Viral Myocarditis
Review Article Calumenin relieves cardiac injury by inhibiting ERS-initiated apoptosis during viral myocarditis
... In order to examine whether CP influenced cell survival, terminal deoxynucleotidyltransferase- mediated dUTP Nick-End Labeling (TUNEL) assay was performed (Figure 2). TUNEL assay results revealed an increase in the ...
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Increased frequency of follicular helper T cells in mice viral myocarditis is relevant with anti ANT antoantibody
... (Th)1 [2,3], Th17 [4-7] and Th22 response [8]. What more, assisting autoantibody, produced by activated CD4 + T cells is a fundamental respect of immune re- sponses. Anti- β 1-adrenergic receptor autoantibodies, ...
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Cetirizine a histamine H1 receptor antagonist improves viral myocarditis
... decreases inflammation and fibrosis. The results sug- gest that histamine released from mast cells may play a pivotal role in the pathogenesis of viral myocarditis. However, antihistaminic agents, such as ...
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Original Article Calumenin DNA methylation and gene expression in viral myocarditis
... Abstract: The main death reason is inflammatory response of myocardial tissue caused a sharp decline in myo- cardial contractility and heart failure. At present, viral myocarditis with heart failure is lack ...
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Expression of il 23/th17 pathway in a murine model of coxsackie virus b3 induced viral myocarditis
... Viral myocarditis (VMC) has been recognized as a cause of congestive heart failure for 50 years, but its diagnosis and treatment are still ...chronic myocarditis, dilated cardiomyopathy (DCM), and ...
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Original Article Effect of emodin on the expression of TLR4 and P38MAPK in mouse cardiac tissues with viral myocarditis
... of viral myocarditis ...recorded. Viral titer was determined at day 7 by sacrific- ing 5 mice from each ...rate, viral titer, copy number of CVB3 mRNA, cardiac pathology score, and mRNA ...
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Treatment with a neutralizing anti murine interleukin 17 antibody after the onset of coxsackievirus b3 induced viral myocarditis reduces myocardium inflammation
... infectious phase and chronic immune phase of human viral myocarditis [6,7]. In past times, a multitude of studies had investigated the role of the Th1 and Th2 mediated cytokine pattern present in animals ...
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Original Article Expression of MMP-9 and hs-CRP in the serum of patients with viral myocarditis
... Abstract: Objective: This study was designed to evaluate the expression of high sensitivity C-reactive protein (hs- CRP) and matrix metalloproteinase (MMP-9) in patients with viral myocarditis (VM), and its ...
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Effect of intravenous gamma globulin on short and mid term clinical outcome in acute viral myocarditis in children
... Robinson et al. reviewed adults in Cochrane database and found only one relevant study in adults with acute viral myocarditis and did not find any beneficial effect of IVIG [31]. Similarly English et al. ...
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Increased Expressions of IL 22 and Th22 cells in the coxsackievirus B3 Induced mice acute viral myocarditis
... Acute viral myocarditis (AVMC) is characterized by myo- cardial inflammation and can progress to chronic dilated cardiomyopathy (DCM), a terminal condition requiring ...of viral myocarditis ...
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RT-PCR Detection of Coxsackievirus B3: A Viral Myocarditis
... of viral myocarditis, which accounts for more than 50% of viral myocarditis ...proteins: viral protein-1 (VP1), VP2, VP3, and ...
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Acute Viral Myocarditis, four cases in three weeks
... Acute Viral Myocarditis, four cases in three weeks Med J Malaysia Vol 44 No 4 December 1989 Acute viral myocarditis, four cases in three weeks Abd Wahab Sufarlan, MD, MRCP (UK) Lecturer, Department of[.] ...
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Valproic acid ameliorates coxsackievirus B3 induced viral myocarditis by modulating Th17/Treg imbalance
... decreased viral replication is also neces- sary for VPA-mediated amelioration of viral ...ameliorated viral myocarditis accompanied by a marked reduction in the frequency of Th17 cells and ...
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The expression and significance of protooncogene c fos in viral myocarditis
... The proto-oncogene c-fos participates in a variety of physiological process including cell growth, differentia- tion, transformation, signal transduction, and plasticity of the nervous system [1]. The expression of c-fos ...
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Distinct different expression of Th17 and Th9 cells in coxsackie virus B3 induced mice viral myocarditis
... Viral myocarditis(VMC) is an important cause of heart failure in young adults and often progresses to chronic myocarditis, dilated cardiomyopathy(DCM) requiring heart ...the viral infection ...
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Enhanced expression of superoxide dismutase messenger RNA in viral myocarditis An SH dependent reduction of its expression and myocardial injury
... in viral myocarditis is still ...of viral myocarditis, while enalapril, an ACE inhibitor without a sulfhydryl group, was not effective against acute ...of viral myocarditis and ...
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Interleukin 27 ameliorates coxsackievirus B3 induced viral myocarditis by inhibiting Th17 cells
... the myocarditis scores of heart sec- tions showed slight myocardial injury on day 4, but increased obviously in subsequent days ...the myocarditis viral replication (positive strand of CVB3) was ...
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Targeted overexpression of elafin protects mice against cardiac dysfunction and mortality following viral myocarditis
... virus–induced myocarditis than previous- ly reported in DBA/2 mice (13, ...of myocarditis allowed us to show a substantial impact of elafin transgene expression on EMC virus–induced ...
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Heart muscle performance after experimental viral myocarditis
... virus myocarditis was studied for late structural and functional ...sequelae. Myocarditis was induced in 12- and 22-day-old hamsters by inoculation with coxsackie virus ...
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The role of T helper 9(Th9) against Infectious Diseases
... Conclusion: The accurate molecular mechanisms underlying the generation and differentiation of human Th9 cells are not elucidated completely. Th9 cells exhibit Ag specific expansion in a chronic helminth infection ...
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