voltage-gated calcium
Lung adenocarcinoma with Lambert–Eaton myasthenic syndrome indicated by voltage gated calcium channel: a case report
... Introduction: Lambert – Eaton myasthenic syndrome is a rare disorder and it is known as a paraneoplastic neurological syndrome. Small cell lung cancer often accompanies this syndrome. Lambert – Eaton myasthenic syndrome ...
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Deletion of a specific exon in the voltage gated calcium channel gene cacophony disrupts locomotion in Drosophila larvae
... II voltage-gated calcium channel family, member of which act to regulate many neuronal processes, including synaptic neurotransmission at the NMJ, synaptogenesis and synaptic homeostasis, as well as ...
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A molecule based genetic association approach implicates a range of voltage gated calcium channels associated with schizophrenia
... Traditional GWAS have successfully detected genetic variants associated with schizophrenia. However, only a small fraction of heritability can be explained. Gene-set/pathway based methods can overcome limitations arising ...
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Dominant-negative synthesis suppression of voltage-gated calcium channel Cav2.2 induced by truncated constructs
... Voltage-gated calcium channels subserve a number of func- tions, including neurotransmitter release, regulation of gene transcription, and muscle contraction (Catterall, ...
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Genetic Associations between Voltage-Gated Calcium Channels and Psychiatric Disorders
... Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has always been observed that ...
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Effect of Voltage-Gated Calcium Channels (Cav) Blocker on Ovariectomy Induced Osteoporosis in Rats
... of voltage gated calcium channels; mg: milligram; mm: millimeter; N: Nutone; NCBE: (National Committee of BioEthics); Nif: nifedipine; OVX: Ovariectomized; PTH: Parathyroid hormone; RANK: Receptor ...
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Responsiveness of voltage-gated calcium channels in SH-SY5Y human neuroblastoma cells on quasi-three-dimensional micropatterns formed with poly (l-lactic acid)
... to the loss of cells while preparing cross-sectional samples for SEM, our current evaluation of cell spreading was based on the projection areas under light microscopy. A concern over the current measurement may be that ...
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Voltage gated calcium channels of Paramecium cilia
... We examined the subcellular localization of expressed epitope-tagged PwA and PwB proteins by western blot analysis. A total of 100 µg of protein from the pellicle, P2, P10, or cilia suspension that was prepared from both ...
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Functional impairment of renal afferent arteriolar voltage gated calcium channels in rats with diabetes mellitus
... mal (45) or reduced (46) L-type VGCC current densities. A re- cent preliminary report indicates that coronary artery VSM cells from diabetic pigs display reduced L-type VGCC current density, which implies that fewer ...
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Calcium Channel Trafficking Blocker Gabapentin Bound to the α2δ-1 Subunit of Voltage-Gated Calcium Channel: A Computational Structural Investigation
... 14. Field, M.J.; Cox, P.J.; Stott, E.; Melrose, H.; Offord, J.; Su, T.Z.; Bramwell, S.; Corradini, L.; England, S.; Winks, J.; Kinloch, R.A.; Hendrich, J.; Dolphin, A.C.; Webb, T.; Williams, D. Identification of the ...
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Voltage gated calcium channel currents in human coronary myocytes Regulation by cyclic GMP and nitric oxide
... for voltage-gated Ca2+ entry in human coronary myocytes; (b) their inhibition by agents stimulating nitric oxide and/or intracellular cGMP production is expected ...
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Cloning and Characterization of Alternatively Spliced Voltage-Gated Calcium Channel Subunits.
... 1999). Calcium binding to the C2A and C2B domains of synaptotagmin initiates insertion of synaptotagmin into acidic phospholipids that comprise the pre-synaptic ...
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Non voltage gated calcium channels in snail heart ventricle cells
... Channel identity The following summarizes the evidence which suggests that the SG and LG channels may be Ca 2+ channels: 1 the channels conduct Na + only in the absence of Ca 2 + ; 2 the[r] ...
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Stimulus coupling to transcription versus secretion in pheochromocytoma cells Convergent and divergent signal transduction pathways and the crucial roles for route of cytosolic calcium entry and protein kinase C
... of calcium entry into the cytosol (Tables VIII and IX) in triggering transcription? Gallin and Greenberg (53) and Ginty (54) have also noted very dif- ferent neuronal gene expression responses to extracellular ...
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Genetic aspects of primary hyperaldosteronism
... the voltage-gated calcium channels and the appearance of the intracellular calcium ...intracellular calcium concentration initializes a cascade of mechanisms, leading to increased ...
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The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study
... (voltage-gated) calcium channel (LTCC) antagonists (also called calcium blockers or calcium antagonists) such as verapamil and nifedipine are licensed and widely used to treat ...
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Genetic Analysis of a Synaptic Calcium Channel in Drosophila: Intragenic Modifiers of a Temperature-Sensitive Paralytic Mutant of cacophony
... specific calcium chan- Neurotransmitter release is evoked by calcium influx nel gene products at native ...through voltage-gated calcium channels, which triggers work in Drosophila (see ...
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Current statins show calcium channel blocking activity through voltage gated channels
... the calcium curves to right in relatively in less amount ...of voltage gated calcium channels that warrants for reassessment of its dosimetry particularly in presence of other voltage ...
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Altering bioelectricity on inhibition of human breast cancer cells
... blocking voltage-gated potassium channels, stimu- lated growth of MCF7 and MDA-MB-231 ...that calcium is essential for growth of MCF7 and MDA-MB-231 since removing exter- nal calcium led to ...
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Effect of Cleistanthin C on Vascular Resistance
... the calcium oscillation. They showed that calcium oscillations became asynchronous with removal of endothelium but the amplitude of oscillations is not ...a calcium chelator and thapsigargin which is ...
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