Viral quasispecies
Memory in Viral Quasispecies
... different viral quasispecies subjected to identical constraints (antibodies, inhibitors, new susceptible host cell types, ...of quasispecies can reemerge, contributing to the maintenance of active ...
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Ultra-deep sequencing of VHSV isolates contributes to understanding the role of viral quasispecies
... reflects viral quasispecies related adapta- tions to selective pressures set by the host availability or immune defence as discussed above will require more extensive ...
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In-Depth, Longitudinal Analysis of Viral Quasispecies from an Individual Triply Infected with Late-Stage Human Immunodeficiency Virus Type 1, Using a Multiple PCR Primer Approach
... the viral quasispecies in a woman who was triply infected with HIV-1 and who developed AIDS and passed away 15 months after ...complex viral quasispecies was found, including several ...
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Hidden Virulence Determinants in a Viral Quasispecies In Vivo
... circulating quasispecies with a higher proportion of “pathogenic” ge- ...the viral quasispecies at times shortly after posttransfection were enriched in subsets of genomes that we describe as ...
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Effect of Immune Activation on the Dynamics of Human Immunodeficiency Virus Replication and on the Distribution of Viral Quasispecies
... these cells is amplified, irrespective of the virus genotypes they contain. This leads to a change in the distribution of variants but not to any evidence of selection and raises the notion that the shifting waves of ...
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Probability of Fixation of an Advantageous Mutant in a Viral Quasispecies
... a viral quasispecies is investigated in the framework of multitype branching ...the quasispecies that will form if invasion is successful rather than on the individual fitness of the invading ...
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Analysis of pol Gene Heterogeneity, Viral Quasispecies, and Drug Resistance in Individuals Infected with Group O Strains of Human Immunodeficiency Virus Type 1
... gene quasispecies in samples obtained over a year and half from an epidemiologically linked HIV-1 group O-infected couple, the female being treated with antiretroviral agents, while the infected male remained ...
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Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications for immune recognition, viral autoimmunity and other "virus receptor" diseases
... defining viral quasispecies results from RNA pol infidelity causing rapid cumulative genomic RNA mutation a process that, if uncontrolled, would cause catastrophic loss of sequence integrity and inexorable ...
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Dynamics of Defective Hepatitis C Virus Clones in Reinfected Liver Grafts in Liver Transplant Recipients: Ultradeep Sequencing Analysis
... the viral genetic complexity after HCV reinfection of the graft liver; we also identified the characteristics of replicating HCV clones using a massively parallel ultradeep sequencing technique to determine the ...
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Population dynamics in the presence of quasispecies effects and changing environments
... evolution of viral quasispecies. Alternating acute replication of vesicular stomatitis virus (VSV), eastern equine encephalitis virus (EEEV), and Dengue virus in cells of insect and mammalian origin led to ...
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Comparison of Next Generation Sequencing and Clone Based Sequencing in Analysis of Hepatitis B Virus Reverse Transcriptase Quasispecies Heterogeneity
... of viral quasispecies and determination of antiviral-associated drug re- sistance mutations, which has been used as the reference technique to study viral ...studied viral popu- lations in ...
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Extensive Recombination among Human Immunodeficiency Virus Type 1 Quasispecies Makes an Important Contribution to Viral Diversity in Individual Patients
... HIV-1 quasispecies in the course of infection in individual ...on viral diversity, we developed a technique that permits the isolation of contemporaneous clonal viral populations resulting from ...
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A lion lentivirus related to feline immunodeficiency virus: epidemiologic and phylogenetic aspects.
... A phylogenetic analysis revealed several general trends, namely: i monophyly of viral quasispecies within individual lions, supportive of a clonal expansion of infections; ii the occurre[r] ...
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Genetic Diversity in RNA Virus Quasispecies Is Controlled by Host-Virus Interactions
... the quasispecies cloud sizes for these viruses are not constant; rather, they vary depending on the host ...the viral quasispecies is selected for a particular level of variation specific to the ...
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The Effects of Extreme Media on Political Behavior, Attitudes, and Media Selection
... of viral quasispecies sequences and estimate their frequencies from High Throughput Sequencing (HTS) data, where it incorporates different NGS reads error correction methods, aligners, and genome assemblers ...
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Seronegative Hepatitis C Virus Infection in a Child Infected via Mother to Child Transmission
... of quasispecies evolution based on the sequence of the first hypervariable region of the HCV E2 envelope protein (HVR1), which is subjected to selective pressures exerted by the host’s humoral and cellular immune ...
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Determining the Cellular Diversity of Hepatitis C Virus Quasispecies by Single-Cell Viral Sequencing
... the quasispecies pool requires persistence at the single-cell ...investigating viral diversity to ...RNA viral quasispecies diversity and evolution at the single-cell ...
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Antigenic Stimulation Specifically Reactivates the Replication of Archived Simian Immunodeficiency Virus Genomes in Chronically Infected Macaques
... ensures viral se- quence diversification. However, viral quasispecies are highly compartmentalized in vivo as a consequence of localized rep- lications at the sites of immune responses ...homogeneous ...
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Understanding how ESOL Pre Services Teachers' Prior Experiences and Background Shape their Processes of becoming L2 (Reading) Teachers
... of viral quasispecies is a subject of a great interest, particularly for chronic infections, since it can lead to resistance to existing ...characterizing viral diversity, but unfortunately standard ...
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Ribavirin-Resistant Variants of Foot-and-Mouth Disease Virus: the Effect of Restricted Quasispecies Diversity on Viral Virulence
... in viral pathogenesis (27). Specifically, the expanded quasispecies diversity of a mutagen-induced G64S eQS population ...expanded quasispecies) results in higher neurot- ropism and pathogenesis than ...
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