2 by Phosphorylation: Subcellular Characterization and Functional Role in Vesicular Trafficking

Regulation of MTMR2 by Phosphorylation: Subcellular Characterization and Functional Role in Vesicular Trafficking

... EGFR trafficking following EGF stimulation with these mutants in order to definitively identify the localization of the active receptors with respect to particular stage of ...

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Vesicular trafficking in osteoblasts

Vesicular trafficking in osteoblasts

... Alkaline phosphatase expression in rat calvaria sections indicated that cells on the trabecular bone surface expressing cadherin had an osteoblastic phenotype (fig. 4.9). 4.4[r] ...

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Identification and Characterization of Genes Required for Cell-to-Cell Fusion in Neurospora crassa

Identification and Characterization of Genes Required for Cell-to-Cell Fusion in Neurospora crassa

... homologous to the adv-1 gene (32). Our data suggest that these genes regulate the synthesis of proteins needed for cell fusion. Mutations in the ada-1 (NCU00499) and ada-2 (NCU02017) transcription factors have been shown ...

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Vesicular traffic at the cell membrane regulates oocyte meiotic arrest

Vesicular traffic at the cell membrane regulates oocyte meiotic arrest

... intracellular trafficking events (such as ER to Golgi) are unaffected (Leaf et ...that vesicular trafficking at the cell membrane is crucial not only for maintaining meiotic arrest but also for early ...

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CP110 and its network of partners coordinately regulate cilia assembly

CP110 and its network of partners coordinately regulate cilia assembly

... addition, vesicular trafficking, mother centri- ole/basal body migration to the cell surface, basal body anchoring to the cell membrane, and IFT must be tightly regulated in a temporally-, spatially-, and ...

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Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice

Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice

... Huntingtin interacting protein 1 related (Hip1r) is an F-actin– and clathrin-binding protein involved in vesicular trafficking. In this study, we demonstrate that Hip1r is abundantly expressed in the ...

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Regulation of localization and function of the Rho family small GTPase, Rnd3

Regulation of localization and function of the Rho family small GTPase, Rnd3

... Rho proteins have been shown to regulate numerous cellular functions such as cytoskeleton regulation, cell adhesion, cell polarity, endocytosis, vesicular trafficking[r] ...

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RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development

RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development

... Although LY294002 has been broadly used as a Class I PI3K inhibitor, this compound can also target other signalling cascades such as Class III PI3K [39]. Therefore, further analyses were performed with additional ...

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Revisiting the membrane-centric view of diabetes

Revisiting the membrane-centric view of diabetes

... betics: vesicular trafficking (including insulin secretion by beta cells [43]), glucose transport [44], endocytosis [45, 46], regulation of metabolic rate [47], platelet aggre- gation [20], ...

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PRONIOSOME: A NOVEL POLYMERIC VESICULAR DRUG CARRIER

PRONIOSOME: A NOVEL POLYMERIC VESICULAR DRUG CARRIER

... The main aim of novel vesicular drug delivery system is to deliver the drug in the body at specific site during the period of treatment. Drug encapsulation in the vesicles is one such system which helps to prolong ...

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Sex Trafficking: A Gender Based Civil Rights Violation

Sex Trafficking: A Gender Based Civil Rights Violation

... sex trafficking from the hands of their profiteers and victimizers and taking them to safety and ...anti- trafficking organizations and efforts into a real “abolition movement”, is the attention and ...

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Swedish Gender Equality for Trafficked Women? Radical Official Remedies and Ethnic Otherness

Swedish Gender Equality for Trafficked Women? Radical Official Remedies and Ethnic Otherness

... of trafficking is acknowledged in the preparatory work for the specific rules of the Aliens Act, and the relation between the trafficker and the trafficked woman is recognized as a power ...

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Asylum for Trafficked Women: Escape Strategies Beyond the T Visa

Asylum for Trafficked Women: Escape Strategies Beyond the T Visa

... Although the legislative history of the Act indicates concern for the victims of trafficking and recognizes that trafficking violates women's human rights, the T vis[r] ...

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Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus

Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus

... Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus Different temperature-sensitive mutants of vesicular stomatitis virus have been [r] ...

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