Virus/pathogenicity
A Single Amino Acid Change in Rabies Virus Glycoprotein Increases Virus Spread and Enhances Virus Pathogenicity
... recombinant virus pathogenicity in mice. Five 10-fold serial virus dilutions were used to infect groups of 10 6- to 8-week-old female Swiss Webster mice (Taconic, ...between virus challenge ...
8
Ifit2 Is a Restriction Factor in Rabies Virus Pathogenicity
... rabies virus (RABV) and individ- ual host cell proteins is critical for the development of targeted ...in pathogenicity corre- lated to an increase in RABV mRNA and live viral load in the brain, as well as ...
9
PB1-F2 Protein Does Not Impact the Virulence of Triple-Reassortant H3N2 Swine Influenza Virus in Pigs but Alters Pathogenicity and Transmission in Turkeys
... A virus (IAV) protein, is considered to play an important role in primary influenza virus in- fection and postinfluenza secondary bacterial pneumonia in ...the pathogenicity and transmission of ...
10
Pathogenicity of the Novel A/H7N9 Influenza Virus in Mice
... human pathogenicity of H7N9 virus remain to be ...and pathogenicity of ...human virus isolates, and a number of studies have shown that this mutation is associated with increased virulence of ...
10
Two Residues in NSP9 Contribute to the Enhanced Replication and Pathogenicity of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus
... VR-2332-like PRRSVs and CH-1a-like PRRSVs), and the moderate-pathogenicity PRRSVs (NADC30/MN184-like PRRSVs) possessed both types of traits. The same situation was also observed at position 544. Therefore, we ...
16
Saffold Virus, a Novel Human Cardiovirus with Unknown Pathogenicity
... this virus may have diverse potential pathoge- nicity ...in pathogenicity. The preparation of a chimeric virus expressing green fluorescent protein may make it possible to identify the receptor for ...
5
Pathogenicity of rice yellow mottle virus and screening of rice accessions from the Central African Republic
... in pathogenicity between the RYMV isolates and, on the other hand, to different ac- cessions used in these two ...lower virus accumulation [26], thus the rice variety IRAT213 may be considered as partially ...
9
Influenza A virus acquires enhanced pathogenicity and transmissibility after serial passages in swine
... H1N1/2009 virus was derived from well-established swine influ- enza lineages; however, there is no convincing evidence that the pandemic virus was generated from a direct precursor in ...influenza ...
14
Influenza A Virus Acquires Enhanced Pathogenicity and Transmissibility after Serial Passages in Swine
... H1N1/2009 virus was derived from well-established swine influ- enza lineages; however, there is no convincing evidence that the pandemic virus was generated from a direct precursor in ...influenza ...
14
Enhanced pathogenicity and neurotropism of mouse adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations
... TABLE 1 Pathogenicity and replication of BJ27 H10N7 recombinant and mutant viruses in mice Average virus titer in sample a Lung.. Mean virus titer in sample log10 TCID50/ml ± SD.[r] ...
38
Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses
... reduced pathogenicity and corresponding longer embryo survival time induced by the PR8 FS mutant in ovo, coupled with evident modulation of virion composition in favor of HA content, suggested a strategy to ...
19
Newcastle disease virus-attenuated vaccine LaSota played a key role in the pathogenicity of contaminated exogenous virus
... disease virus (NDV)-attenuated vaccine has been widely used since the 1950s and made great progress in preventing and controlling Newcastle ...exogenous virus contamination in attenuated vaccines, while ...
11
Relaxed Selection and the Evolution of RNA Virus Mucin-Like Pathogenicity Factors
... catfish virus. This virus is a herpes- virus encoding a mucin that exhibits a repeat structure remi- niscent of those of eukaryotic ...catfish virus mucin may also be a pathogenicity ...
5
Characterization and pathogenicity of Vero cell attenuated porcine epidemic diarrhea virus CT strain
... protein of PEDV has always been used as a marker of viral variation. Under the pressure of herd immunity, the S gene of PEDV mutates frequently, with some of the missense mutations altering viral antigenicity to aid in ...
9
Attenuation of pathogenicity of fowl plague virus by recombination with other influenza A viruses nonpathogenic for fowl: nonexculsive dependence of pathogenicity on hemagglutinin and neuraminidase of the virus.
... 54-60 Copyright © 1976 American Society for Microbiology Attenuation of Pathogenicity of Fowl Plague Virus by Recombination with Other Influenza A Viruses Nonpathogenic for Fowl: Nonexcl[r] ...
7
Herpes simplex virus type 1 pathogenicity in footpad and ear skin of mice depends on Langerhans cell density, mouse genetics, and virus strain.
... 8 Herpes Simplex Virus Type 1 Pathogenicity in Footpad and Ear Skin of Mice Depends on Langerhans Cell Density, Mouse Genetics, and Virus Strain E.. BECKER* Department of Molecular Virol[r] ...
8
PAR1 contributes to influenza A virus pathogenicity in mice
... Both innate and adaptive components of the immune system are activated shortly after virus infection, which provides an efficient line of defense against IAV (7). However, excessive inflammation may also result in ...
10
Effects of infection history on dengue virus infection and pathogenicity
... A s a leading mosquito-borne infectious agent, dengue virus (DENV) infects up to 390 million people annually worldwide, 25% of whom suffer from clinical disease. Dengue epidemics have been expanding from tropical ...
9
Pathogenicity of molecularly cloned bovine leukemia virus.
... _ Southern analysis of SstI digests of PBMC DNA from infected sheep yielded detectable signal only from cloneinfected sheep L4 and 41 at 38 and 53 months p.i., respectively, and sheep 5,[r] ...
10
Comparing Phylogenetic Codivergence between Polyomaviruses and Their Hosts
... the pathogenicity of LPV are unknown at present. Simian virus 40 (SV40) was identified as a contaminant of monkey kidney cultures used to prepare the first poliovirus vaccines during the late 1950s (54, ...
7