Virus vaccines
Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines.
... 3 Incomplete Protection, but Suppression of Virus Burden, Elicited by Subunit Simian Immunodeficiency Virus Vaccines Received 9 August 1993/Accepted 9 December 1993 We compared the effic[r] ...
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Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs
... Influenza virus vaccine production is currently limited by the ability to grow circulating human strains in chicken eggs or in cell ...A virus (IAV) with an artificial genomic organization that allowed the ...
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NAction! How Can Neuraminidase Based Immunity Contribute to Better Influenza Virus Vaccines?
... ABSTRACT Neuraminidase is one of the two surface glycoproteins of influenza A and B viruses. It has enzymatic activity that cleaves terminal sialic acid from glycans, and that activity is essential at several points in ...
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Evaluation of Recombinant Influenza Virus-Simian Immunodeficiency Virus Vaccines in Macaques
... influenza virus-HIV vaccine concepts (27, 28, 44, 45, ...influenza virus vaccines to be used in combination with other vaccine vectors (27, 28, ...A virus strains and showed some boosting of ...
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Nonreplicating Influenza A Virus Vaccines Confer Broad Protection against Lethal Challenge
... nonreplicating virus vaccines would compare with replicat- ing but highly attenuated virus vaccines, we compared them with the corresponding H1N1pdm and H5N1 cold-adapted (ca) LAIV (H1 ca and ...
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Comparison of Adjuvanted-Whole Inactivated Virus and Live-Attenuated Virus Vaccines against Challenge with Contemporary, Antigenically Distinct H3N2 Influenza A Viruses
... In the face of the vast antigenic diversity of IAV, not only in swine but also in humans and avian species, efforts have been focused on exploring mechanisms to potentiate immune responses to vaccine antigens to induce ...
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Efficacy in Pigs of Inactivated and Live Attenuated Influenza Virus Vaccines against Infection and Transmission of an Emerging H3N2 Similar to the 2011-2012 H3N2v
... Methods to potentially reduce the exposure of people to swine IAV at agricultural exhibits include veterinary inspections of swine stock upon entry and/or during the exhibit, strict policies for the removal of sick pigs, ...
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Interferon, virus vaccines and antiviral drugs
... word virus is derived from the Latin word virus meaning “poison”, “slime” or ...Rabies virus cause infections of the central nervous system that can lead to paralysis or death in ...B virus ...
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Development and applications of oncolytic Maraba virus vaccines
... hPLAC1. Vaccination with MG1 caused salivation during infusion, likely attributable to nausea, followed by acute mild pyrexia that vanished within 24 hours. All cats showed transient inappetence after MG1-hPLAC1 ...
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The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease
... A virus (IAV) causes a disease burden in the swine industry in the US and is a challenge to pre- vent due to substantial genetic and antigenic diversity of IAV that circulate in pig ...inactivated virus ...
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<p>Varicella zoster virus vaccines: an update</p>
... monovalent vaccines, derived from the OKA strain (Merck and GSK), are ...MMRV vaccines have been developed (Merck and GSK) in order to facilitate their integration in current pediatric vaccination ...
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Hydrophobic Inactivation of Influenza Viruses Confers Preservation of Viral Structure with Enhanced Immunogenicity
... influenza virus vaccines, were similar between immunizations, with IgG titers from virus-infected animals being at most threefold greater than INA-inactivated X-31-immunized mice and HI titers being ...
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Individual and Bivalent Vaccines Based on Alphavirus Replicons Protect Guinea Pigs against Infection with Lassa and Ebola Viruses
... 35), vaccines for Lassa and Ebola viruses are currently not ...Lassa virus as well as bivalent experimental vaccines for both Ebola and Lassa ...
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Current progress in dengue vaccines
... the virus, immunopathological aspects are also involved in the development of dengue ...attenuated virus vaccines, live chimeric virus vaccines, inactivated virus ...
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Immune response of rhesus macaques to recombinant simian immunodeficiency virus gp130 does not protect from challenge infection.
... Because of safety concerns in the use of inactivated and live whole-virus vaccines, we evaluated the protective immunity of vaccinia virus recombinants expressing the surface glycoprotei[r] ...
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Naked DNA vaccines expressing the prM and E genes of Russian spring summer encephalitis virus and Central European encephalitis virus protect mice from homologous and heterologous challenge.
... ELISA. Direct immunoglobulin G enzyme-linked immunosorbent assay (ELISA) was performed by using methods similar to those described previously (6, 32). The viral antigen was prepared by detergent lysis of RSSE or CEE ...
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Evidence of Avian Leukosis Virus Subgroup E and Endogenous Avian Virus in Measles and Mumps Vaccines Derived from Chicken Cells: Investigation of Transmission to Vaccine Recipients
... which can detect RT activity from approximately 1 to 10 hu- man immunodeficiency virus type 1 (HIV-1) virions (22). RT activity was detected in several lots of monovalent measles and mumps vaccines, as well ...
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The immunogenicity of recombinant vaccines based on modified Vaccinia Ankara (MVA) viruses expressing African horse sickness virus VP2 antigens depends on the levels of expressed VP2 protein delivered to the host
... MVA vaccines rely on the expression of relevant immunogenic ‘ foreign ’ protein genes which are arti fi cially in- serted into their ...MVA virus vaccination has been extensively described in the ...based ...
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Attenuated Human Parainfluenza Virus Type 1 Expressing Ebola Virus Glycoprotein GP Administered Intranasally Is Immunogenic in African Green Monkeys
... per group received a booster dose, while two remained unboosted for comparison. Despite the lack of booster virus shedding, evaluation of serum samples taken 7 days following the boost revealed 5.5- and 10.4-fold ...
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Prediction of linear B-cell epitopes of hepatitis C virus for vaccine development
... On the other hand, some alternative computational methods (Table 1) have been developed for prediction of linear B-cell epitopes. These prediction methods mainly focus on peptides of a fixed length and use these peptides ...
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