Vitamin D Receptor (VDR)
Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes
... of vitamin D receptor (VDR) and DNA repair factors BRCA1 and 53BP1 with progerin accumulation, and that reconstituting VDR signaling via 1α,25-dihydroxyvitamin D 3 (1,25D) ...
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Association of Vitamin D Receptor (VDR) Start Codon FokI Polymorphism with Acute Myelogenous Leukemia
... The vitamin D receptor (VDR) has a thymine/cytosine (T/C) polymorphism located in the first of two potential start (ATG) codons, that can be detected by a restriction fragment length ...
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Prevalence of osteoporosis and vitamin D receptor gene polymor-phisms (FokI) in an Iranian general population based study (Kurdistan) (IMOS)
... Background: Osteoporosis, or porous bone, is a disease characterized by low bone mass density (BMD) and structural deterioration of bone tissue, leading to bone fragility and increased risk of hip, spine, and wrist ...
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Two mutations in the hormone binding domain of the vitamin D receptor cause tissue resistance to 1,25 dihydroxyvitamin D3
... We have identified and characterized two mutations in the hormone binding domain of the vitamin D receptor (VDR) in patients with hereditary vitamin D-resistant rickets. One ...
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ASSOCIATION BETWEEN VITAMIN D RECEPTOR FOKI POLYMORPHISM AND CHRONIC PERIODONTITIS IN SYRIAN POPULATION
... for vitamin D receptor (VDR) gene polymorphisms in numerous immunological ...the VDR gene were associated with the incidence of ChP in a Syrian ...Conclusion: VDR FokI ...
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Relationship between expression pattern of vitamin D receptor, 1 alpha-hydroxylase enzyme, and chemokine RANTES genes and selected serum parameters during transition period in Holstein dairy cows
... 2 D 3 exerts its pleiotropic biological actions only in target tissues that hold its intracellular protein receptor known as vitamin D receptor (VDR) which is a ligand- activated ...
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Vitamin D receptor gene polymorphisms and cardio-metabolic profile in women with hypovitaminosis D
... of vitamin D receptor (VDR) variants in determining cardiovascular risk factors has been suggested ...of vitamin D receptor (VDR) gene with metabolic profile in ...
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Gene Polymorphism of Vitamin D Receptor (VDR) in Iraqi Population
... Vitamin D receptor (VDR) gene has several ...selected VDR polymorphisms (FokI rs2228570 and TaqI rs731236) in the healthy Iraqi ...two VDR single nucleotide polymorphism were ...
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Co expression of 1α hydroxylase and vitamin D receptor in human articular chondrocytes
... the VDR protein in OA cartilage and monolayer cells ...many VDR antibodies not only bind VDR, but also possess non-specific interactions with other unidentified proteins, determined by both ...
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Age, serum 25-hydroxyvitamin D and vitamin D receptor (VDR) expression and function in peripheral blood mononuclear cells
... of VDR, 1,25D 3 -MARRS, 1α-OHase, TREM-1, cathelicidin, RIG-I, and IFN-β was measured by Real-Time quantitative Reverse Transcription Polymerase Chain Reaction (qRT- PCR) with SuperScript III Platinum SYBR Green ...
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A meta-analysis of the relationship between vitamin D receptor gene ApaI polymorphisms and polycystic ovary syndrome
... between VDR gene ApaI polymorphism and PCOS risk; 3) a case- control or cohort study based on unrelated individuals; 4) sufficient data for examining odds ratios (ORs) with 95% confidence interval (CI); and 5) ...
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VITAMIN D RECEPTOR (VDR) GENE POLYMORPHISM AND MATERNAL VITAMIN D DEFICIENCY IN INDIAN WOMEN WITH PRETERM BIRTH (PTB)
... of VDR (FokI) gene among women with preterm delivery and control women with full- term delivery is shown in Table ...of VDR FokI and TaqI was agreement with Hardy-Weinberg equilibrium in all groups in ...
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The Vitamin D Receptor (VDR) Gene Polymorphisms Fok1 In Obese Pakistanis– a Preliminary Report
... the VDR gene was associated with an increased risk of breast cancer (ff ...between vitamin D status, gene expression in immune cells and genetic variants were investigated in healthy controls (HC) it ...
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The Vitamin D Receptor (VDR) Gene Polymorphisms Fok1 In Obese Pakistanis – a Preliminary Report
... The vitamin D receptors start codon polymorphism (Fok-1) and bone mineral density in premenopausal American Black and White ...between VDR and ESR1 gene polymorphisms with bone and obesity phenotypes ...
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Functional Diversification of the Vitamin D Receptor (VDR) with Increasing Genome Complexity in Vertebrates.
... 144 Electrophoretic mobility shift assays (EMSAs) were carried out in a total volume of 20 µl containing 100 ng of recombinant VDR protein and 100 ng recombinant RXR where indicated. DNA–protein binding reactions ...
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Influence of vitamin D receptor polymorphisms on biochemical markers of mineral bone disorders in South African patients with chronic kidney disease
... associated vitamin D insufficiency to various skeletal and extra skeletal clinical end points, leading to a special interest in the determinants of vitamin D metabolites [21, ...circulating ...
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Vitamin D receptor (VDR) TaqI polymorphism, vitamin D and bone mineral density in patients with inflammatory bowel diseases
... In the next step, we carried out the analysis of bone mass parameters and serum vitamin D levels in correlation with TaqI genotypes of VDR gene. Patients with CD did not significantly differ in ...
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Computational systems pharmacology and docking explored diosgenin targets causal and effectors pathogenic signalling network of vascular calcification
... is vitamin D receptor (VDR) which is an important regulator of vascular ...affects VDR-mediated gene expression in human coronary artery smooth muscle cells and the effect is not ...
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Association between vitamin D plasma concentrations and VDR gene variants and the risk of premature birth
... min D are mediated by its receptor (VDR), which is encoded by the VDR gene (vitamin D receptor; Gene ID 7421; MIM 601769) with a chromosomal locus of ...of vitamin ...
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1,25-Dihydroxyvitamin D3 and Development of Tuberculosis in Cattle
... of vitamin D available, via UV irradiation of the skin and ...that vitamin D in the form of cod liver oil was beneficial in the treatment of tuberculosis, and calcium therapy with or without ...
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