Virologic Failure
Comparison of Three Different FDA Approved Plasma HIV 1 RNA Assay Platforms Confirms the Virologic Failure Endpoint of 200 Copies per Milliliter Despite Improved Assay Sensitivity
... firmed virologic failure is examined, participants are excluded from the risk set at the time of the first of the two HIV-1 RNA results above the virologic failure ...as virologic ...
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Durability of antiretroviral therapy and predictors of virologic failure among perinatally HIV infected children in Tanzania: a four year follow up
... A high level of viremia in 2008-09 did increase the odds of having one or more TAMs (p < 0.01), but did not pre- dict the ability to suppress at four year follow up (p = 0.11) (Table 3). Results of the multi-national ...
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A Prognostic Model for Estimating the Time to Virologic Failure in HIV-1 Infected Patients Undergoing a New Combination Antiretroviral Therapy Regimen
... pure virologic cri- terion and did not include stops due to other ...actual virologic failures. Other thresholds for defining virologic failure, such as a viral load > 50 copies/ml or > ...
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Antiviral Resistance and Correlates of Virologic Failure in the first Cohort of HIV Infected Children Gaining Access to Structured Antiretroviral Therapy in Lima, Peru: A Cross Sectional Analysis
... experienced virologic failure, with an additional 9% failing by the end of the second ...year. Virologic failure was significantly associated with the number of resistance mutations detected ...
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Prevalence and Factors Associated with Virologic Failure among People Living with HIV (PLHIV) Monitored in a Decentralized Health Care Facility
... Introduction: In Senegal, the decentralization of Health Care Centers has contributed significantly to the intensification of antiretroviral treatment. However, Care providers are still facing the treatment optimizing ...
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Virologic failure in HIV-positive adolescents with perfect adherence in Uganda: a cross-sectional study
... This failure might be explained as follows: first, from the Additional file 1: Table S1, regimen-specific differences were more pronounced in adolescent males, especially those enrolled on a treatment combination ...
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Impact of peer support on virologic failure in HIV infected patients on antiretroviral therapy a cluster randomized controlled trial in Vietnam
... intervention and control groups in both cumulative viro- logic failure risk and time to virologic failure after 2 years of follow-up. This result could be explained in sev- eral ways. While the ...
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Antiretroviral concentration measurements as an additional tool to manage virologic failure in resource limited settings: a case control study
... Therapeutic drug monitoring is the clinical practice of measuring specific drug levels at designated intervals with the purpose of maintaining a constant blood con- centration and optimize dosage for individual patients ...
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Immune correlates of CD4 decline in HIV infected patients experiencing virologic failure before undergoing treatment interruption
... experienced virologic failure to all three ARV drug classes, baseline CD4 count was found to be a strong predictor of short-term risk of AIDS and death ...
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Rates of switching to second line antiretroviral therapy and impact of delayed switching on immunologic, virologic, and mortality outcomes among HIV infected adults with virologic failure in Rakai, Uganda
... VF failure, CD4 at ART initiation and VL at time of VF to compute the weights and thereafter stabilized ...and virologic increase, and for a composite end- point defined as a CD4 decrease of at least 50 ...
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Immuno-haematologic and virologic responses and predictors of virologic failure in HIV-1 infected adults on first-line antiretroviral therapy in Cameroon
... of virologic failure in the younger age group of 18–29 years corroborates a previous report by Anude et ...Similarly, virologic failure was common among HIV/TB co-infected and an- aemic ...
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Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children
... monitoring. Virologic monitoring is not commonly used due to the high cost and limited ...detecting virologic failure in African HIV-infected adults ...Immunologic failure criteria have poor ...
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Virologic suppression in response to antiretroviral therapy despite extensive resistance within HIV 1 reverse transcriptase after the first virologic failure
... first virologic failure who were seen at referral centers in the city of Recife, Pernambuco, Northeastern Brazil presented a high frequency of muta- tions pertaining to secondary resistance to the use of ...
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Pre-Antiretroviral Therapy Serum Selenium Concentrations Predict WHO Stages 3, 4 or Death but not Virologic Failure Post-Antiretroviral Therapy.
... clinical failure (incident World Health Organization (WHO) stage 3, 4 or death by 96 weeks) or virologic failure by 24 ...clinical failure or virologic failure in multivariable ...
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Identifying individuals with virologic failure after initiating effective antiretroviral therapy: The surprising value of mean corpuscular hemoglobin in a cross-sectional study
... Our goal was to assess whether routinely collected clinical markers in addition to CD4 could potentially predict individuals who had an HIV RNA above 500 copies/ml after initiation of effective treatment. It is pos- ...
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Original Article HIV drug resistance and related factors in patients receiving second-line combination antiretroviral therapy in rural China
... first-line therapy: tenofovir (TDF)+3TC+ritonavir- boosted lopinavir (LPV/r) [8]. Virologic failure rates after 6 months of second-line cART of 21.8% and 17.3% have been reported in resource-limited ...
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Deep Sequencing Reveals Minor Protease Resistance Mutations in Patients Failing a Protease Inhibitor Regimen
... regimen failure. Eligibil- ity criteria were virologic failure (HIV-1 RNA load of >500 copies/ml) of a first-line nonnucleoside reverse transcriptase inhibi- tor-based regimen, with at least the ...
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Effectiveness_of_integrase_strand_transfer.8.pdf
... High virologic failure rates in patients initiating INSTI therapy with detectable viral loads was not a surprising ...with virologic failure, poor adherence to treatment has been shown to lead ...
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Profile of etravirine in the treatment of HIV in pediatrics
... As more data become available, it is hoped that etravirine will take a place in the armamentarium of antiretroviral drugs available to HIV-infected children. It is to be used in combination regimens in ...
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Dolutegravir plus lamivudine as simplification dual therapy in virologically suppressed HIV-1 infected subjects
... a pilot randomized clinical trial in which 90 HIV infected adults, virologically suppressed on stable triple ARV, without history of virologic failure and negative hepatitis B surface antigen were ...
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