Viral transcription and replication
Both Viral Transcription and Replication Are Reduced when the Rabies Virus Nucleoprotein Is Not Phosphorylated
... on viral transcription and replication are caused by the net negative charge of the phosphate moiety or the structure of S or both, the phosphorylated serine at posi- tion 389 of the N was mutated to ...
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Functional Characterization of Negri Bodies (NBs) in Rabies Virus-Infected Cells: Evidence that NBs Are Sites of Viral Transcription and Replication
... support viral transcription and repli- cation leads us to consider that such structures may form around incoming ...incoming viral particles and/or inside the cytoplasm to reduce the number of ...
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Vesicular stomatitis virus in Drosophila melanogaster cells: regulation of viral transcription and replication.
... To investigate the latter possibility, kccumulation of VSV mRNAs in Droso- the infected cells were pulse-labeled with [3H]uridine at lls (0) expressed in counts per minute of various tim[r] ...
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Roles of Serine and Threonine Residues of Mumps Virus P Protein in Viral Transcription and Replication
... DISCUSSION In this study, we performed mass spectrometry, as well as a sys- tematic mutational analysis, to identify S and T residues of the P protein that are critical for MuV transcription and ...
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Transient Viral DNA Replication and Repression of Viral Transcription Are Supported by the C-Terminal Domain of the Bovine Papillomavirus Type 1 E1 Protein
... FIG. 2. Origin binding properties of truncated E1 proteins. The EE-E1 132-605 protein was tested for DNA binding activity in a DNA-protein coimmunoprecipitation assay. Lane 1 contains 1 ng (1/200) of the input 32 ...
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Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II mediated elongation of HIV 1 transcription and facilitates efficient viral replication
... reports have indicated that immunodepletion of TCERG1 from transcriptionally-active HeLa nuclear extracts de- creases Tat activation of RNAPII elongation efficiency in vitro. However, TCERG1 does not bind directly to ...
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Maribavir Inhibits Epstein-Barr Virus Transcription in Addition to Viral DNA Replication
... the replication of Epstein-Barr virus (EBV) in cell culture systems, there is still no drug that is effective and approved for use in primary EBV ...EBV replication and to have a mode of action quite ...
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Subtype associated differences in HIV 1 reverse transcription affect the viral replication
... the replication of ...reverse transcription products in virions and reverse transcription complexes (RTCs), viral DNA integration, the frequency of point mutations in the pro- virus, and the ...
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Avian and Mammalian Hepadnaviruses Have Distinct Transcription Factor Requirements for Viral Replication
... DHBV replication in nonhepa- toma cells is significantly different for these two hepadnavi- ...DHBV replication, DHBV replication was also activated by HNF3 and repressed by RXR␣-PPAR␣, whereas HBV ...
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Conservative replication and transcription of Saccharomyces cerevisiae viral double-stranded RNA in vitro.
... 17. Sequencing end-labeled DNA with base-specific chemical cleavages. Replication of double- stranded RNA of the virus-like particles in Saccharomyces cerevisiae. Semi-conservative trans[r] ...
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Human foamy virus reverse transcription that occurs late in the viral replication cycle.
... of viral cDNA is independent of superinfection and that HFV synthesizes cDNA intracellularly as a late event in the replication ...infection, viral titers were reduced by 3 or 4 orders of magnitude ...
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Roles of Phosphorylation of the Nucleocapsid Protein of Mumps Virus in Regulating Viral RNA Transcription and Replication
... Understanding the roles of phosphorylation of MuV NP will not only contribute to our knowledge of viral RNA synthesis but also aid design of novel antivirals and the next generation of vac- cines. Since MuV is not ...
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Transcription and Replication of Viral Deoxyribonucleic acid in Cells Coinfected with Adenovirus Types 2 and 12
... It was also noted that the total amount of ad 12 viral DNA in the coinfected culture was similar to the singly infected cells, which is consistent with the finding that infectious virus [r] ...
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Mapping of Betapapillomavirus Human Papillomavirus 5 Transcription and Characterization of Viral-Genome Replication Function
... HPV5 transcription in U2OS ...of viral and cellular gene ...4 Transcription start site (TSS) usage in the E1 promoter region during transient HPV5 replication in U2OS and U2OS subclone ...
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Regulation of simian virus 40 early and late gene transcription without viral DNA replication.
... Transcription of simian virus 40: SV40 DNA-RNA polymerase complex isolated from productively infected cells transcribed in vitro. Mapping the transcription site of the SV40-specific late[r] ...
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Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter
... for replication of plas- mids in HFK18 ...pXHW22 replication that contributes to different promoter activities in HFK18 ...observed transcription cannot be due to an indirect effect of Ori on plasmid ...
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Differences Of Prokaryotic Replication And Transcription
... Penn viral vectors? Phylogenomics of prokaryotic ribosomal ...the replication is contained on transcription differences of and prokaryotic replication process ...prokaryotic ...
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The transcription map of HPV11 in U2OS cells adequately reflects the initial and stable replication phases of the viral genome
... replication, whereas the E1 protein from the L- plasmid was not expressed and did not support viral DNA repli- cation as effectively as that from the L+ plasmid. This difference might be explained by mRNA ...
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Dynamics of Coronavirus Replication-Transcription Complexes
... when viral protein synthesis and formation of new RTCs was inhibited (49, 56, 70), no colocalizaton between nsp2-GFP- and nsp2-mCherry-positive structures was observed in multinucleated cells that were pos- itive ...
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Bromovirus RNA replication and transcription require compatibility between the polymerase- and helicase-like viral RNA synthesis proteins.
... The failure of heterologous la-2a combinations to direct detectable CAT expression could be due to defective synthesis of negative-strand B3CAT RNA, subgenomic CAT mRNA, or even positive[r] ...
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