Voltage-dependent calcium channels
Voltage dependent calcium channels: Subcellular subunit localisation and targeting
... Voltage dependent calcium channels, although not generally involved in the propagation of an action potential, are critical in passing an excitatory or inhibitory signal from one cell to ...f ...
215
Peripheral nerve injury-induced plasticity of spinal voltage-dependent calcium channels: An electrophysiological study of dorsal horn neurones in the rat
... The voltage-dependent interaction exhibited by nifedipine would mean that the likelihood o f its binding to and blocking L-type VDCCs increases with increased neuronal ...
264
Pharmacological and biophysical characteristics of voltage-dependent calcium channels in rat cerebellar granule neurones
... single calcium channels in cerebellar granule ...L-type channels, one displaying sporadic short openings with a low open channel probability which are prolonged in the presence of DHP agonist, have ...
229
Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammation
... (sAHP). Reduction of the sAHP is correlated with im- proved memory acquisition [37]. This would improve neuronal sensitivity to relevant event-related stimuli, which may be overshadowed by Ca +2 “noise” during ...
14
Antispasmodic and vasodilator activities of Morinda citrifolia root extract are mediated through blockade of voltage dependent calcium channels
... of calcium from intracellular stores ...and voltage operated calcium channels and inhibition of release of calcium from intracellular ...
9
Comparative Experimental Studies of Calcium Channel Agonists and Antagonists against Ovariectomy Induced Osteoporosis In Rats
... L-types voltage dependent calcium channels (VDCC) are expressed on bone ...these channels in bone ho- meostasis is found to be ...drugs calcium channel agonist CCA (+) Bay-K-8644 ...
7
Stimulus coupling to transcription versus secretion in pheochromocytoma cells Convergent and divergent signal transduction pathways and the crucial roles for route of cytosolic calcium entry and protein kinase C
... by calcium entry through L -type voltage-gated ...When calcium entered through L -type channels, activation of secretion paralleled activation of transcription ( r 5 ...0.002). Calcium ...
14
Analysis of calcium channel properties in cultured leech retzius cells by internal perfusion, voltage clamp and single channel recording
... This ensemble of properties, including high Sr2"1" conductance and voltage-dependent activation and deactivation kinetics, set Retzius cell calcium channels apart from those found in oth[r] ...
16
Genetic aspects of primary hyperaldosteronism
... TASK channels, Kir 3.4 channels and the sodium-potassium pump ...the voltage dependent L and T-type calcium channels ...allowing calcium influx into the cell. ...
10
Scanning mutagenesis of the I-II loop of the Cav2.2 calcium channel identifies residues Arginine 376 and Valine 416 as molecular determinants of voltage dependent G protein inhibition
... WT channels displayed the hallmark characteristics of Gbg-mediated channel inhibition (Figure 1A, left), including kinetic slowing of activation and relief of inhi- bition by a strong depolarizing pre-pulse (PPF ...
7
Action Potentials in Rhodnius Oocytes: Repolarization is Sensitive to Potassium Channel Blockers
... These increases in overshoot and duration of APs in barium salines suggest that barium might not only permeate through calcium channels, but might also block a voltage-dependent potassiu[r] ...
14
Shaltiel, Lior (2013): In vivo and in vitro analysis of the retinal voltage dependent L-type Ca2+channel Ca 1.4 function. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... Intracellular calcium signals are essential for a variety of physiological processes (Berridge, 2004; Catterall, 2010; Turner et ...when calcium enters the cell via voltage gated Ca 2+ ...
132
Ion channels expression and function are strongly modified in solid tumors and vascular malformations
... cation channels, calcium Channels voltage-dependent, cation channels sperm associated, FXYD domain containing ion transport regulators, gamma-aminobutyric acid (GABA) receptors, ...
15
Symposium: “Voltage-Dependent Proton Channels Come of Age” at the Biophysical
... conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity" American Journal of Physiology: Cell ...Large-conductance ...
40
Voltage Dependent Block of Locust Muscle Glutamate Channels by Chlorisondamine
... The appearance of bursts of closings during channel openings when chlorisondamine was present in the patch pipette along with L-glutamate and when the muscle fibre was clamped at a membr[r] ...
24
Expression of voltage dependent potassium channels in first trimester human placentae
... Expression of voltage-dependent potassium channels in first trimester human placentae.. Cartwright 4, Fiona Broughton.[r] ...
12
PHARMACOLOGICAL CHARACTERIZATION OF Bunodosoma TOXINS ON MAMMALIAN VOLTAGE DEPENDENT SODIUM CHANNELS
... The three studied toxins are structurally similar. BgII and BgIII differ in the presence of Asp at position 16 instead Asn in BgIII, and this only substitution may contribute to the less potency of this toxin. Concerning ...
7
Insulin attenuates vasopressin induced calcium transients and a voltage dependent calcium response in rat vascular smooth muscle cells
... membrane potential were investigated. Insulin (1 and 100 mU/ml) shifted AVP dose- response curves to the right, reducing relative potency of AVP by 16-fold and 220-fold, respectively. Responses to AVP were significantly ...
8
Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions
... tissues where it is expressed. Taken together, the mito- chondrial localization of EFhd1, its ability to promote differentiation of 2Y-3t cells and its converse regulation by the redox factors SOD2 and HNF4a suggest that ...
14
Role of Inositol 1, 4, 5-Triphosphate on Heart Rate in Isolated Heart Models of Wistar Rats
... nucleotide-gated) channels which produces an inward current called the funny ...T-type calcium channels get activated and produce more ...The calcium ions entering the cell through this ...
144