Virion assembly
Two Distinct Sets of NS2A Molecules Are Responsible for Dengue Virus RNA Synthesis and Virion Assembly
... in virion assembly) could be rescued by the supply in trans of the WT NS2A from the replicon, a WT NS2A protein expressed alone, a class II mutant NS2A (G200A is lethal for viral RNA synthesis), or a ...
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The Carboxy-Terminal Fragment of Nucleolin Interacts with the Nucleocapsid Domain of Retroviral Gag Proteins and Inhibits Virion Assembly
... and virion assembly, the mutation was trans- ferred to the complete proviral ...mediate virion assembly and release directly, 293T cells were transfected with the L477P mutant or the wild-type ...
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Novel Role of vBcl2 in the Virion Assembly of Kaposi's Sarcoma-Associated Herpesvirus
... in virion assembly, we compared the amounts of the ORF45 and ORF55 tegument proteins and the ORF65 capsid protein between wild-type KSHV virions and KSHVΔvBcl2 ...of virion-associated ORF55 and ORF45 ...
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Subcellular Localization of HIV-1 gag-pol mRNAs Regulates Sites of Virion Assembly
... HIV-1 virion assembly and gRNA packaging are known (NC, Psi, dimerization, ...every virion is not yet ...initiating assembly of gRNA-devoid particles in cells expressing gRNA is also ...allow ...
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The Functional Oligomeric State of Tegument Protein GP41 Is Essential for Baculovirus Budded Virion and Occlusion-Derived Virion Assembly
... for virion assembly, and it is possible that GP41, the major tegument protein, is a highly multifunctional protein which is exposed on the outside of nucleocapsids and executes a very different envelopment ...
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Palmitoylations on Murine Coronavirus Spike Proteins Are Essential for Virion Assembly and Infectivity
... into virion envelopes at the intermediate compartment of the exocytic ...with virion membrane (M) proteins and consequent exclusion of S from ...to virion assembly than to S-induced syncytial ...
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A Functional Link between RNA Replication and Virion Assembly in the Potyvirus Plum Pox Virus
... Potyviral RNA replication has been the subject of multiple cell biology studies that have shed some light on this matter. Based on data from several laboratories working on different potyviral infections, Wei et al. (59) ...
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Using a Virion Assembly-Defective Dengue Virus as a Vaccine Approach
... a virion assembly-defective virus. We show that such an assembly-defective virus could be rescued to higher titers and infect cells for a single ...the assembly-defective virus were pro- ...
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Human Cytomegalovirus Exploits Interferon-Induced Transmembrane Proteins To Facilitate Morphogenesis of the Virion Assembly Compartment
... and virion assembly reveals a defect in both processes after IFITM ...the virion particles in the ...of virion particles and dense bodies in panels D and E are indicated with arrows of ...
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Vaccinia Virus A6 Is Essential for Virion Membrane Biogenesis and Localization of Virion Membrane Proteins to Sites of Virion Assembly
... The A6L inducible mutant also showed a novel phenotype that has not been previously reported for VACV mutants that are de- fective in virion membrane biogenesis. During normal VACV in- fection, MV membrane ...
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Hepatitis C Virus-Induced Rab32 Aggregation and Its Implications for Virion Assembly
... Rab32 is involved in the assembly step of the HCV life cycle. HCV core protein has been shown to be localized in the detergent-resistant membranes which are putative platforms for HCV particle assembly (23, ...
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Interactions between HIV-1 Gag and Viral RNA Genome Enhance Virion Assembly
... the assembly of noninfectious virus- like particles, and the viral RNA is dispensable in this ...virus assembly is currently ...virus assembly and found that packageable HIV-1 RNA enhances particle ...
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Identification of Human Cytomegalovirus Genes Important for Biogenesis of the Cytoplasmic Virion Assembly Complex
... of pUL97 is required for formation of perinuclear complexes that correspond to cVACs and for efficient production of infectious virions, but UL97 activity alone is insufficient for cVAC develop- ment (11, 18, 19). (iv) ...
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Zika Virus NS2A Mediated Virion Assembly
... and virion budding occur (23, ...flavivirus virion assembly (7–14), we decided to map its interaction with other viral proteins using an unbiased co-IP ...the virion assembly ...for ...
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The Role of the Unfolded Protein Response Regulator Bip in Hcmv Virion Assembly and Egress
... in assembly compartment maintenance, HCMV-infected fibroblasts were electroporated with CC1 fused to the mCherry fluorescent tag at 24 ...the assembly compartment and nuclei were visualized with ...intact ...
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Complete Virion Assembly with Scaffolding Proteins Altered in the Ability To Perform a Critical Conformational Switch
... cause assembly defects reminiscent of those conferred by the lethal dominant proteins in concert with wild-type ...for assembly, mutants that can productively utilize the altered external scaffolding ...
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Role of the avian retroviral protease in the activation of reverse transcriptase during virion assembly.
... The low yields of mature RT produced by trans processing of the D371 and D37K precursors led us to consider the possibilities that the mutant Gag-Pol precursors were not expressed to the[r] ...
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Kinetics of utilization of Sendai virus RNA and protein in the process of virion assembly.
... 1, the rates of utilization in assembly of viral structural proteins were linear and proportional to their representation in virus; however, the synthesis and accumulation of individual [r] ...
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Heterogeneity of vesicular stomatitis virus particles: implications for virion assembly.
... At 2 h postinfection, 52 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Vesicular stomatitis virus VSV particles formed at early times after infection contain only one[r] ...
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Functional Analysis of Potential Carboxy-Terminal Cleavage Sites of Tick-Borne Encephalitis Virus Capsid Protein
... the assembly of flavivirus virions (2, 25, ...that virion assembly also can take place when protein C and the surface proteins prM and E are translated from different translation units instead of the ...
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