Virus attachment and entry
Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection.
... cell attachment, entry and intracellular trafficking, with the L1 major protein mediating attach- ment to cell receptors, facilitating exposure of the L2 protein to furin, and enabling its subsequent ...
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Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit both Virus Attachment and Internalization during Viral Entry
... ABSTRACT Antibodies play a critical role in immunity against enterovirus 71 (EV71). However, how EV71-specific antibodies neutralize infections remains poorly understood. Here we report the working mechanism for a group ...
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Pseudotyping of Glycoprotein D-Deficient Herpes Simplex Virus Type 1 with Vesicular Stomatitis Virus Glycoprotein G Enables Mutant Virus Attachment and Entry
... prior entry of the virus into single cells, and the VD60 plaque assay therefore measured the success of this initial infection with pseudotyped gD-null virus, using intracellular gD to convert single ...
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The Macrophage Galactose-Type Lectin Can Function as an Attachment and Entry Receptor for Influenza Virus
... IAV entry pathway in addition to CME (5, ...of virus entry, likely avoiding the size restriction of clathrin- coated vesicles ...for virus attachment and entry is an important ...
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N-Glycans on the Nipah Virus Attachment Glycoprotein Modulate Fusion and Viral Entry as They Protect against Antibody Neutralization
... Nipah virus (NiV) is the deadliest known ...NiV entry into host cells and for the virus’ pathological induction of cell-cell fusion ...the attachment glycoprotein (G), upon binding to the cell ...
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Heparan Sulfate Is an Attachment Factor for Foamy Virus Entry
... 14. Feldman SA, Audet S, Beeler JA. 2000. The fusion glycoprotein of human respiratory syncytial virus facilitates virus attachment and infectivity via an interaction with cellular heparan sulfate. ...
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Attachment and entry of recombinant Norwalk virus capsids to cultured human and animal cell lines.
... the virus attachment site to interact with antibody molecules, either because of its location in a structural cleft, similar to enteroviruses and rhinoviruses (42), or possibly because the virus ...
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Bluetongue Virus Entry into Cells
... experiments. Virus stocks were generated by infection of 80 to 90% confluent BSR cells, using a multiplicity of infection (MOI) of ...min). Virus was released from the cells by three cycles of freezing and ...
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Zika virus: mapping and reprogramming the entry
... limited virus attachment/entry. First, we confirmed that the virus–receptor interaction was not affected by the basic compound; no alterations were ...
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Cellular Entry of Lymphocytic Choriomeningitis Virus
... the entry of LFV, another member of the Old World arenavi- rus ...the entry of Old World arenaviruses is likely a multi- step process, membrane cholesterol may be involved in differ- ent ...for ...
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Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein
... virus glycoprotein 2 permits assignment to class I viral fusion proteins. J. Virol. 80:5897–5907. 24. Flanagan, M. L., J. Oldenburg, T. Reignier, N. Holt, G. A. Hamilton, V. K. Martin, and P. M. Cannon. 2008. New ...
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Early events in polyoma virus infection: attachment, penetration, and nuclear entry.
... infect either permissive or nonpermissive cells, identical early events of viral infection, i.e., adsorption, penetration, and nuclear transport, were observed, suggesting that these ear[r] ...
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Human Immunodeficiency Virus and Heparan Sulfate: From Attachment to Entry Inhibition.
... the virus and consequently, neutralize the infectivity of a number of T-cell line-adapted HIV-1 ...HIV-1 attachment and entry, coupled with the recent identification of additional gp120 regions ...
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The Antiviral Effects of Curcumin Nanomicelles on the Attachment and Entry of Hepatitis C Virus
... infection and 20 % of them develop liver cirrhosis after 2 decades (29). A study was done in Mashhad in which 67% and 33% of HCV-infected patients were women and men, respectively. Generally, less than one percent of ...
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The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus
... infectious entry into Lec2-Lg cells, allowing us to define the mechanisms underlying FIG 9 Rab7 ⫹ late endosomes are not required for langerin-mediated IAV ...
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Human Cytomegalovirus Glycoprotein B Is Required for Virus Entry and Cell-to-Cell Spread but Not for Virion Attachment, Assembly, or Egress
... in virus-cell and cell-to-cell fusion has been ...for virus-cell entry, as we can infect normal fibroblasts with ⌬UL55-gB HCMV and can detect all stages of gene expression leading to the release of ...
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Ferritin light chain and squamous cell carcinoma antigen 1 are coreceptors for cellular attachment and entry of hepatitis B virus
... Discussion HBV infection targets hepatocytes in the liver. Interaction of viral proteins and host receptors was believed to be involved in HBV tropism. Characterization of HBV receptor proteins of human hepatocytes has ...
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Envelope Conformational Changes Induced by Human Immunodeficiency Virus Type 1 Attachment Inhibitors Prevent CD4 Binding and Downstream Entry Events
... immunodeficiency virus type 1 (HIV-1) CD4 attachment inhibitor with demonstrated clinical ...pseudotyped virus infection. Taken together, BMS-488043 inhibits viral entry primarily through ...
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Heparan Sulfate Proteoglycans Mediate Attachment and Entry of Human T-Cell Leukemia Virus Type 1 Virions into CD4+ T Cells
... Env-mediated entry into CD4 ⴙ T ...the entry of HTLV-1 virions into T ...to virus from MT-2, a cell line that produces high levels of ...the virus. The amount of virus internalized ...
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Integrins α2β1 and α4β1 Can Mediate SA11 Rotavirus Attachment and Entry into Cells
... over virus binding to and infection of cells transfected with ␣ 3 integrin or parent ...affect virus binding to ...SA11 virus growth observed after this time. Virus binding to K562 cells ...
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