Viral persistence
Viral Persistence Induces Antibody Inflation without Altering Antibody Avidity
... certain viral infec- tions, most strikingly after persistent cytomegalovirus infection, and is characterized by the accumulation and maintenance of functional effector-memory CD8 ⫹ T cells ...to viral ...
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Human papillomavirus type 16 E6 variants in France and risk of viral persistence
... Methods: One hundred and forty two women infected with HPV 16 with normal cytology, without previous treatment for cervical lesions, and with a valid second follow-up visit 4 to 16 months later, were selected from ...
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Control of Central Nervous System Viral Persistence by Neutralizing Antibody
... to persistence, as a critical number of infected cells must survive; however, this may be subverted by virus persistence in semipermissive cells or in cells refractory to immune surveillance ...cytopathic ...
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Influence of the Theiler's Virus L∗ Protein on Macrophage Infection, Viral Persistence, and Neurovirulence
... the viral life ...the persistence of the DA1 ...blocked viral persistence ...the persistence of a closely related clone, indicating that different adjustments in the expression of ...
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Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen: Replicating and Shielding Viral DNA during Viral Persistence
... or viral) through the basic patch, as well as the ability of LANA to form different oligomer arrangements and to interact with other proteins, provides the basis for the assembly of the typical LANA speckles ...
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Cell associated HIV RNA: a dynamic biomarker of viral persistence
... residual viral replication continues on ART in some patients, leading to the devel- opment of drug-resistance mutations and, as a conse- quence, therapy ...not viral RNA transcription in cells infected ...
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Viral persistence during the developmental phase of Coxsackievirus B1-induced murine polymyositis.
... In an effort to determine whether CVB1 persists and if persistence contributes to the development of chronic myositis, we have examined hindquarter skeletal muscle for the presence of vi[r] ...
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Virus-induced immunosuppression: kinetic analysis of the selection of a mutation associated with viral persistence.
... Analysis of variants isolated from the spleens of mice infected at birth with LCMV ARM showed that a Phe-to-Leu amino acid change at position 260 of the viral GP was associated with the [r] ...
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Congenital infection with atypical porcine pestivirus (APPV) is associated with disease and viral persistence
... It is known that pestiviruses may induce various clini- cal symptoms depending on virus species and strain, as well as on age and immune status of the respective hosts. Beside acute hemorrhagic disease, as documented for ...
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Viral persistence in colorectal cancer cells infected by Newcastle disease virus
... Resistance of the SW480P towards NDV-induced killing during the re-infection experiment was suggestive of a persistent NDV infection in the cells. Characteristics of persistently infected cells include reduced ...
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The role of HIV integration in viral persistence: no more whistling past the proviral graveyard
... amplification. In these studies, repeat recovery of the identical junction sequence reflects clonal expansion, as the possibility of independent integrations into the identical nucleotide position in the human genome is ...
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Molecular anatomy of viral persistence.
... CTL effectively and efficiently recognize and lyse a virally infected cell expressing regulatory proteins i.e., Nef of human immunodeficiency virus [HIV], T antigen [T-Ag] of simian viru[r] ...
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Chikungunya disease in nonhuman primates involves long term viral persistence in macrophages
... To date, little is known about the pathophysiological mecha- nisms of CHIKV infection in humans, and the only available CHIKV disease models involve infection of very young mice or mice defective in type 1 IFN signaling ...
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Equine Arteritis Virus Has Specific Tropism for Stromal Cells and CD8+ T and CD21+ B Lymphocytes but Not for Glandular Epithelium at the Primary Site of Persistent Infection in the Stallion Reproductive Tract
... a viral carrier state and a host genetic ...EAV persistence in the stallion reproductive system as a model of viral persistence in the mammalian male reproductive ...of viral ...
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Hepatitis B virus (HBV) sequence variation of cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection
... for viral persistence during chronic hepatitis B virus ...of viral persistence in chronic hepatitis and that immune selection of viral variants is not a common event in the majority of ...
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Natural History of a Recurrent Feline Coronavirus Infection and the Role of Cellular Immunity in Survival and Disease
... history, viral dynamics, and immunobiology of feline infectious peritonitis (FIP), a highly lethal coronavirus ...by viral persistence and acute lymphopenia, with waves of enhanced viral ...
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Alteration of the Leptin Network in Late Morbid Obesity Induced in Mice by Brain Infection with Canine Distemper Virus
... of viral material were expressed in the hypothalami of all CDV- infected mice and low levels of viral transcripts were detected in the hypothalami of obese mice up to 1 year after inoculation, during the ...
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Persistence of Bovine Viral Diarrhea Virus Is Determined by a Cellular Cofactor of a Viral Autoprotease
... essential viral replication factor was identified in such a virus, namely, the pestivirus bovine viral diarrhea ...of viral RNA ...with viral protein) acts as a cofactor of the NS2 ...of ...
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Acute hemorrhagic demyelination in a murine model of multiple sclerosis
... not due to increased viral load [11]. The C57BL/6 strain is considered non-demyelinating, as these mice do not develop chronic viral persistence and demyelination [12]. We now report that the fatal ...
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Role of HTLV 1 orf I encoded proteins in viral transmission and persistence
... for viral infectivity in macaques was found to be related to its role in supporting HTLV-1 infectivity of dendritic cells in vitro ...for viral persistence and spread ...
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