viral particle
Identification of critical residues of influenza neuraminidase in viral particle release
... new viral strains in the human population, including the ongoing H5N1 epizootic and swine-origin H1N1 pan- demic ...facilitating viral particle ...
14
Mutagenesis of the DI/DIII Linker in Dengue Virus Envelope Protein Impairs Viral Particle Assembly
... DV2 particle formation is not limited by steady-state expres- sion of ...of viral particles produced in the culture supernatants varied drasti- cally ...that viral particle production was not ...
12
Suppression of the Sendai Virus M Protein through a Novel Short Interfering RNA Approach Inhibits Viral Particle Production but Does Not Affect Viral RNA Synthesis
... in viral particle ...virus particle assembly and budding and confirms the observation made before with an rSeV carrying a deleted M gene ...two viral glycoproteins, was found dispens- able in ...
8
Investigation of antiviral state mediated by interferon inducible transmembrane protein 1 induced by H9N2 virus and inactivated viral particle in human endothelial cells
... In the present study, the level of IFITM1 induced by viral particle inoculation was higher than that induced by H9N2 virus infection in HUVECs (Fig. 1). The obser- vation differed to what we generally ...
12
Adsorption of bacteriophage phi 29 to Bacillus subtilis through the neck appendages of the viral particle.
... 1 Adsorption of Bacteriophage 29 to Bacillus subtilis Through the Neck Appendages of the Viral Particle NIEVES VILLANUEVA AND MARGARITA SALAS* Consejo Superior de Investigaciones Cientif[r] ...
5
The GLN Family of Murine Endogenous Retroviruses Contains an Element Competent for Infectious Viral Particle Formation
... indicated. The structures of the full-length and spliced viral transcripts are indicated (SD, splice donor site; SA, splice acceptor site). (B) Phylogeny of retroviruses, based on their RT domains. The tree was ...
7
Functional Redundancy in HIV-1 Viral Particle Assembly
... It should be noted that other groups have also examined the RNA content of the ⌬NC mutant particles. Ott et al. observed a 2-fold reduction of total RNA in the absence of NC (compared to ⱖ10-fold in our study) (27). ...
6
Nontemplated Terminal Nucleotidyltransferase Activity of Double-Stranded RNA Bacteriophage φ6 RNA-Dependent RNA Polymerase
... The viral particles partly uncoated upon entry initiate the production of positive- sense RNA segments within the cell ...the viral particle. The viral mRNA molecules extruded from the ...
11
Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action
... the viral particle and impairing its attachment to the cell ...the viral particle structure that im- pairs its attachment to the cell ...
11
Site Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome
... AAV9 viral particle: (1) a plasmid providing helper genes isolated from adenovirus that enhance viral infectivity (pHelper); (2) an ITR-containing plasmid carrying the gene of interest ...
17
Very-Low-Density Lipoprotein (VLDL)-Producing and Hepatitis C Virus-Replicating HepG2 Cells Secrete No More Lipoviroparticles than VLDL-Deficient Huh7.5 Cells
... infectious viral particle assembly and production (24, 27) via an interaction with NS5A protein ...on viral particles (28, 29) and crucial for particle infectivity via its interac- tion with ...
16
Generation and Characterization of Chicken Eggyolk Antibodies against Canine parvovirus 2 Infection
... of viral particle and antibodies by numerous methods such as ELISA, serum neutralization (SN), hemagglutination inhibition (HI), and indirect fluorescent assay (IFA) tests, virus isolation, electron ...
8
The short transcript of Leishmania RNA virus is generated by RNA cleavage.
... short viral RNA transcript corresponding to the 5 * end of positive-sense single-stranded RNAs both in virally infected cells and in in vitro polymerase ...possessed viral sequence encompassing the putative ...
7
Lack of integrase can markedly affect human immunodeficiency virus type 1 particle production in the presence of an active viral protease.
... on viral particle yield were due to the synthesis of a truncated Gag-Pol precursor or due to the disruption of a cis-acting element present in the viral RNA, the D IN and D RT-IN mutations were ...
6
Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein.
... To determine whether the amino acid changes in the MA protein domain that abolish virus replication affect viral particle assembly or release, the mutant proviruses were transfected into[r] ...
8
Foamy Virus Capsids Require the Cognate Envelope Protein for Particle Export
... Alternative membrane anchorage of the HFV Env protein. The results presented above indicated that membrane anchor- age of the HFV envelope protein via the HFV MSD domain is essential for viral particle ...
9
Infectious Entry Pathway of Adeno-Associated Virus and Adeno-Associated Virus Vectors
... observe viral Cy2 and Cy3 ...after viral infection and passage of the viral particle through the cell and into the nucleus, in agreement with earlier studies (33), and are likely solely ...
9
Dynein Engages and Disassembles Cytosol-Localized Simian Virus 40 To Promote Infection
... the viral particle, a step that is essential for productive ...hydrophobic viral particle that is integrated into the ER membrane ...drive viral disassembly ...
13
Gene therapy strategies for treating brain tumors: Retroviruses are still good candidates for therapeutic vectors
... ing malignant cells by killing these cells. Viral vectors are used to transfer the therapeutic genes into the target cells or tissues in patients. In gene therapy for congenital disorders, most of the gene ...
7
The Glycoprotein Cytoplasmic Tail of Uukuniemi Virus (Bunyaviridae) Interacts with Ribonucleoproteins and Is Critical for Genome Packaging
... proteins were analyzed by Western blotting (Fig. 6). No nu- cleoprotein or glycoprotein was detected in the immunopre- cipitates from nontransfected cells (Fig. 6, lane 1) or cells transfected with all plasmids except ...
8