Virus capsid
The Rubella Virus Capsid Protein Inhibits Mitochondrial Import
... Rubella virus (RV) is a human pathogen that causes severe birth defects (reviewed in reference ...between virus proteins and host cell proteins, but little is known about this ...the capsid protein, ...
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Role of the UL25 Gene Product in Packaging DNA into the Herpes Simplex Virus Capsid: Location of UL25 Product in the Capsid and Demonstration that It Binds DNA
... Since capsid assembly takes place in the nucleus, UL25 protein must be localized in the nuclei of HSV-1-infected ...other virus proteins in the late period of HSV-1 ...
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Structure of the Bluetongue Virus Capsid
... peptides in SDS-containing polyacrylamide gels One polypeptide in the case of reovirus, with a have been shown to reflect a linear relationship molecular weight of 81,000, would correspo[r] ...
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Assembly of the Herpes Simplex Virus Capsid: Preformed Triplexes Bind to the Nascent Capsid
... Capsids that incorporated the VP19C deletion mutants were examined by electron microscopy. Insect cells were multiply infected with recombinant baculoviruses expressing each of the capsid proteins (VP5, pre-VP22a, ...
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Large-Scale, pH-Dependent, Quaternary Structure Changes in an RNA Virus Capsid Are Reversible in the Absence of Subunit Autoproteolysis
... The capsid-to-procapsid transition is probably slow because there are extensive protein-protein, and possibly pro- tein-RNA, interactions in the capsid that must be broken dur- ing the expansion ...pro- ...
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The Cellular Chaperone Heat Shock Protein 90 Is Required for Foot-and-Mouth Disease Virus Capsid Precursor Processing and Assembly of Capsid Pentamers
... nism. Capsid precursors are then processed by the viral 3C or 3CD protease, facilitating their multimerization into a pentameric capsid subunit and encapsidation of the viral RNA to form virions or empty ...
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Short Self-Interacting N-Terminal Region of Rubella Virus Capsid Protein Is Essential for Cooperative Actions of Capsid and Nonstructural p150 Proteins
... ubella virus (RV) is the sole member of the genus Rubivirus in the family ...RNA virus with a genome of approximately 10 ...(SPs), capsid, E2, and E1, which are integral components of the virion ...
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Modification of a loop sequence between α helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV 1) derivative that has simian immunodeficiency virus (SIVmac239) vifand CA α helices 4 and 5 loop improves replication in cynomolgus monkey cells
... We used the CM T cell line HSC-F and CD8+ cell-depleted PBMC from CM but not from Rh for our replication exper- iments. Although we observed an improvement of viral replication in CM cells, we cannot assume that the ...
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Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation
... of capsid and PP1 ␣ was performed ...with capsid, their coimmunoprecipitation was ...VEEV capsid and PP1 ␣ ...of capsid as ...anti-VEEV capsid antibody and PP1 was detected in the ...
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Testing an Electrostatic Interaction Hypothesis of Hepatitis B Virus Capsid Stability by Using an In Vitro Capsid Disassembly/Reassembly System
... the capsid reassembly assay included a deoxynucleoside triphosphate (dNTP) mix, a random hexamer, and a control primer (15-mer) from a Novagen cDNA ...no capsid reassembly was observed, tests were repeated ...
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Expression and Self Assembly in Baculovirus of Porcine Enteric Calicivirus Capsids into Virus Like Particles and Their Use in an Enzyme Linked Immunosorbent Assay for Antibody Detection in Swine
... PEC capsid gene was subcloned into the plasmid ...PEC capsid protein was expressed in insect (Sf9) cells inoculated with the recombinant baculoviruses, and the recombinant capsid proteins self- ...
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Effects of Point Mutations in the Major Capsid Protein of Beet Western Yellows Virus on Capsid Formation, Virus Accumulation, and Aphid Transmission
... major capsid protein (P3) of cloned infectious cDNA of the polerovirus beet western yellows virus (BWYV) by manipulation of cloned infectious ...the capsid interior. The effects of the mutations on ...
10
Semliki Forest Virus-Induced Endoplasmic Reticulum Stress Accelerates Apoptotic Death of Mammalian Cells
... both virus and VRP infection. By comparing the infection of virus and VRPs lacking some or all virus structural protein-coding sequences, we demonstrate that virus envelope proteins, but not ...
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Recombinant virus vaccine for bluetongue disease in sheep.
... Bluetongue virus tubules made in insect cells by recombinant baculovirus: expression of NS1 gene of bluetongue virus serotype 10.. Structure of the bluetongue virus capsid.[r] ...
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The Capsid-Binding Nucleolar Helicase DDX56 Is Important for Infectivity of West Nile Virus
... infectious virus particles. It is also possible that virus assembly is not affected but that the virions that are secreted from DDX56-depleted cells are less ...possibilities, virus particles ...
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The Structure and Host Entry of an Invertebrate Parvovirus
... the capsid gene and from posttrans- lational modification of their N termini ...a capsid has the same amino acid sequence and is structurally the same, except that the different proteins start at different ...
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The Apical Region of the Herpes Simplex Virus Major Capsid Protein Promotes Capsid Maturation
... of capsid assembly. Of greater interest is why capsid maturation is sensitive to mutations in the polyproline loop of the VP5 apical ...the capsid shell under physiological conditions is dependent ...
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Important roles of C terminal residues in degradation of capsid protein of classical swine fever virus
... fever virus (CSFV) from Flaviviridae fam- ily is highly pathogenic to pigs and causes great economic losses in the pig industry worldwide ...17]. Capsid (C) protein encoding gene is located between viral ...
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Vesicular stomatitis virus replicon expressing the VP2 outer capsid protein of bluetongue virus serotype 8 induces complete protection of sheep against challenge infection
... Bluetongue virus (BTV) is an arthropod-borne pathogen that causes an often fatal, hemorrhagic disease in ...inactivated virus vaccines, the epidemic caused significant economic losses not only from the ...
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Africans, Cherokees, and the ABCFM Missionaries in the Nineteenth Century: An Unusual Story of Redemption
... Additional studies with TBEV replicons examined the functional role of the second transmembrane region (TM2) of the E protein independently of its role as an internal signal sequence in the polyprotein. A bicistronic ...
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