Virus entry and cell tropism
Virus Entry Is a Major Determinant of Cell Tropism of Edmonston and Wild-Type Strains of Measles Virus as Revealed by Vesicular Stomatitis Virus Pseudotypes Bearing Their Envelope Proteins
... diluted virus stock was added to each well, followed by incuba- tion at 37°C in a CO 2 ...pseudotype virus stocks were determined by counting the number of GFP- expressing cells under a fluorescence ...For ...
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Functional Murine Leukemia Virus Vectors Pseudotyped with the Visna Virus Envelope Show Expanded Visna Virus Cell Tropism
... visna virus pseudotypes. MuLV/visna virus pseudotype produc- tion was dependent on envelope construct expression and on cytoplasmic tail ...MuLV/visna virus pseudotypes were used to facilitate ...
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Ebola Virus Glycoprotein: Proteolytic Processing, Acylation, Cell Tropism, and Detection of Neutralizing Antibodies
... the cell surface molecule required for Ebola virus entry into ...(i.e., cell tropism of the pseudotyped virus is likely to be controlled only by GP), our system would also be ...
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Pathogen at the Gates: Human Cytomegalovirus Entry and Cell Tropism
... viral entry; glycoproteins; receptors; cytomegalovirus; herpesviruses; HCMV; CMV; pentamer; trimer; gH/gL ...broad cell tropism that is reflected in the multifarious tissues and organs in which the ...
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Cellular tropism and cell to cell fusion properties of the infectious bronchitis virus spike glycoprotein
... Whilst relatively little is currently known about the S glycoproteins of coronaviruses, the fusion proteins of some other viruses have been more widely studied and may offer insight into the fusion properties of ...
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Bidirectional Virus Secretion and Nonciliated Cell Tropism following Andes Virus Infection of Primary Airway Epithelial Cell Cultures
... apical virus and also provide the ba- solaterally released virus easy access to the endothelium, thereby leading to ...viral entry and receptor ...
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Lassa Virus Cell Entry Reveals New Aspects of Virus-Host Cell Interaction
... LASV entry provided novel insights into the complex interaction of this pathogen with the host ...tissue tropism of the virus does not always correlate with the extent of DG’s functional ...viral ...
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Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry.
... efficient entry of human immunodeficiency virus type 1 (HIV-1) suggests new therapeutic and preventive ...immunodeficiency virus (SIV) entry cofactors to investigate whether the macaque SIV ...
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Characterization of Lassa Virus Cell Entry and Neutralization with Lassa Virus Pseudoparticles
... in cell entry and neutralization ...conserved tropism and can be directly outcompeted by irradi- ated wt ...This cell type was previously described to be refractory to LVpp infection due to ...
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Determinants of Entry Cofactor Utilization and Tropism in a Dualtropic Human Immunodeficiency Virus Type 1 Primary Isolate
... principal entry cofactor used by HIV-1 for infection of primary macrophages (11, 33), we recently showed that macrophages also express CXCR-4 ...a virus-cell combination, rather than simply its ...
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Analysis of hemagglutinin mediated entry tropism of H5N1 avian influenza
... the cell tropism of a highly pathogenic avian influenza virus H5N1, which was originally isolated from the infected migratory birds in Qinghai Lake of Western China [16], at the entry ...
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The "V3" domain is a determinant of simian immunodeficiency virus cell tropism.
... The gpl60 env precursors of efficiently repli- cating "V3" mutants and those mutants which were severely impaired in replication because of amino acid changes close to the tip of[r] ...
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Feline Immunodeficiency Virus Cell Entry
... The PCR signal was stronger for the samples without AZT than for those incubated with AZT for both cell lines and both viral subtypes. The signal for CrFK cells increased with time, while infected U87-T4-CXCR4 ...
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Glycoprotein H of pseudorabies virus is essential for entry and cell-to-cell spread of the virus.
... mutant virus produced noninfectious progeny and was unable to spread from infected to uninfected cells by cell-cell fusion.. Thus, similar to gH of herpes simplex virus, gH of pseudorabi[r] ...
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Differential Cell Tropism of Feline Immunodeficiency Virus Molecular Clones In Vivo
... were virus isolation positive at any time point ...nonlymphoid cell population, such as tissue macro- phages, may provide a reservoir for virus in FIV-pF34-inocu- lated ...
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Egress of varicella-zoster virus from the melanoma cell: a tropism for the melanocyte.
... producing cell which originates in the neural ...host cell nucleus to the outer cell membrane, melanoma cells were infected and then processed for examination by transmission electron microscopy ...
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Infectious Cell Entry Mechanism of Influenza Virus
... For the assay of virus replication, virus was adsorbed to the cell monolayers at 10 PFU/cell at neutral pH and incubated for 4 h at 37°C in MEM-HEPES containing. 0.1 mM chloroquine at va[r] ...
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In vivo cellular tropism of human T-cell leukemia virus type 1.
... To establish the phenotype of human T-cell leukemia virus type 1 (HTLV-1)-infected cells in peripheral blood, the polymerase chain reaction was used to detect and quantitate viral DNA in[r] ...
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Demyelinating and Nondemyelinating Strains of Mouse Hepatitis Virus Differ in Their Neural Cell Tropism
... other cell types in the CNS; SMHV2-RA59 EGFP infects mainly astrocytes and neu- rons with markedly reduced ...high virus dose and produce an optimal level of viral replication that does not damage the ...
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Murine Coronavirus Requires Lipid Rafts for Virus Entry and Cell-Cell Fusion but Not for Virus Release
... inhibited virus entry and cell-cell fusion of mouse hepatitis virus (MHV), suggesting the importance of lipid rafts in MHV replication ...affect virus binding but reduced ...
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