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Vulvar Carcinoma

Vulvar carcinoma: dilemma, debates, and decisions

Vulvar carcinoma: dilemma, debates, and decisions

... Due to the rarity of the cancer and lack of randomized trials, management of this aggressive disease is shrouded with dilemmas and controversies. Although surgery has remained the cornerstone in the management of ...

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Implication of human papillomavirus 66 in vulvar carcinoma: a case report

Implication of human papillomavirus 66 in vulvar carcinoma: a case report

... HPV-66 is an a-papillomavirus considered to belong among the potentially high-risk mucosal HPV types. Nevertheless, it can also be encountered in benign lesions. Even though this HPV type is reported to be associated ...

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MiR-223-5p works as an oncomiR in vulvar carcinoma by TP63 suppression

MiR-223-5p works as an oncomiR in vulvar carcinoma by TP63 suppression

... negative vulvar carcinomas, such as in several other tumor ...in vulvar cancer carcinogenesis and ...of vulvar carcinoma (SW962) and performed in vitro ...in vulvar cancer at the biopsy ...

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Management options for vulvar carcinoma in a low resource setting

Management options for vulvar carcinoma in a low resource setting

... for vulvar carcinoma has been radical vulvectomy with superficial and deep inguinal node dissection through a single incision with at least 2-cm margins around the tumor ...of vulvar cancer is ...

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Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest

Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest

... endometrial carcinoma the occurrence of mtMSI in position 303-315 was shown to correlate with an increased mtDNA content, when normal endome- trium and tumor samples were compared ...

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Vulvar Carcinoma in a 12-Year-Old Girl With Vertically Acquired Human Immunodeficiency Virus Infection

Vulvar Carcinoma in a 12-Year-Old Girl With Vertically Acquired Human Immunodeficiency Virus Infection

... local applications of interferon-␤ for 2 months. Laser vaporization was not successful and was discontinued. Topical interferon-␤ therapy obtained some macroscopic improvement and, to date, has been repeated for a total ...

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Prognostic significance of perineural invasion in vulvar squamous cell carcinoma

<p>Prognostic significance of perineural invasion in vulvar squamous cell carcinoma</p>

... for vulvar carcinoma patients based on survival curves, it showed limited strength as an independent predictor of ...in vulvar cancer re fl ects ...

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Is the incidence of invasive vulvar cancer increasing in the United States?

Is the incidence of invasive vulvar cancer increasing in the United States?

... Increased numbers of women who are immunosuppressed may account for some of the increase in invasive vulvar cancer incidence rates. Future studies will be needed to understand the degree to which the increase in ...

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Investigation of prognostic significance of CD109 expression in women with vulvar squamous cell carcinoma

Investigation of prognostic significance of CD109 expression in women with vulvar squamous cell carcinoma

... The age of patients with squamous vulvar carcinoma included in this study ranged between 47 and 85 years. Mean age was 69.7 ± 8.0 years. When patients were evaluated according to tumor grade, 13 (50%) had ...

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Abrikossoff’s Tumor of the Vulva, Case Report and Literature Review

Abrikossoff’s Tumor of the Vulva, Case Report and Literature Review

... Abrikossoff’s tumor or granular cell tumor is a rare soft tissue neoplasm of neural origin. It usually occurs in the neck region. Up to 16% of cases occur in the vulva. This tumor is usually benign and asymptomatic. The ...

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Management of Giant Ano Vulvar Condyloma in a Structure with Limited Resources

Management of Giant Ano Vulvar Condyloma in a Structure with Limited Resources

... The tumor of Buschke-Lowenstein or giant acuminate condyloma (GAC) is a very rare tumor of the ano-vulvar region. Its incidence is estimated at 0.1% of the general population [4] [5]. It is a sexually transmitted ...

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Causation Factors in Relation to Vulvar Cancer for Indigenous Women in East Arnhem Land, Northern Territory: Qualitative Insights from the Community

Causation Factors in Relation to Vulvar Cancer for Indigenous Women in East Arnhem Land, Northern Territory: Qualitative Insights from the Community

... Issues associated with Women’s Personal and Menstrual Care: It was noted that in the ‘olden days’ women used paper bark for pads and that today they use pads, toilet paper, and tissues. one Health Professional suggested ...

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Clinical implications of immunecell infiltration in vulvar intraepithelial neoplasia

Clinical implications of immunecell infiltration in vulvar intraepithelial neoplasia

... Vulvar intraepithelial neoplasia (VIN) is a chronic vulvar skin disease with malignant potential that often causes severe and long-lasting complaints of pruritis, pain and sexual dysfunction.[1] In 2004, ...

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Vulvar melanoma: management of primary disease and repeated recurrences

Vulvar melanoma: management of primary disease and repeated recurrences

... The prognostic significance of presence of tumor regression is controversial in cutaneous melanoma, but a large study of vulvar melanomas showed regression in 25% of cases. This finding was associated with ...

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Beware of human papillomavirus. a miscreant behind more than just breast cancers (a caution bell to young women)

Beware of human papillomavirus. a miscreant behind more than just breast cancers (a caution bell to young women)

... This is a historical event in Medicine and the prophylactic HPV vaccine have been powerful tools of primary prevention of cervical cancer and other HPV associated diseases. Vaccination has been shown to reduce the ...

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Vulvodynia: a consideration of clinical and methodological research challenges and recommended solutions

Vulvodynia: a consideration of clinical and methodological research challenges and recommended solutions

... chronic vulvar pain, is a prevalent genital pain condition that results in significant impairment to sexual, relational, and psychological functioning of affected women and their romantic ...

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Vulvar Lichen Sclerosus: Current Perspectives

<p>Vulvar Lichen Sclerosus: Current Perspectives</p>

... Although the etiology of LS is still unclear, evidence suggests that LS is an autoimmune disorder with a genetic component. Familial studies indicate a positive family history of LS, with 12% of over 1000 women with ...

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Genitofemoral neuralgia: adding to the burden of chronic vulvar pain

Genitofemoral neuralgia: adding to the burden of chronic vulvar pain

... nociceptive vulvar pain typically elicit visible epithelial alterations (eg, lichen planus, vulvar intraepithelial neoplasia, and genitourinary syndrome of menopause) prompting clinical diagnosis, though ...

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Vulvar cancer: epidemiology, clinical presentation, and management options

Vulvar cancer: epidemiology, clinical presentation, and management options

... Vulvar cancer can be distinguished into two separate dis- eases: the first type involves a human papillomavirus (HPV) infection that causes vulvar intraepithelial neoplasia (VIN), a predisposing factor for ...

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Vaginal rejuvenation: current perspectives

Vaginal rejuvenation: current perspectives

... Female genital cosmetic surgery (FGCS) includes several surgical interventions (such as vaginal rejuvenation, labiaplasty, vulvar liposculpturing, re-virgination with hymenopla[r] ...

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