Vivo Studies
In Vitro and In Vivo Studies of a Rapid and Selective Breath Test for Tuberculosis Based upon Mycobacterial CO Dehydrogenase
... in vivo studies used acetazolamide pretreatment at a previously validated dosage (22) to inhibit any lung carbonic an- hydrase loss of ␦47 that would decrease ...
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In Vitro and In Vivo Studies of Chemotherapeutic Doxorubicin Analogs
... Fluorescence Profiles and Calibration Curves for DOX, GPX-150 and GPX-160 DOX, GPX-150, and GPX-160 spectrofluorometric profiles were determined using a Varian Cary Eclipse fluorometer to identify the maximum excitation ...
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Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies
... The aim of the study is to prepare aqueous dispersions of lipid nanoparticles – flurbiprofen solid lipid nanoparticles (FLUSLN) and flurbiprofen nanostructured lipid carriers (FLUNLC) by hot homogenization followed by ...
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Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies
... in vivo antifungal activity of LC organogel was assessed through a quantitative analysis of the fungal infection in terms of CFUs found in the skin lesion of infected mice following the treatment ...In vivo ...
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In vitro and in vivo studies of bovine parvovirus proteins.
... When the products of a single translation reaction were immunoprecipitated first with preimmune IgG and then with rabbit immune IgG, the virion proteins were detected in approximately th[r] ...
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Devil Facial Tumour Disease: In vivo studies in mice
... In the previous chapter, immunocompetent BALB/c and C57/BL6 mice were shown to consistently reject DFTD cells (Table 3-2). This rejection was a specific immune response that produced anti-DFTD antibodies and cytokines ...
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TiO<sub>2</sub> nanotube platforms for smart drug delivery: a review
... Abstract: Titania nanotube (TNT) arrays are recognized as promising materials for localized drug delivery implants because of their excellent properties and facile preparation process. This review highlights the concept ...
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FORMULATION AND EVALUATION OF EMULGEL OF FLURBIPROFEN
... Topical drug delivery has been used for the treatment of local skin disorders. Emulgel have emerged as one of the most interesting topical delivery systems as it has dual control release system i.e. gel and emulsion ...
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INTRANASAL DRUG DELIVERY – NEW CONCEPT OF THERAPEUTIC IMPLICATIONS FOR EFFECTIVE TREATMENT OF CNS DISORDERS
... in vivo studies that higher concentration of hexarelin (a growth hormone releasing neuropeptide) was attained in the brain and cerebro spinal fluid when delivered through intranasal route when compared to ...
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The Influence of Morinda citrifolia (Noni) Fruit Juice on Collagen Deposition in the Skin: A Minireview
... The results of clinical trials involving pediatric burn patients, cigarette smokers, and overweight adults, as well as the results of a cross-sectional popu- lation study, provide more insight into the potential effect ...
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ORAL DELIVERY OF ROSUVASTATIN LIPID NANOCARRIERS: INVESTIGATION OF IN VITRO ANDIN VIVO PROFILE
... Prescreening studies enabled in deciding the suitable process parameters, while factorial design facilitated in selection of lipid to surfactant ratio for developing optimized ROS lipid ...ex vivo and in ...
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Polydopamine-Based Surface Modification of Novel Nanoparticle-Aptamer Bioconjugates for In Vivo Breast Cancer Targeting and Enhanced Therapeutic Effects
... The size and surface properties of NPs have a vital position in cellular uptake, drug release, in vivo pharmacokinetics and biodistribution [42, 43]. As presented in Table 1, the average particle size of DTX/NPs ...
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Hypoxia-targeted 131 I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery
... Figure 1: Induction of hypoxia-responsive promoter-driven transgene expression under hypoxic conditions in vitro. (A, B) For invasion assays, MSCs were stably transfected with mCherry controlled by a hypoxia-responsive ...
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In Silico Docking in Vitro Protective Effect of Certain Synthesized Flavonoids in Doxorubicin_Induced Myocardial Infarction in Rats
... Among the 5 compounds selected for in vitro angiotensin converting enzyme inhibitory assay F3 and F4 flavonoids were found to possess good activity in inhibiting the enzyme and these compounds were selected and used for ...
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Understanding Musculoskeletal Changes with Age: Stiffness in Muscle-Tendon Units and Cellular Crosstalk.
... Previous work performed by our lab sought to study mechanically simple behaviors such as hopping or bouncing to better understand elastic muscle tendon interactions at the ankle joint. 25,26 The stationary behavior of ...
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A Novel Dimeric Dipeptide Mimetic of the Nerve Growth Factor Exhibits Pharmacological Effects upon Systemic Administration and Has No Side Effects Accompanying the Neurotrophin Treatment
... Nerve growth factor (NGF) has gained much attention as a potential therapeutic agent for a number of disorders ranging from neurodegenerative diseases to inflammation, glaucoma and diabetes mellitus. Despite a success in ...
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Click here to download PDF version of the article !
... The search identified 250 publications out of which 17 duplicates were removed and 216 were excluded. Full articles were procured for 17 studies and evaluated. After evaluation, 11 of these publications were ...
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THROMBOLYTIC POTENTIAL OF PUNICA GRANATUM – A STUDY IN THE RAT MODEL
... Male Swiss Albino rats were procured from Bangalore and were housed in microloan boxes in a controlled hygienic environment at temperature 25 ± 2°C and 12 hr dark/light cycle. The study was conducted after obtaining ...
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Laser-induced corneal cross-linking upon photorefractive ablation with riboflavin
... Clinical studies were carried out after obtaining written informed consent from the patients and in full conformity with the international and Russian legislation on legal and ethical principles of biomedical ...
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In vivo pharmacokinetic studies of prodrugs of ibuprofen
... The results showed that as IBMB-M is water soluble, it did not require dissolution time. From previous kinetic studies we know that the hydrolysis rate of IBMB-M to IBA was high at acidic pH of stomach. That is ...
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