Vitamin K-dependent protein
VKOR paralog VKORC1L1 supports vitamin K–dependent protein carboxylation in vivo
... reduces K to KH 2 is present in adult mouse liver ...and vitamin K levels from maternal transfer are low ...carboxylated protein required for signaling would be substantially less then that ...
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Plasma Protein Z Levels in Healthy and High-Risk Newborn Infants
... Neonatal RDSs are characterized by leakage of plasma proteins of varying sizes into the airspace, which leads to interstitial and intra-alveolar thrombin generation with subsequent fibrin deposition (5), systemic ...
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Resorption of implanted bone prepared from normal and warfarin treated rats
... the vitamin K-dependent protein, osteocalcin, and 93% reduced in the concentration of its characteristic amino acid, gamma-carboxyglutamic acid, was obtained from rats treated with warfarin ...
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Vitamin K dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity
... 6 protein (GAS6) and protein S (ProS) are vitamin K-dependent proteins present in plasma with important regulatory functions in systems of response and repair to ...
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miR-133a Regulates Vitamin K 2,3-Epoxide Reductase Complex Subunit 1 (VKORC1), a Key Protein in the Vitamin K Cycle
... Our results indicate, for the first time, that miR-133a exerts a novel regulatory mechanism on the expression of the main genetic factor on coumarins dose require- ments, VKORC1. After the in silico identi- fication of ...
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The health benefits of vitamin K
... Low vitamin K status (indicated by undercarboxylated MGP) is associated with increased vascular calci fi cations, and these levels can be improved by effective vitamin K supplementation 28–32 ...
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Genetic variants of the vitamin K dependent coagulation system and intraventricular hemorrhage in preterm infants
... Citrate blood samples for coagulation profile analyses were collected together with the routine laboratory testing for blood count, C-reactive protein (detection limit 0.2 mg/l) and interleukin 6 within the first ...
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Hereditary combined deficiency of the vitamin K-dependent clotting factors
... combined vitamin K-dependent clotting factors deficiency (VKCFD) is a rare congenital bleeding disorder resulting from variably decreased levels of coagulation factors II, VII, IX and X as well as ...
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WARFARIN RESISTANCE MECHANISMS AND MANAGEMENT
... of vitamin-K-dependent clotting factors type 2 (VKCFD2), and resistance to coumarin- type anticoagulant drugs (warfarin resistance, ...gene vitamin K epoxide reductase complex subunit 1 ...
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A Conserved Motif within the Vitamin K-dependent Carboxylase Gene Is Widely Distributed across Animal Phyla
... of vitamin K and the synthetic machinery to generate ␥ -carboxyglutamic ...exogenous vitamin K or a vitamin K-like cofactor and multiple enzymes for vitamin K ...
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Vitamin K dependent Calcium Binding Proteins in Aortic Valve Calcification
... atherosclerotic plaque. Calcified valves including specimens with calcific aortic stenosis, calcified porcine xenograft valves, and a calcified aortic homograft valve were analyzed for Gla content, complete amino acid ...
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Homozygous Protein C Deficiency: Observations on the Nature of the Molecular Abnormality and the Effectiveness of Warfarin Therapy
... tein C deficiency, warfarin, vitamin K-dependent fac-.. tors, hypercoagulability, disseminated intravascular coagulation.[r] ...
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A review of Warfarin woes and non Vitamin k dependent anticoagulants benefits
... in protein C (Chan et ...the vitamin K-dependent carboxylation process might explain why some patients may be at higher risk for the development of associated ...undetected vitamin ...
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IDENTIFICATION OF ADVERSE REACTIONS TO ORAL ANTICOAGULANT THERAPY IN HOSPITALIZED PATIENTS: A DESCRIPTIVE STUDY
... of vitamin K) ...of vitamin K therapy or until hospital discharge so as to assess the profile of vitamin K prescription at our ...center. Vitamin K was selected as ...
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Vitamin K and stability of oral anticoagulant therapy
... vitamine K de stabiliteit van antistollingsbehandeling kan ...vitamine K innamen of in een placebogroep. De keuze voor de dosering vitamine K werd genomen naar aanleiding van een vooronderzoek dat ...
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Guideline concordant administration of prothrombin complex concentrate and vitamin K is associated with decreased mortality in patients with severe bleeding under vitamin K antagonist treatment (EPAHK study)
... of vitamin K in association with PCC, in maintaining the normalized coagulation over six hours has been emphasized ...of vitamin K to rapidly achieve a post-reversal INR ...of vitamin ...
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THE RELATION OF VITAMIN K TO HYPERBILIRUBINEMIA
... group (III) consisted of 12 premature infants who received 30 mg of water-soluble vitamin K intramuscularly over the first 3 days of life.. The next (IV) consisted of 19 premature in- fa[r] ...
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High levels of factor IX increase the risk of venous thrombosis
... oral contraceptive use at the time of thrombosis äs well äs at the time of venipuncture, and high levels of factor VIII, XI, and the vitamin K-dependent clotling factors (all dichotomize[r] ...
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Biosynthesis of food constituents: Vitamins 1 Fat soluble vitamins a review
... retinol-binding protein. The protein-retinol complex then serves as a substrate for the conversion of retinol into retinyl ...retinol-binding protein before excretion into plas- ...
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A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain
... crystallization experiments were purchased from GenScript. FXI was con- centrated to 8 mg/mL and added to an equal volume of peptide sequence YPRHIYPDFPTDTT (P39), FNPISDFPDTTS (HKP), or RLEFPDFPIDD (LP2) to achieve a ...
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