VX2 tumor
A small interfering RNA targeting vascular endothelial growth factor efficiently inhibits growth of VX2 cells and VX2 tumor model of hepatocellular carcinoma in rabbit by transarterial embolization-mediated siRNA delivery
... rabbit VX2 carcinoma cells was reduced by ...rabbit VX2 liver-transplanted model, the growth ratios of tumors at 28 days after TAE-mediated siRNA delivery were ...of VX2 tumor into the liver ...
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Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models
... The tumors in the livers (Fig. 3A, a-c) and muscles (Fig. 3A, a’-c’) were clearly shown on contrast-enhanced T1-weighed MR images and demonstrated similar changes on imaging among the different groups. At baseline, the ...
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Original Article Experimental study of image-guided percutaneous microwave ablation in rabbit lung VX2 tumor model
... Lung cancer is one of the most common malig- nancies worldwide, and the current therapies include surgery, radiation therapy and chemo- therapy [1-3]. Surgical intervention is usually performed in patients with cancers ...
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Combination therapy involving radiofrequency ablation and targeted chemotherapy with bevacizumab plus paclitaxel and cisplatin in a rabbit VX2 lung tumor model
... the VX2 tumor may exhibit different treatment responses and is consid- ered more malignant than human lung ...for VX2 lung model [15], but it may be clinically relevant to give anticancer drugs prior ...
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The evaluation of anti-angiogenic effects of Endostar on rabbit VX2 portal vein tumor thrombus using perfusion MSCT
... The standard human dose for Endostar is 15 mg/m 2 /day. After conversion from human (60 kg) to rabbit, the dose used in this study was 45 mg/m 2 /day, calculated based on the Meeh-Rubner formula: A = k × (W 2 / 3 ) / ...
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A Correlative Study between CT Perfusion Parameters and Angiogenesis in Rabbit VX2 Liver Tumors
... after VX2 tumor cells survive im- plantation, they may exhibit inconsistent increases in tumor angiogenesis and blood perfusion at different times; however, in this experiment, blood perfusion and ...
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Percutaneous microwave coagulation for eradication of VX2 tumors subcutaneously in rabbits
... The VX2 cell line, used for tumor implantation, was obtained from the Surgery Department of our ...the VX2 tumor in- oculation and other procedures. The required tumor tis- sue, taken ...
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Transarterial oily chemoembolization with lidamycin shows potent therapeutic efficacy in VX2 rabbit liver tumor
... University. VX2 carcinoma cells were pur- chased from the animal center of Sun Yat-sen University and then maintained as a tumor line in our ...of VX2 tumor cells, a cryopreserved VX2 ...
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Rabbit VX2 lung tumor models can form early nodal metastases
... implanted a 1-mm 3 piece of minced VX2 tumor directly into the lung under CT guidance with no reported cell count [12–14]. Those studies that most clearly identified the time of nodal metastasis relied on ...
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Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells
... rabbit VX2 tumor cells could allow for CSC ...rabbit VX2 tumor model to study human hepatocellular carcinoma and provide concrete evidence that ALDH1 is expressed by and can be a functional ...
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Original Article Effect of ischemia reperfusion on rabbit VX2 cells in a hepatocellular carcinoma model
... the tumor homogenate into rabbit thigh muscles. After the tumor grew gradually to a size of 4-5 cm in diameter, it was removed from the hind leg of an animal for preparation of the cell suspen- ...sion. ...
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Intraoperative Cryosurgical Freezing Assists with Local Drug Delivery and Targeting of Tumor Fluids in VX2 Model, which Translates in Locoregional Drug Targeting of Tumor Fluids during Cryoprobe-Assisted Surgical Resection of Breast Cancer
... in VX2 compared to BRCA, the frozen margin regardless of its size is the drug driver; drug transport within unfrozen interstitial fluid pathways follows the pressure gradient created between needle tip and ...
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Thermo-sensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors
... A VX2 liver tumor rabbit model was established as previously described ...All VX2 rabbits were fed for 18-24 days after a VX2 tumor was implanted and examined with computed tomography ...
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Induction of VX2 para-renal carcinoma in rabbits: generation of animal model for loco-regional treatments of solid tumors
... VX2 tumor fragments (obtained by ...containing tumor fragments were placed in a 37 °C water bath for a rapid but not complete ...thawing. Tumor pieces were removed carefully from the cryo- ...
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Original Article Hepatic arterial administration of sorafenib and iodized oil effectively attenuates tumor growth and intrahepatic metastasis in rabbit VX2 hepatocellular carcinoma model
... planted VX2 tumors compared to pharmorubi- cin and cis-DDP, which may be a anti-tumor mechanism of TACE-is ...the tumor area. Downregulation of VEGF could suppress tumor growth ...in ...
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Mesenchymal Stem Cells Promote Tumor Progression via Inducing Stroma Remodeling on Rabbit VX2 Bladder Tumor Model
... The tumor volume was measured by ultrasound at the time points of 1st, 2nd, 3rd and 4th week after ...the tumor tissue expressions of basic fibroblast growth factor (bFGF), transforming growth factor beta 1 ...
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Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using αvβ3-Targeted Theranostic Nanoparticles
... of Vx2 tumor neovasculature around 12 days post implantation or longer, MR sensitivity may permit only assessment of the macroscopic changes of neovasculature and may not adequately resolve mi- croscopic ...
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Tumor-associated macrophages: an accomplice in solid tumor progression
... killing tumor cell by producing reactive oxygen/nitrogen species (ROS/RNS) and pro-inflammatory cytokines such as IL-1β, IL-6, tumor necrosis factor α ...promote tumor development. Therefore, they ...
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Tumor-associated collagen signatures: pushing tumor boundaries
... breast tumor emerged and, since 2011, is gaining recognition and research ...“ Tumor-associated collagen signatures ” describe 3 distinct layers of collagen which radiate outward in shells from the main ...
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Original Article Inflammation and cancer: inhibiting the progression of residual hepatic VX2 carcinoma by anti-inflammatory drug after incomplete radiofrequency ablation
... endogenous tumor promoter, contributing to the tissue remodeling and stro- mal development necessary for tumor growth and spread ...during tumor initiation resulted in an increase in tumor ...
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