Vitamin D binding protein
Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein
... Targeted disruption of the mouse DBP locus. (a) A fragment of mouse genomic DNA containing exons 4–8 of the DBP gene was used to design the targeting vector. A PGK-promoter/neomycin phosphotransferase cassette was ...
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Vitamin D binding protein is not affected by high dose vitamin D supplementation: a post hoc analysis of a randomised, placebo controlled study
... Objectives: Vitamin D binding protein (VDBP) is the main transporter of 25‑hydroxyvitamin D 3 (25‑OHD) in the ...dose vitamin D supplementation and if VDBP‑levels ...
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Identification of the C5a des Arg cochemotaxin Homology with vitamin D binding protein (group specific component globulin)
... that vitamin D-binding protein is the putative ...cochemotaxin. Vitamin D-binding protein enhanced the chemotactic activity of native C5a des Arg, but had no effect ...
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Vitamin D in individuals before onset of rheumatoid arthritis - relation to vitamin D binding protein and its associated genetic variants
... circulation vitamin D binding protein (DBP), also known as group-specific component (GC)-globulin, is the major protein transporter of vitamin D, accounting for ...
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Vitamin D binding protein sequesters monomeric actin in the circulation of the rat
... Plasma vitamin D binding protein (DBP) may scavenge actin released during cell ...actin binding proteins) would occur in vivo after cell lysis, our results suggest a role for DBP in the ...
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<p>Sputum Vitamin D Binding Protein (VDBP) GC1S/1S Genotype Predicts Airway Obstruction: A Prospective Study in Smokers with COPD</p>
... acquire vitamin D in humans. 4 Acquired vitamin D results in 25-hydroxyl vitamin D (25-OH vitamin D), 5,6 and approximately 85% of circulat- ing 25-OH ...
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<p>Attenuated serum 25-hydroxyvitamin D and vitamin D binding protein associated with cognitive impairment in patients with type 2 diabetes</p>
... Vitamin-D binding protein (VDBP), also known as group- speci fi c component acts as a major 25(OH)D ...ligand binding, 98 – 99% VDBP binding sites remain unoccupied, which ...
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Gc globulin (vitamin D binding protein) enhances the neutrophil chemotactic activity of C5a and C5a des Arg
... We investigated the possibility that the multifunctional serum protein Gc-globulin vitamin D-binding protein may also enhance the neutrophil chemotactic activity of complement-derived pe[r] ...
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Role of plasma gelsolin and the vitamin D binding protein in clearing actin from the circulation
... We determined the plasma kinetics of both actin and complexes of actin with the two high affinity actin-binding proteins of plasma, gelsolin, and vitamin D-binding protein (DBP). Actin ...
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Original Article The urea molecule 25-hydroxy vitamin D binding protein acts as a potential biomarker for liver cancer
... 25-hydroxyl vitamin D binding protein as a potential marker for liver cancer, making it one novelty of this ...25-hydroxyl vitamin D binding protein has sig- ...
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Role of group specific component (vitamin D binding protein) in clearance of actin from the circulation in the rabbit
... (vitamin D-binding protein) in the clearance of cellular actin entering the circulation was examined with 125I-labeled Gc and actin injected into a rabbit ...
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Relationship of Vitamin D Binding Protein Polymorphisms and Lung Function in Korean Chronic Obstructive Pulmonary Disease
... Purpose: Multiple genetic factors are associated with chronic obstructive pulmo- nary disease (COPD). The association of gene encoding vitamin D binding protein (VDBP, GC) with COPD has been ...
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Serum parathyroid hormone is related to genetic variation in vitamin D binding protein with respect to total, free, and bioavailable 25-hydroxyvitamin D in middle-aged Caucasians – a cross-sectional study
... of vitamin D than the total 25(OH)D ...bined) binding coefficients affected the calculated free and bioavailable concentrations by up to ...haplotype-specific binding coefficients. In ...
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Serum vitamin D binding protein is a third member of the albumin and alpha fetoprotein gene family
... and protein to existing protein and nucleic acid data banks demonstrates a strong and highly characteristic homology of the hDBP with human albumin (hALB) and human alpha-fetoprotein ...
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The GC2 haplotype of the vitamin D binding protein is a risk factor for a low plasma 25-hydroxyvitamin D concentration in a Han Chinese population
... In the blood stream, the majority of 25OHD and other VD sterols are bound to the VD binding protein (VDBP, encoded by the GC gene) [15–18], which was initially named as group-specific protein [16]. ...
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Serum vitamin D and vitamin D-binding protein levels in mother-neonate pairs during the lactation period
... similar vitamin D concentrations as their mothers were included the study, whereas those whose serum vitamin D concentration was 10 – 20 ng/ml were excluded from the study together with their ...
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Relationship of vitamin D status and bone mass according to vitamin D-binding protein genotypes
... of vitamin D metabolites circulate weakly bound to albumin, while less than 1% of circulat- ing vitamin D is in free form ...[22]. Vitamin D bound to DBP is transported within ...
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Relationship between vitamin D-binding protein polymorphisms and blood vitamin D level in Korean patients with COPD
... blood vitamin D level. Vitamin D deficiency was defined as a plasma 25-hydroxyvitamin D 3 level lower than 20 ...plasma vitamin D3 level was ...plasma vitamin D3 level was ...
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Changes in circulating 25-hydroxyvitamin D according to vitamin D binding protein genotypes after vitamin D3 or D2supplementation
... groups, respectively. All subjects were supplemented dur- ing the rainy or winter season and we did not allow taking any additional vitamin supplement. The treatment period was only 3 months and all subjects ...
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DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS naïve HIV-infected patients: a retrospective study
... 1,25-dihydroxyvitamin D; 25(OH)D: 25-hydroxyvitamin D; AIDS: Acquired immunodeficiency syndrome; aOR: Adjusted odds ratio; ART: Antiretroviral treatment; COPD: Chronic obstructive pulmonary disease; ...
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